Wake Forest University Health Sciences: Leukemia trials

The registry lists 36 Leukemia studies with Wake Forest University Health Sciences as lead sponsor. 3 are open to participants now and 9 have results posted.

Phase 1 9Phase 2 12Phase 3 1No phase 16(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study of LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive Acute Lymphoblastic Leukemia (ALL)Not yet recruitingNCT07614022Phase 1
• Pre-malignant States to Hematologic Malignancies in FirefightersRecruitingNCT06870760
• Factors Affecting Post-transplant Cyclophosphamide (PTCy) EfficacyRecruitingNCT03555851
• Leukemia Stem Cell Detection in Acute Myeloid LeukemiaTerminatedNCT02927938Phase 3Results posted
• CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Granulocytic SarcomaCompletedNCT02484391Phase 1Results posted
• Vincristine Sulfate Liposome in Treating Patients With Relapsed or Refractory Acute Myeloid LeukemiaTerminatedNCT02337478Phase 2Results posted
• Bioelectrical Impedance Measurement for Predicting Treatment Outcome in Patients With Newly Diagnosed Acute LeukemiaCompletedNCT01869777Not applicableResults posted
• A Phase II Open-Label Study of High-Dose Cytarabine and Clofarabine in Adult Patients With Refractory or Relapsed Acute Myelogenous Leukemia or Refractory or Relapsed Acute Lymphoblastic LeukemiaCompletedNCT01656031Phase 2Results posted
• Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic MalignanciesCompletedNCT01273766Phase 2Results posted
• T-cell Depleted Alternative Donor TransplantationTerminatedNCT00968864Phase 2Results posted
• American Ginseng Extract in Preventing Respiratory Infection and in Reducing Antibiotic Use in Patients With CLLCompletedNCT00752895Phase 2Results posted
• Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other DiseasesCompletedNCT00453206Not applicableResults posted
• CPI-613 Given With Metformin in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)WithdrawnNCT05854966Phase 2
• Preparatory Work to Assess Adherence to Oral ChemotherapyCompletedNCT02895542
• Investigating the Relationship Between Physical Function, Comorbidity and Cytogenetic Risk Group in Older Adults With Acute Myelogenous Leukemia (AML)CompletedNCT02662933Not applicable
• Investigating the Prevalence and Prognostic Importance of Polypharmacy in Adults Treated for Newly Diagnosed Acute Myelogenous Leukemia (AML)CompletedNCT02662920
• Metabolic Changes in Blood Samples From Patients With Acute Myeloid LeukemiaCompletedNCT02581917
• 6,8-Bis(Benzylthio)Octanoic Acid, Cytarabine, and Daunorubicin Hydrochloride in Treating Older Patients With Newly Diagnosed Acute Myeloid LeukemiaWithdrawnNCT02472626Phase 1/2
• CPI-613, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin LymphomaTerminatedNCT02168907Phase 1
• CPI-613 and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma or Hodgkin LymphomaCompletedNCT02168140Phase 1
• LCI-HEM-SPEC-001: Tissue Collection for Genetic Analysis of Acute Myelogenous LeukemiaCompletedNCT01999556
• Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Acute Promyelocytic LeukemiaApproved for marketingNCT01869803
• CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT01768897Phase 1
• Gemtuzumab Ozogamicin in Treating Patients With Acute Myeloid LeukemiaWithdrawnNCT01548911Phase 2
• Symptom-Adapted Physical Activity Intervention in Minimizing Physical Function Decline in Older Patients With Acute Myeloid Leukemia Undergoing ChemotherapyCompletedNCT01519596Not applicable
• Prolonged or Standard Infusion of Cefepime Hydrochloride in Treating Patients With Febrile NeutropeniaCompletedNCT01484015Phase 1
• Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for CancerCompletedNCT01053494Not applicable
• Physical Activity in Older Patients With Acute Myeloid Leukemia Undergoing ChemotherapyCompletedNCT00554489Not applicable
• Physical and Mental Assessment of Older Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT00499785
• Music in Reducing Anxiety and Pain in Adult Patients Undergoing Bone Marrow Biopsy for Hematologic Cancers or Other DiseasesCompletedNCT00376922Not applicable
• Healing Touch in Treating Patients Receiving Chemotherapy for Acute Myeloid Leukemia or Acute Lymphocytic LeukemiaCompletedNCT00321880Not applicable
• Cytarabine and Clofarabine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic LeukemiaCompletedNCT00295841Phase 1
• Denileukin Diftitox in Treating Patients With Fludarabine-Refractory B-Cell Chronic Lymphocytic LeukemiaCompletedNCT00082940Phase 2
• Sargramostim in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia Who Are Not in Complete Cytogenetic Remission Following Initial TreatmentCompletedNCT00072579Phase 2
• DTGM Fusion Protein in Treating Patients With Recurrent or Refractory Acute Myeloid LeukemiaCompletedNCT00003840Phase 1/2
• High-Intensity, Brief-Duration Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic LeukemiaCompletedNCT00002865Phase 2