University of Florida: Brain Neoplasms trials

The registry lists 17 Brain Neoplasms studies with University of Florida as lead sponsor. 5 are open to participants now and 2 have results posted.

Phase 1 10Phase 2 2Phase 4 1No phase 5(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• IL-8 Receptor Modified Patient-Derived Activated CD70 CAR T Cell Therapy in Adults With Brain MetastasesRecruitingNCT07569263Phase 1
• IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG)Not yet recruitingNCT06946680Phase 1
• ADAGiO: Adoptive Cellular Therapy for the TreAtment of Recurrent OliGodendrogliOma (OG) Adult PatientsRecruitingNCT06254326Phase 1
• A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)RecruitingNCT04573140Phase 1
• Florida Center for Brain Tumor ResearchRecruitingNCT00811148
• 1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor PatientsCompletedNCT02334722Phase 4Results posted
• Study of Temozolomide to Treat Newly Diagnosed Brain MetastasesTerminatedNCT00717275Phase 2Results posted
• RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)Active, not recruitingNCT06389591Phase 1
• RNA Lipid Particles Targeting Pediatric Recurrent Intracranial Malignancies and Other systEmic Solid TumorsActive, not recruitingNCT05660408Phase 1/2
• IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult GlioblastomaActive, not recruitingNCT05353530Phase 1
• LITT and Pembrolizumab in Recurrent Brain MetastasisTerminatedNCT04187872Phase 1
• Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I)TerminatedNCT03396575Phase 1
• Feasibility Study of Tumor Blood Flow Measurement by Detection of Positron Activation Post Proton Therapy (DS01)TerminatedNCT01987193
• NovoTTF Therapy in Treating Patients With Recurrent Glioblastoma MultiformeTerminatedNCT01954576Not applicable
• Study of the Health Information Needs of Brain Cancer PatientsCompletedNCT01130220
• Study of the Safety and Efficacy of Dichloroacetate (DCA) in Glioblastoma and Other Recurrent Brain TumorsCompletedNCT01111097Phase 1
• Outcomes Study of Late Effects After Proton RT for Pediatric Tumors of the Brain, Head, and NeckCompletedNCT01067196