University Health Network, Toronto: Carcinoma, Hepatocellular trials

The registry lists 19 Carcinoma, Hepatocellular studies with University Health Network, Toronto as lead sponsor. 5 are open to participants now and 1 have results posted.

Phase 1 2Phase 2 9Phase 4 1No phase 8(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study of Standard Of Care Versus Radio Ablation in Early Stage HCCRecruitingNCT07628751Not applicable
• Using Radiotherapy and Immunotherapy to Treat Advanced Liver Cancer Before TransplantRecruitingNCT06725121Phase 1/2
• Durvalumab and Tremelimumab in Resectable HCCRecruitingNCT05440864Phase 2
• LANDscape MApping of Epitopes and T Cell Receptors for Selected CancersRecruitingNCT04665388
• Cabozantinib to Treat Recurrent Liver Cancer Post TransplantRecruitingNCT04204850Phase 2
• Study of Pembrolizumab and Radiotherapy in Liver CancerTerminatedNCT03316872Phase 2Results posted
• Blood Salvage in Orthotopic Liver Transplantation With HCCActive, not recruitingNCT05612477Not applicable
• Long-term Outcomes of Ablation, Liver Resection, and Liver Transplant as First-line Treatment for Solitary HCC of 3 cm or LessCompletedNCT05193253
• An Exploratory Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma and Non-Small Cell Lung Cancer With Liver Metastases (INTEGRATE)Active, not recruitingNCT04563338Phase 2
• Relationship Between 18FDG PET/MRI Patterns and ctDNA to Predict HCC Recurrence After Liver TransplantationActive, not recruitingNCT03839706Not applicable
• Evaluation of Gd-EOB-DTPA MRI for Detection and Characterization of Liver Nodules in Cirrhotic Patients Undergoing Liver Transplantation and Potential Impact on Transplant EligibilityStatus unknownNCT03342677Not applicable
• Radiotherapy Versus no Intervention in Adult Patients With Hepatocellular Carcinoma Not Eligible for Transarterial Chemoembolization or Ablation Prior to Liver Transplant (RADBRI)WithdrawnNCT03172559Not applicable
• Pharmacological Manipulation of Intrahepatic Arterial Blood Flow in HCCCompletedNCT02472249Phase 4
• Study of Axitinib in Patients With Unresectable Hepatocellular CarcinomaCompletedNCT01334112Phase 2
• Non-invasive Prediction of Microvascular Invasion in Hepatocellular Carcinoma by Blood-Oxygen-Level Dependent Magnetic Resonance Imaging (BOLD MRI)CompletedNCT00963612Not applicable
• Palliative Radiotherapy (RT) for Liver Metastases (Mets) and Hepatocellular Carcinoma (HCC)(COLD 4)CompletedNCT00923897Phase 2
• Stereotactic Body Radiation Therapy (SBRT) Hepatocellular Carcinoma (COLD 2)CompletedNCT00914355Phase 2
• Sorafenib-RT in Treating Hepatocellular Carcinoma (SHEP)CompletedNCT00892658Phase 1
• Oblimersen and Doxorubicin in Treating Patients With Advanced Hepatocellular Carcinoma (Liver Cancer)CompletedNCT00047229Phase 2