Tongji Hospital: Carcinoma, Hepatocellular trials

The registry lists 27 Carcinoma, Hepatocellular studies with Tongji Hospital as lead sponsor. 19 are open to participants now and 0 have results posted.

Phase 1 1Phase 2 6Phase 3 3Phase 4 1No phase 17(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Multimodalomics-based Construction of Spatiotemporal Characteristics of Dynamic Liver Cancer Microenvironment to Characterize the Clinical Application of Immune Mechanisms in Liver CancerRecruitingNCT07838415
• AI-Guided Surveillance and Curative Salvage of Recurrence After Hepatocellular Carcinoma Resection or AblationNot yet recruitingNCT07732504Not applicable
• Denosumab Strategy for Liver Cancer With Bone MetastasesNot yet recruitingNCT07537972Phase 2
• Surgery Plus Systemic Therapy for Liver Cancer With Extrahepatic MetastasesNot yet recruitingNCT07537959Not applicable
• Local Consolidation After Sintilimab Plus Lenvatinib for Metastatic Liver CancerNot yet recruitingNCT07537946Phase 3
• A Clinical Trial of Firsekibart, Tislelizumab, and Lenvatinib in Patients With Unresectable, TP53-Mutated Hepatocellular CarcinomaNot yet recruitingNCT07535840Not applicable
• GNB4 and Riplet Gene Methylation Combined Detection Kit for Hepatocellular Carcinoma Recurrence MonitoringNot yet recruitingNCT07489768
• Tislelizumab Combined With Huaier Granule as First-line Treatment for Unresectable Hepatocellular CarcinomaRecruitingNCT07413354Phase 2
• Multimodal Deep Learning for Postoperative Liver Cancer Risk Stratification and InterventionRecruitingNCT07282184Phase 1/2
• A Prospective Observational Cohort Study on Dynamic CD8+ T-cell Profiling and Multi-omics Biomarkers for Predicting Conversion Therapy Response in Unresectable Hepatocellular CarcinomaNot yet recruitingNCT07117279
• Tauroursodeoxycholic Acid Combined With PD-1/PD-L1 Immunotherapy in Advanced Hepatocellular Carcinoma: A Prospective StudyNot yet recruitingNCT07064668Phase 2
• Iparomlimab and Tuvonralimab as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma With High Risk of RecurrenceRecruitingNCT06954116Phase 2
• Circulating Tumor Mitochondrial DNA (ct-mtDNA) As a Biomarker for Hepatocellular Carcinoma Recurrence SurveillanceRecruitingNCT06653062
• Donafenib Combined With Immunotherapy and Local Therapy for Unresectable Hepatocellular Carcinoma That Has Failed in Previous TherapyNot yet recruitingNCT06496815Phase 4
• HAIC, Lenvatinib, and Cadonilimab as Conversion Therapy for Initially Unresectable Hepatocellular CarcinomaRecruitingNCT06187961Phase 2
• A Study to Evaluate Sintilimab Plus Lenvatinib as Adjuvant Therapy in Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis (PVTT) After Surgical ResectionNot yet recruitingNCT06089382Phase 3
• Postoperative Adjuvant Sintilimab in Hepatocellular Carcinoma With Microvascular InvasionNot yet recruitingNCT06089369Phase 3
• Combined TACE, TKI/Anti-VEGF and ICIs as Conversion Therapy for Advanced Hepatocellular CarcinomaRecruitingNCT05717738
• PVE/PVL Combined With DEB-TACE in the Treatment of Patients With Large and Unresectable Liver CancerRecruitingNCT05103007Not applicable
• Prospective Evaluation of a Locked Risk-Stratified Surveillance Strategy for Extrahepatic Metastasis in Hepatocellular CarcinomaActive, not recruitingNCT07444905
• Precision Recurrence Risk Assessment in Early-stage Hepatocellular CarcinomaCompletedNCT07030842
• A Multicenter, Prospective Study of Perioperative Finotonlimab Combined With Bevacizumab in Resectable Hepatocellular Carcinoma Patients With High-Risk Factors for RecurrenceActive, not recruitingNCT07009470Not applicable
• Real-world Study of Efficacy and Safety of ICIs and TKIs Therapy for HCCStatus unknownNCT05420922
• Circulating Tumor Cell Detection in Hepatocellular CarcinomaCompletedNCT05297955
• Clinical Study on BIFICO Accelerating Postoperative Liver Function Recovery in Patients With Hepatocellular CarcinomaCompletedNCT05178524Not applicable
• The Effect of Gut Microbiota on Postoperative Liver Function Recovery in Patients With Hepatocellular CarcinomaCompletedNCT04303286
• Trans-parenchymal Compressing Suture in Major Liver ResectionCompletedNCT03215290Not applicable