Vanderbilt University Medical Center: Cognitive Dysfunction trials

The registry lists 24 Cognitive Dysfunction studies with Vanderbilt University Medical Center as lead sponsor. 1 are open to participants now and 8 have results posted.

Phase 1 2Phase 2 6Phase 3 2No phase 15(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Tennessee Alzheimer's ProjectRecruitingNCT05372172
• Maximizing trEatment of Neurological Dysfunction Using INtravenous Guanfacine StudyCompletedNCT04742673Phase 2Results posted
• Early Cognitive Intervention in DeliriumCompletedNCT04740567Not applicableResults posted
• Vitamin D to Improve Outcomes by Leveraging Early Treatment: Long-term Brain Outcomes in Vitamin D Deficient PatientsCompletedNCT03733418Results posted
• Early-onset Obesity and Cognitive Impairment in Children With PseudohypoparathyroidismCompletedNCT02411461Results posted
• Nicotinic Treatment of Post-Chemotherapy Subjective Cognitive Impairment: A Pilot StudyCompletedNCT02312934Phase 2Results posted
• Nicotine Treatment of Cognitive Decline in Down SyndromeCompletedNCT01778946Phase 1/2Results posted
• The MENDS2 Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory FailureCompletedNCT01739933Phase 3Results posted
• The Modifying the Impact of ICU-Associated Neurological Dysfunction-USA (MIND-USA) StudyCompletedNCT01211522Phase 3Results posted
• Neurophysiology Biomarkers of Cognitive Impairment Associated With Deep Brain StimulationActive, not recruitingNCT05933681Not applicable
• Disclosing Dementia Risk Based on Plasma Phosphorylated TauCompletedNCT05377060Not applicable
• Vanderbilt Memory and Aging ProjectActive, not recruitingNCT05372159
• Computerized Memory Enhancing Treatment in MCICompletedNCT05332522Not applicable
• Cognitive Training in Survivors of Covid-19: A Randomized TrialCompletedNCT04956887Not applicable
• COgnitive and Physical Exercise to Improve Outcomes After Surgery (COPE-iOS) StudyActive, not recruitingNCT04889417Not applicable
• Dopaminergic Dysfunction in Late-Life DepressionCompletedNCT04469959Phase 2
• Neuroplasticity-Based Cognitive Remediation for Chemotherapy-Related Cognitive ImpairmentCompletedNCT04230863Not applicable
• Multiple Ascending Dose Putative Cognitive Enhancer VU319WithdrawnNCT04051801Phase 1
• Assessment of Cognitive and Functional Impairment in Older Patients After ERCPCompletedNCT03762954
• Memantine for the Treatment of Cognitive Impairment in Systemic Lupus ErythematosusCompletedNCT03527472Phase 2
• Measuring Outcomes of Activity in Intensive CareActive, not recruitingNCT03115840
• Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU StudyActive, not recruitingNCT03098459
• The Activity Intervention for ChemobrainCompletedNCT00495703Phase 2
• The SOMNUS Study: Sedative Optimization Via Monitoring Neurological StatusCompletedNCT00469482Not applicable