U.S. Army Medical Research and Development Command: Leishmaniasis trials

The registry lists 16 Leishmaniasis studies with U.S. Army Medical Research and Development Command as lead sponsor. 0 are open to participants now and 14 have results posted.

Phase 1 1Phase 2 10Phase 3 2No phase 4(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Evaluation of CL Detect™ Rapid Test to Detect Cutaneous LeishmaniasisCompletedNCT01865032Results posted
• Phase 3 Study of Walter Reed (WR) 279,396 and Paromomycin Alone for the Treatment of Cutaneous Leishmaniasis in PanamaCompletedNCT01790659Phase 3Results posted
• Evaluation of a Rapid Diagnostic Device, CL Detect, for the Diagnosis of Cutaneous Leishmaniasis in TunisiaCompletedNCT01769612Results posted
• A Study to Evaluate the Efficacy and Tolerance of WR279,396 for Old World Cutaneous LeishmaniasisCompletedNCT01536795Phase 2Results posted
• WR 279,396 Open Label Treatment Protocol in TunisiaTerminatedNCT01494350Phase 2Results posted
• Safety, Efficacy, and PK of Topical Paromomycin/Gentamicin Cream for Treatment of Cutaneous LeishmaniasisTerminatedNCT01140191Phase 2Results posted
• Pharmacokinetics, Safety, and Efficacy Trial of WR 279,396 (Paromomycin + Gentamicin Topical Cream) and Paromomycin Topical Cream for the Treatment of Cutaneous Leishmaniasis in PanamaCompletedNCT01083576Phase 2Results posted
• Safety, Efficacy and Pharmacokinetics (PK) Study of WR 279,396 Versus Paromomycin for Treatment of Cutaneous Leishmaniasis (Peru-PK)CompletedNCT01032382Phase 2Results posted
• Local Heat Therapy Versus Sodium Stibogluconate for the Treatment of Cutaneous LeishmaniasisCompletedNCT00884377Phase 2Results posted
• Topical Treatment of Cutaneous Leishmaniasis With WR 279,396: A Phase 2 Study in the Old WorldCompletedNCT00703924Phase 2Results posted
• Sodium Stibogluconate Treatment of LeishmaniasisCompletedNCT00662012Phase 2Results posted
• Topical Treatment of Recalcitrant Ulcerative Old World Leishmaniasis With WR 279,396TerminatedNCT00657917Phase 2Results posted
• Use of Sodium Stibogluconate as a Treatment for LeishmaniasisCompletedNCT00657618Phase 1/2Results posted
• Phase 3 Study to Evaluate WR 279,396 vs. Paromomycin Alone to Treat Cutaneous Leishmaniasis (in Tunisia)CompletedNCT00606580Phase 3Results posted
• Paromomycin for Individuals With Uncomplicated Cutaneous LeishmaniasisNo longer availableNCT01641796
• Cosmetic Outcome of Leishmaniasis Scar After WR279396 ApplicationCompletedNCT00490230Not applicable