The University of Texas Health Science Center at San Antonio: Diabetes Mellitus, Type 2 trials

The registry lists 38 Diabetes Mellitus, Type 2 studies with The University of Texas Health Science Center at San Antonio as lead sponsor. 8 are open to participants now and 17 have results posted.

Early Phase 1 3Phase 1 4Phase 3 5Phase 4 13No phase 13(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• SGLT2i, Pioglitazone, and Ketone Production in T2DRecruitingNCT07053319Phase 1
• SGLT2i, Ketoacidosis, Volume Contraction, and InsulinopeniaRecruitingNCT07053306Phase 1
• SGLT2i, Hepatic Glucose Production, and SNSRecruitingNCT07053293Early Phase 1
• Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset DiabetesRecruitingNCT06246799Phase 3
• Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and DiabetesRecruitingNCT06108076Early Phase 1
• SGLTi, Hepatic Glucose Production and KetogenesisRecruitingNCT05960656Phase 1
• Quantifying Hepatic Mitochondrial Fluxes in HumansRecruitingNCT05305287Phase 4
• Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)RecruitingNCT02969798Not applicable
• Effect of GLP1 Receptor Agonists on Physical Function, Body Composition, and Markers of Aging in Older AdultsCompletedNCT05786521Phase 4Results posted
• Ketones, Muscle Metabolism, and SGLT2 Inhibitors - Protocol 1CompletedNCT03560323Phase 1Results posted
• Can Exenatide Prevent Increase in EGP in Response to Dapagliflozin-induced Increase in GlucosuriaCompletedNCT03331289Phase 4Results posted
• PROTOCOL 3: Role of the Renal Nerves in the Increase in EGP in Response to GlucosuriaCompletedNCT03168295Phase 4Results posted
• Paradoxical Stimulation of Hepatic Glucose Production With DapagliflozinCompletedNCT02984644Phase 3Results posted
• Effect of Dapagliflozin on Hepatic and Renal Glucose Metabolism SubjectsCompletedNCT02981966Phase 4Results posted
• Effect of Chronic Exenatide Therapy on Beta Cell Function and Insulin Sensitivity in T2DMCompletedNCT02981069Phase 4Results posted
• Effect of Farxiga on Renal Function and Size in Type 2 Diabetic Patients With HyperfiltrationCompletedNCT02911792Phase 4Results posted
• ESR-15-11293 - Saxa/Dapa, Safety and Efficacy StudyCompletedNCT02613897Not applicableResults posted
• SGLT2 Inhibition and Stimulation of Endogenous Glucose Production: Protocol 2CompletedNCT02592421Phase 3Results posted
• Effect of Combined Incretin-Based Therapy Plus Canagliflozin on Glycemic Control and the Compensatory Rise in Hepatic Glucose Production in Type 2 Diabetic PatientsCompletedNCT02324842Not applicableResults posted
• Effect of Cycloset on Glycemic Control When Added to Glucagon-like Peptide 1 (GLP-1) Analogue TherapyCompletedNCT02299050Phase 4Results posted
• Myocardial Dysfunction in Type 2 Diabetes Mellitus (T2DM)CompletedNCT01588470Phase 4Results posted
• Effect of Pioglitazone on TIMP-3 and TACE in Type 2 DiabetesCompletedNCT01223196Phase 4Results posted
• Comparative Study of Implant Surfaces to Enhance Stabilization in Patients With Type 2 DiabetesCompletedNCT01142297Not applicableResults posted
• Effect of Pioglitazone and Exenatide on Body Weight and Beta Cell FunctionCompletedNCT00845182Phase 4Results posted
• Actos Now for Prevention of Diabetes (ACT NOW)CompletedNCT00220961Phase 3Results posted
• Lifestyle MIND- Feasibility of Wait-list ControlWithdrawnNCT06384521Not applicable
• Multilevel Lifestyle Intervention to Improve Physical Function in Older Adults With Type 2 DiabetesCompletedNCT06173804Not applicable
• Effect of Novel Glucagon Receptor Antagonist REMD-477 on Glucose and Adipocyte Metabolism in T2DMCompletedNCT05093517Early Phase 1
• Metabolism of Low Carbohydrate and Ketogenic DietCompletedNCT05071287Not applicable
• Effect of Ketogenic Diet on Glucose Metabolism and Energy Expenditure in Type 2 DiabetesCompletedNCT04791787Not applicable
• Personalized Behavioral Nutrition Intervention in Older AAs With T2DCompletedNCT04533659Not applicable
• Effects of Canagliflozin on Intravascular Volume and HemodynamicsWithdrawnNCT03190798Phase 4
• Diabetes Effects on Long-Term Implant Survival and SuccessCompletedNCT02282046
• A Brief Intervention to Improve Medication Knowledge and Adherence Among Family Medicine Patients in South TexasCompletedNCT00846300Not applicable
• Molecular Mechanisms of Type 2 Diabetes MellitusCompletedNCT00816218Phase 4
• Acute Metabolic Effects of LAF 237 in Type 2 DiabeticsCompletedNCT00230464Phase 3
• Incidence of Diabetes and Cardiovascular Disease in Mexican AmericansCompletedNCT00005205
• Diabetes and Cardiovascular Risk In Mexico City (San Antonio Heart Study)CompletedNCT00005146