Crinetics Pharmaceuticals Inc. clinical trials

Acquired by Vertex Pharmaceuticals Incorporated, Sep 1, 2026 · source ↗

The registry lists 19 studies whose lead sponsor is Crinetics Pharmaceuticals Inc.. 3 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 16, 2026.

Studies

Recruiting first, then most recently updated. Showing 19 of 19. All Vertex Pharmaceuticals Incorporated studies →

• A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)RecruitingNCT07159841Phase 2/3

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• A Study to Evaluate Atumelnant in Adults With Congenital Adrenal HyperplasiaRecruitingNCT07144163Phase 3

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• An Extension Study to Evaluate Safety and Efficacy of Atumelnant in Participants With Congenital Adrenal HyperplasiaRecruitingNCT06712823Phase 2

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine RegimenActive, not recruitingNCT07087054Phase 3

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's SyndromeCompletedNCT05804669Phase 1/2

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid TumorsActive, not recruitingNCT07129252Phase 1/2

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 in Participants With Congenital Adrenal Hyperplasia (TouCAHn)CompletedNCT05907291Phase 2

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• Drug-Drug Interaction Study of Atumelnant in Healthy ParticipantsCompletedNCT07570082Phase 1

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• A Study to Evaluate the Long-Term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)TerminatedNCT04261712Phase 2

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of AcromegalyTerminatedNCT04837040Phase 3

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (PATHFNDR-2)TerminatedNCT05192382Phase 3

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• Study to Evaluate the Safety, PK, and Dose Response of Paltusotine in Subjects With Carcinoid SyndromeCompletedNCT05361668Phase 2

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• A Study to Assess Pharmacokinetics, Safety, and Tolerability of Atumelnant in Healthy Japanese and Caucasian ParticipantsCompletedNCT07221084Phase 1

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Evolve)CompletedNCT03792555Phase 2

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• An Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Edge)CompletedNCT03789656Phase 2

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• Single and Multiple-Ascending Dose Study of CRN04894 in Healthy VolunteersCompletedNCT06048887Phase 1

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• A Single and Multiple-Ascending Dose Study of CRN01941 in Healthy Adult VolunteersCompletedNCT03936166Phase 1

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• Mass Balance and Pharmacokinetics of [14C]-CRN00808 in Healthy VolunteersCompletedNCT04246749Phase 1

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated

• Single and Multiple-Ascending Dose Study of CRN00808 in Healthy VolunteersCompletedNCT03276858Phase 1

  Sponsor listed in the registry: Crinetics Pharmaceuticals Inc. · First submitted before Crinetics Pharmaceuticals Inc. became part of Vertex Pharmaceuticals Incorporated