University of North Carolina, Chapel Hill: Cystic Fibrosis trials

The registry lists 20 Cystic Fibrosis studies with University of North Carolina, Chapel Hill as lead sponsor. 2 are open to participants now and 8 have results posted.

Early Phase 1 3Phase 1 2Phase 2 3Phase 4 1No phase 11(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Quantitation and Spatial Registration of Airways Dysfunction With Dynamic 19F MRI in Cystic FibrosisRecruitingNCT06057714
• Prospective Healthcare-Associated Links in Transmission of Nontuberculous MycobacteriaEnrolling by invitationNCT05686837
• Inhaled Mannitol on Mucociliary Clearance in Moderate to Severe Cystic FibrosisCompletedNCT05740618Phase 4Results posted
• STaph Aureus Resistance-Treat Early and Repeat (STAR-TER)CompletedNCT03489629Phase 2Results posted
• Researching the Effects of Airway Clearance Therapies in Cystic FibrosisCompletedNCT03078127Not applicableResults posted
• Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant SuitabilityCompletedNCT01615484Not applicableResults posted
• Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF)TerminatedNCT01349192Phase 2Results posted
• Durability of Hypertonic Saline for Enhancing Mucociliary Clearance in Cystic FibrosisCompletedNCT01094704Phase 1Results posted
• Effect of Hypertonic Saline on Mucus Clearance in Children Ages 5-12 With Cystic FibrosisCompletedNCT01031706Not applicableResults posted
• Effect of Lucinactant on Mucus Clearance in Cystic Fibrosis Lung DiseaseCompletedNCT00934362Phase 2Results posted
• 19F MRI of Ventilation in Subjects With Cystic Fibrosis Undergoing Treatment for Pulmonary ExacerbationTerminatedNCT03497117Early Phase 1
• 19F MRI to Evaluate Regional Ventilation in Healthy Subjects and Subjects With Cystic FibrosisCompletedNCT03489590Early Phase 1
• Comparison of 129Xe MRI With 19F MRI in CF Lung DiseaseCompletedNCT03482960Early Phase 1
• Initial and Chronic Methicillin Resistant Staphylococcus Aureus (MRSA) Infection in Cystic Fibrosis (CF)CompletedNCT02684422
• Phase 2 Study of Ex-vivo Perfusion and Ventilation of Lungs to Assess Transplant SuitabilityTerminatedNCT01241942Not applicable
• Molecular Phenotypes for Cystic Fibrosis Lung DiseaseCompletedNCT01116414
• Comparison of Antibiotics for Pseudomonas in Early CFCompletedNCT00823238Phase 1
• Genetic Modifiers of Cystic Fibrosis (CF) Liver DiseaseActive, not recruitingNCT00804583
• Rare Genetic Disorders of the Breathing AirwaysCompletedNCT00323167
• Gene Modifiers of Cystic Fibrosis Lung DiseaseActive, not recruitingNCT00037765