University Health Network, Toronto: Depressive Disorder trials

The registry lists 21 Depressive Disorder studies with University Health Network, Toronto as lead sponsor. 1 are open to participants now and 1 have results posted.

Early Phase 1 1Phase 1 1Phase 2 4Phase 3 7Phase 4 1No phase 8(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Brain Insulin Resistance in Mood DisordersRecruitingNCT03915613Phase 1/2
• 12-Week Study Evaluating the Efficacy, Safety, and Tolerability of Adjunctive Infliximab for Bipolar I/II DepressionCompletedNCT02363738Phase 2Results posted
• Treatment of Bipolar Depression With PentoxifyllineCompletedNCT04417049Early Phase 1
• Repetitive Transcranial Magnetic Stimulation Trajectory of Outcomes StudyStatus unknownNCT04376697Not applicable
• Canadian Biomarker Integration Network for Depression (CAN-BIND) - Validation StudyCompletedNCT04162522Phase 3
• Dorsomedial rTMS For Depression In Borderline Personality DisorderStatus unknownNCT03472638Not applicable
• Study of Ketamine for Depression in Cancer Patients Receiving Palliative CareCompletedNCT03410446Phase 2
• Examining the Efficacy of Orbitofrontal Cortex rTMS for DepressionCompletedNCT02797210Not applicable
• Comparing Different Patterns of rTMS in Major DepressionStatus unknownNCT02778035Not applicable
• High-frequency vs. Low-frequency vs. Sham DMPFC-rTMS for Major DepressionStatus unknownNCT02702154Not applicable
• Treating Major Depressive Disorder With Music and Low-frequency Rhythmic Sensory StimulationCompletedNCT02685982Not applicable
• Cognitive Dysfunction and Glucagon-like Peptide-1 AgonistsCompletedNCT02423824Phase 3
• Canadian Biomarker Integration Network for Depression StudyCompletedNCT01655706Phase 3
• Evaluating the Efficacy of Adjunctive Minocycline for the Treatment of Bipolar DepressionCompletedNCT01403662Phase 3
• Effect of Intranasal Insulin on Depressive Symptoms in Major Depressive DisorderCompletedNCT00570050Phase 3
• Sedating Antidepressant Improves Driving Safety in Patients With Major Depressive DisorderCompletedNCT00385437Phase 2
• Memory Functioning and Antidepressant TreatmentCompletedNCT00296933Phase 3
• Deep Brain Stimulation for Refractory Major DepressionCompletedNCT00296920Phase 3
• Testosterone and Major DepressionCompletedNCT00286546
• A Neuroimaging Investigation of Brain Activity in Major Depressive Disorder and Bipolar DisorderCompletedNCT00188942Phase 4
• Effect of the Menstrual Cycle on the Symptoms of Depression and Treatment ResponseCompletedNCT00188396Not applicable