An interventional study of low vs high glycemic index diet in Obesity, sponsored by Boston Children's Hospital. Completed at 1 site in United States. Open to male participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2010-08-30.
Sponsored by Boston Children's Hospital · Not applicable, Interventional, and Prevention
This study will compare the physiological effects of two isoenergetic, nutrient-controlled diets that differ in glycemic index. The diets will be studied in obese adults in a 10-day crossover feeding trial.
This study will compare the physiological effects of two isoenergetic, nutrient-controlled diets that differ in glycemic index. The diets will be studied in obese male adults in a 10-day crossover feeding trial. Hypothesis: Obese subjects will show improvements in clinical endpoints associated with risk for diabetes and cardiovascular disease (CVD) after consuming a controlled low (compared to high) glycemic index diet for 10 days. 1º endpoint: insulin sensitivity as measured by the modified Frequently Sampled Intravenous Glucose Tolerance Test (FSIVGTT). 2º endpoints: CVD risk factors; postprandial studies of oxidative stress; thermic effect of food.
6,296 studies on the registry are indexed under Obesity; 1,692 are open to participants now.
This study's enrollment of 24 is below the median of 78 across 4,878 interventional studies indexed under Obesity.
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Of its 31 completed or terminated interventional studies of FDA-regulated products, 18 (58%) have results posted.
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Exclusion Criteria:
Insulin sensitivity as measured by FS-IVGTT
CVD risk factors
Postprandial studies of oxidative stress
Thermic effect of food
This study is completed, as verified in Aug 2010. You cannot join it, but the record below documents what was studied.
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Boston Children's Hospital