University Health Network, Toronto: Carcinoma trials

The registry lists 35 Carcinoma studies with University Health Network, Toronto as lead sponsor. 3 are open to participants now and 2 have results posted.

Early Phase 1 2Phase 1 8Phase 2 17Phase 4 1No phase 9(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Using Tumor Models to Determine TreatmentsRecruitingNCT06813079Phase 2
• Using Radiotherapy and Immunotherapy to Treat Advanced Liver Cancer Before TransplantRecruitingNCT06725121Phase 1/2
• Durvalumab and Tremelimumab in Resectable HCCRecruitingNCT05440864Phase 2
• A Phase I/Ib Study of MEK162, a MEK Inhibitor, in Combination With Carboplatin and Pemetrexed in Patients With Non-squamous Carcinoma of the LungCompletedNCT02185690Phase 1Results posted
• A Study of ENMD-2076 in Ovarian Clear Cell CancersCompletedNCT01914510Phase 2Results posted
• Study of Circulating Tumor DNA (ctDNA) Kinetics in Immuno-oncology (IO-KIN)CompletedNCT04606940
• A Multi-Cancer, Multi-State, Platform Study of Durvalumab (MEDI4736) and Oleclumab (MEDI9447) in Pancreatic Adenocarcinoma, Non-Small Cell Lung Cancer and Squamous Cell Carcinoma of the Head and Neck to Correlate Clinical, Molecular and Immunologic Parameters With DNA MethylationWithdrawnNCT04262388Phase 2
• Renal Cell Carcinoma Microenvironment Discovery ProjectCompletedNCT04005183
• Relationship Between 18FDG PET/MRI Patterns and ctDNA to Predict HCC Recurrence After Liver TransplantationActive, not recruitingNCT03839706Not applicable
• Sitravatinib (MGCD516) and Nivolumab in Oral Cavity Cancer Window Opportunity StudyCompletedNCT03575598Early Phase 1
• Transoral Robotic Surgery and Tailored Radiotherapy in Unknown Primary and Small Squamous Cell Head and Neck CancerCompletedNCT03281499Not applicable
• A Superiority Trial to Compare Re-resection of High-grade T1 Bladder Urothelial Carcinoma to no Re-resection for Improving Progression Free SurvivalTerminatedNCT03266900Early Phase 1
• Radiotherapy Versus no Intervention in Adult Patients With Hepatocellular Carcinoma Not Eligible for Transarterial Chemoembolization or Ablation Prior to Liver Transplant (RADBRI)WithdrawnNCT03172559Not applicable
• Pre-operative Mocetinostat (MGCD0103) and Durvalumab (MEDI4736) (PRIMED) for Squamous Cell Carcinoma of the Oral CavityWithdrawnNCT02993991Phase 1
• Detection and Localization of Carcinoma Using High Resolution Transrectal Imaging - Proof of Concept StudyCompletedNCT02786459Not applicable
• Phase I Study of BYL719 in Combination With Cisplatin and Radiotherapy in Patients With Squamous Cell Head and Neck CancerCompletedNCT02537223Phase 1
• Pharmacological Manipulation of Intrahepatic Arterial Blood Flow in HCCCompletedNCT02472249Phase 4
• The Potential for Metformin to Improve Tumor Oxygenation in Locally Advanced Cervix Cancer: A Phase II Randomized TrialCompletedNCT02394652Phase 2
• A Study of MEK162 With Gemcitabine and Oxaliplatin in Biliary CancerWithdrawnNCT02105350Phase 1
• Dacomitinib Plus Radiotherapy, With and Without Cisplatin in Patients With Squamous Cell Carcinoma of the Head and NeckCompletedNCT01737008Phase 1
• A Study of PF-00299804 When Given Through a Feeding Tube in Locally Advanced Head and Neck Squamous Cell CarcinomaCompletedNCT01484847Not applicable
• Study of Axitinib in Patients With Unresectable Hepatocellular CarcinomaCompletedNCT01334112Phase 2
• Efficacy of Ultrasound Contrast Agent to Assess Renal MassesCompletedNCT01062178Phase 2
• Non-invasive Prediction of Microvascular Invasion in Hepatocellular Carcinoma by Blood-Oxygen-Level Dependent Magnetic Resonance Imaging (BOLD MRI)CompletedNCT00963612Not applicable
• Palliative Radiotherapy (RT) for Liver Metastases (Mets) and Hepatocellular Carcinoma (HCC)(COLD 4)CompletedNCT00923897Phase 2
• Stereotactic Body Radiation Therapy (SBRT) Hepatocellular Carcinoma (COLD 2)CompletedNCT00914355Phase 2
• Sorafenib-RT in Treating Hepatocellular Carcinoma (SHEP)CompletedNCT00892658Phase 1
• A Study of Sunitinib in Recurrent and/or Metastatic Adenoid Cystic Carcinoma of the Salivary GlandsCompletedNCT00886132Phase 2
• Study of Sorafenib and Palliative Radiotherapy in Kidney Cancer That Spreads to the BoneCompletedNCT00609934Phase 1/2
• A Study of Neoadjuvant Sutent for Patients With Renal Cell CarcinomaTerminatedNCT00480935Phase 2
• Pre-operative Administration of Sorafenib in Patients With Metastatic Renal Cell Carcinoma Undergoing Kidney RemovalCompletedNCT00480389Phase 2
• Ultrasound Biomicroscopy - ApoptosisCompletedNCT00188370Phase 2
• Hardwins - Squamous Cell Carcinoma Head & Neck (Surgery/RT)CompletedNCT00188318Phase 2
• Positron Emission Tomography Scanning and Epstein-Barr Virus DNA Levels in the Staging and Follow-up of Nasopharyngeal Carcinoma.CompletedNCT00188253
• Oblimersen and Doxorubicin in Treating Patients With Advanced Hepatocellular Carcinoma (Liver Cancer)CompletedNCT00047229Phase 2