Yale University: Tobacco Use Disorder trials

The registry lists 57 Tobacco Use Disorder studies with Yale University as lead sponsor. 5 are open to participants now and 32 have results posted.

Early Phase 1 7Phase 1 17Phase 2 13Phase 3 1Phase 4 2No phase 22(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Smoking Cessation Medication And Rewards Using a Teamlet to Treat Tobacco Use Disorder (SMARTTT 2.0) Among Persons With HIV: A Multi-site Hybrid Type 2 Effectiveness-implementation TrialNot yet recruitingNCT07835555Phase 4
• Sex Differences in E-Cigarette PerceptionRecruitingNCT07398976Not applicable
• A Trial of Varenicline for E-cigarette CessationRecruitingNCT07040566Phase 2
• Effects of E-cigs vs Pouches on Cigarette Smoking and AddictionRecruitingNCT06077240Not applicable
• Effects of Novel E-cigarette Constituents on Adults TCORS 3.0RecruitingNCT05932745Not applicable
• Sex Differences in E-cig Perception: Study 1CompletedNCT05432830Not applicableResults posted
• Nicotine's Potential Abuse With MentholCompletedNCT04535362Early Phase 1Results posted
• Effects of Menthol in E-cigarettes on Smoking BehaviorsCompletedNCT04521647Phase 1Results posted
• The Interaction of Flavor With Nicotine Form in Adult SmokersCompletedNCT04262817Phase 1Results posted
• Switching to Potential Reduced Exposure Products in Adult SmokersCompletedNCT04250727Not applicableResults posted
• Effects of E-Cigarette Flavors on Adults TCORS 2.0CompletedNCT03635333Phase 1Results posted
• Effects of E-cigarette Flavors on Youth TCORS 2.0CompletedNCT03634839Phase 1Results posted
• Nicotine Delivery Rate and Its Abuse Potential: Impact of MentholCompletedNCT03580525Early Phase 1Results posted
• Effects of Flavors on Nicotine Reinforcement in SmokersCompletedNCT03243630Early Phase 1Results posted
• Optimizing Tobacco Dependence Treatment in the Emergency DepartmentCompletedNCT02896400Phase 3Results posted
• Treatment for Nicotine Addiction in WomenCompletedNCT02448654Not applicableResults posted
• Imaging Extrastriatal Dopamine Release in Tobacco Smokers and NonsmokersCompletedNCT02348385Results posted
• New Approaches to Smoking Cessation in Heavy DrinkersCompletedNCT02151591Phase 1Results posted
• The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco UsersCompletedNCT02102100Not applicableResults posted
• Progesterone for Smoking Relapse Prevention Following DeliveryCompletedNCT01972464Phase 2Results posted
• A Study to Help People Quit Smoking.CompletedNCT01880099Not applicableResults posted
• Test-retest Reproducibility of [11C]PHNO PET Using the Constant Infusion ParadigmCompletedNCT01699607Not applicableResults posted
• Implementation of HIT-Enhanced Tobacco Treatment for Hospitalized SmokersCompletedNCT01691105Not applicableResults posted
• Screening to Augment Referral to Treatment- Project STARTCompletedNCT01539525Not applicableResults posted
• Nicotine Reinforcement and Aversion in Young Adult Light SmokersCompletedNCT01495819Early Phase 1Results posted
• A Smoking Cessation Treatment for Adult WomenCompletedNCT01422239Phase 1Results posted
• Treating Low-Income Smokers in the Hospital Emergency DepartmentCompletedNCT01328431Not applicableResults posted
• Smoking Cessation for Smokers With Sleep ProblemsCompletedNCT01277887Not applicableResults posted
• Enhancing a High School Based Smoking Cessation ProgramCompletedNCT01145001Not applicableResults posted
• Nicotine Vaccination and Nicotinic Receptor OccupancyCompletedNCT00996034Phase 2Results posted
• Varenicline for Smoking Cessation in Heavy Drinking SmokersCompletedNCT00860028Phase 2Results posted
• Message Framing for Telephone Quitline CallersCompletedNCT00589277Phase 1/2Results posted
• Efficacy of Varenicline in Methadone-Stabilized Cocaine UsersCompletedNCT00567320Not applicableResults posted
• Study of Lunesta Versus Placebo for Sleep Problems Related to Smoking Cessation and ZybanTerminatedNCT00511134Phase 4Results posted
• Naltrexone and Varenicline: Weight Gain and Tolerability in Cigarette SmokersCompletedNCT00502216Phase 1/2Results posted
• Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight GainCompletedNCT00129246Phase 1/2Results posted
• Targeted Interventions for Weight-Concerned SmokersCompletedNCT00105482Phase 2Results posted
• Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic PsychedelicsTerminatedNCT06624137
• Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2Active, not recruitingNCT06006143Phase 2
• IV Pulsed-Nicotine as a Model of Smoking: The Effects of Dose and Delivery RateCompletedNCT05176418Early Phase 1
• Nicotine Differences in SmokersCompletedNCT05159934Phase 1
• Acute Effects of Vaping Nicotine on Cognition in Young AdultsCompletedNCT04901208Not applicable
• Glucocorticoid Antagonist Treatment for Tobacco Use DisorderTerminatedNCT03248713Early Phase 1
• Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 2CompletedNCT03168191Phase 1
• Short Term Effects of Electronic Cigarettes in Tobacco Dependent AdultsCompletedNCT02498145Not applicable
• Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1CompletedNCT02179034Phase 1
• Effects of Brief Training on Craving RegulationCompletedNCT02153749Not applicable
• Atomoxetine's Effects On Nicotine Response And Stress Response In SmokersWithdrawnNCT02046551Phase 1/2
• Tobacco Approach Avoidance Training for Adolescent Smokers-1CompletedNCT01625767Phase 2
• Tobacco Approach Avoidance Training for Adolescent Smokers-2CompletedNCT01625637Phase 2
• Varenicline on Reward Responses and Cognition in Adolescent SmokersCompletedNCT01624428Phase 1
• Mindfulness Training for Smoking CessationCompletedNCT01144689Not applicable
• Alcohol Counseling for Telephone Quitline CallersCompletedNCT01120080Phase 1/2
• Sensitivity to Intravenous Nicotine: Genetic ModeratorsCompletedNCT00969137Phase 1
• GABA (Gamma Amino Butyric Acid) Medication for TobaccoCompletedNCT00644137Early Phase 1
• Effect of Progesterone on Smoking Behavior in Male and Female SmokersCompletedNCT00271206Phase 1
• Framing Messages for Smoking Cessation With Bupropion - 6CompletedNCT00104598Not applicable