Yale University: Diabetes Mellitus, Type 1 trials

The registry lists 49 Diabetes Mellitus, Type 1 studies with Yale University as lead sponsor. 6 are open to participants now and 12 have results posted.

Early Phase 1 8Phase 1 3Phase 2 2Phase 3 1No phase 35(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Home-based Oral Glucose Tolerance Test for Type 1 Diabetes ScreeningRecruitingNCT07155252
• Digital Mindfulness for Young Adults With Type 1 DiabetesRecruitingNCT07062887Not applicable
• T1CARE: A Trial of a Novel Intervention to Address Social Determinants of Health in Young Adults With Type 1 DiabetesRecruitingNCT07059806Not applicable
• Building and Sustaining Exercise Habits for Adults With Type 1 DiabetesRecruitingNCT06967701Not applicable
• Glu-COACH: a Peer-mentoring Intervention to Reduce Disparities in Continuous Glucose Monitor (CGM) UseRecruitingNCT06171412Not applicable
• Regulation of Brain Glucose Metabolism in Type 1 DiabetesRecruitingNCT05317455Early Phase 1
• Digital Exercise for Middle-Aged Adults With Type 1 Diabetes and Other Absolute Insulin Deficiency DiabetesCompletedNCT06098729Not applicableResults posted
• Yale-Harvard Hotel-based Closed-Loop Studies in Children (HY-GRAID)CompletedNCT04255381Not applicableResults posted
• Very Low Carbohydrate Diet as an Adjunctive Therapy for Youth Type 1 DiabetesCompletedNCT04082884Not applicableResults posted
• Mechanisms for Restoration of Hypoglycemia AwarenessCompletedNCT03738852Early Phase 1Results posted
• Effect of Adiposity on Hepatic and Peripheral Insulin Resistance in Type 1 DiabetesTerminatedNCT03582956Not applicableResults posted
• The Effect of Bolus Speed of Rapid-Acting Insulin Analog Absorption and Action in Individuals With Type 1 DiabetesCompletedNCT03542682Not applicableResults posted
• Using an Artificial Pancreas System in Older Adult Type 1 Diabetes Mellitus PatientsTerminatedNCT03353792Not applicableResults posted
• Effect of Canagliflozin in T1DM (Type 1 Diabetes Melitus) After Interruption of Continuous Subcutaneous Insulin InfusionCompletedNCT02673138Not applicableResults posted
• A Phase II Trial to Examine the Effect of Subcutaneous Exenatide (Bydureon®) on Glucose Control in Patients With Type I DiabetesCompletedNCT01928329Phase 2Results posted
• Effect of Formoterol on the Counterregulatory Hormonal Response to Hypoglycemia in Type 1 Diabetes.CompletedNCT01194479Not applicableResults posted
• Effect of Medium Chain Fatty Acids on Cognitive Function During Acute Hypoglycemia in Patients With Type 1 DiabetesCompletedNCT00592072Not applicableResults posted
• Anti-CD3 mAb Treatment of Recent Onset Type 1 DiabetesCompletedNCT00378508Phase 2Results posted
• Avatar-based Social Physical ActivitySuspendedNCT05662826Not applicable
• Virtual Physical Activity for Type 1 DiabetesCompletedNCT05163912Not applicable
• Real World Evaluation of Advisor Pro in Clinical PracticeWithdrawnNCT04904718Not applicable
• Guided User-initiated Insulin Dose Enhancements (GUIDE) to Improve Outcomes for Youth With Type 1 DiabetesWithdrawnNCT04259775Not applicable
• Mobile Physical Activity for Type 1 DiabetesCompletedNCT04204733Not applicable
• Pathogenesis of the Cardiometabolic Risk in Youth With Type 1 DiabetesTerminatedNCT04101045Not applicable
• Diluted Insulin in Young Children: Bigger Volumes for Smaller PatientsCompletedNCT03666065Early Phase 1
• Hybrid Closed-Loop Insulin Delivery System in Type 1 Diabetes Candidates for a Living Donor Kidney TransplantWithdrawnNCT03494010
• Reducing the Risk of Metabolic Decompensation in Diabetic Adolescents by Supervised School Administration of InsulinCompletedNCT03400501Early Phase 1
• A Pilot Study of Biomarkers of Stress in Youth Who Use Teens.ConnectCompletedNCT02970656Not applicable
• Sleep, Coping and Executive Functioning in Youth With Type 1 DiabetesCompletedNCT02908555
• A Reinforcement Approach to Increase Use of CGMCompletedNCT02907346Not applicable
• Bright 1 Bodies Weight Management ProgramCompletedNCT02768987Not applicable
• Blood Glucose Variability and Insulin Action During Menstrual Cycle in Females With Type 1 DiabetesCompletedNCT02693938Not applicable
• Physical Activity and Glycemic Control in AdolescentsCompletedNCT02674828Not applicable
• Brain Ketone Metabolism in Type 1 DiabetesCompletedNCT02471040Phase 1
• A Reinforcement Approach to Improve Diabetes ManagementCompletedNCT02167243Not applicable
• Preventing Hypoglycemia During Exercise With Proactive Snacking on Closed LoopCompletedNCT02135068Early Phase 1
• AbATE Follow-Up StudyCompletedNCT02067923
• Warming up to Sensors: Does Site Warming Improve Continuous Glucose Monitor Performance?TerminatedNCT01954459Early Phase 1
• Acceleration of Insulin Action by Hyaluronidase During Closed-Loop TherapyCompletedNCT01945099Early Phase 1
• Study of the Acute Metabolic Effect of Exenatide in Type 1 DiabetesCompletedNCT01855490Phase 1
• Effect of the InsuPatch on Automated Closed-loop Glucose Control in Type 1 DiabetesCompletedNCT01787318Early Phase 1
• Teens-Connect: Preventive Psycho-education for Transitioning Teens With DiabetesCompletedNCT01783327Not applicable
• Effect of a Medium Chain Triglyceride Supplemented Diet on Cognitive Function and Brain Activation in Type 1 Diabetes.CompletedNCT01315171Not applicable
• Positron Emission Tomography (PET) Imaging of Pancreatic Beta-Cell Mass in Healthy and Type 1 Diabetic PatientsCompletedNCT00958997
• TEENCOPE: An Internet Coping Skills Training Program for Teens With Type 1 DiabetesCompletedNCT00684658Phase 3
• Evaluation of Pharmacokinetics and Pharmacodynamic Properties of Rapid-Acting Insulin AnalogsCompletedNCT00652288Phase 1
• The Impact of Pancreatic Islet Cell Allotransplantation on Cognitive Function in Type 1 Diabetes MellitusCompletedNCT00590876
• Investigation Into the Effects Upon Brain Response to Change in Circulating Glucose Levels in Diabetes MellitusCompletedNCT00580710
• Impact of Hypoglycemia Unawareness on Brain Metabolism Cognition in T1DMCompletedNCT00575783