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CompletedNCT00011674Updated Mar 23, 2006

Early Exposure to Lead and Adolescent Development

An observational study in Lead Poisoning, sponsored by National Institute of Environmental Health Sciences (NIEHS). Completed at 1 site in United States. Open to participants aged 0 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2006-03-23.

Sponsored by National Institute of Environmental Health Sciences (NIEHS) · Observational

Study type
Observational
Model
Defined population
Time perspective
Prospective
Enrollment
300
Ages
0 Years and older
Sex
All
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Study summary

This prospective cohort study examines the role of prenatal and early postnatal lead exposure on the neuropsychological status and social adjustment of adolescents enrolled in the Cincinnati Lead Study. We are examining the relationship between moderate exposure to lead and neuropsychological deficits, difficulties in peer relationships, personality disturbances and juvenile delinquency. This birth cohort of approximately 300 subjects has been followed since 1980 with regularly scheduled assessments of blood lead concentrations, health history, social and hereditary factors, and neurobehavioral development.

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Conditions studied

  • Lead Poisoning

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Keywords

  • Lead
  • Prenatal
  • Development
  • Children
  • Psychology
  • Toxicology
  • Teratology
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In context

Lead Poisoning

27 studies on the registry are indexed under Lead Poisoning; 2 are open to participants now.

This study's enrollment of 300 is below the median of 350 across 14 observational studies indexed under Lead Poisoning.

Browse Lead Poisoning studies →

Lead sponsor

National Institute of Environmental Health Sciences (NIEHS) is the lead sponsor of 183 studies on the registry; 18 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
0 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Eligibility criteria

Subjects for the Cincinnati Lead Study were recruited prenatally if their mothers resided in areas within Cincinnati, Ohio where there has historically been a high incidence of lead poisoning. Infants were eligible for follow-up if they were greater than 1500 grams at birth and had no disqualifying medical conditions such as defined genetic syndromes or other serious complications that may adversely affect neurobehavioral development.

05

Study design

Observational model
Defined population
Time perspective
Prospective
Enrollment
300 participants
06

Study locations

1 site
  • Findlay Street Clinic
    Cincinnati, Ohio 45214, United States
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 23, 2006, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00011674
First posted
Feb 28, 2001
Start date
May 1997
Completion
May 2001
Last update
Mar 23, 2006
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2006. You cannot join it, but the record below documents what was studied.

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