The Netherlands Cancer Institute: Breast Neoplasms trials

The registry lists 40 Breast Neoplasms studies with The Netherlands Cancer Institute as lead sponsor. 13 are open to participants now and 0 have results posted.

Phase 1 4Phase 2 15Phase 3 12No phase 13(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• DiEtary Mimicry by Glucocorticoid Modulation Evaluation in ER+ Metastatic Breast Cancer Treatment: Efficacy and Response (DEMETER Trial)Not yet recruitingNCT07786051Phase 2
• Pembrolizumab Adjuvant in Patients With Early-stage Triple Negative Breast Cancer With Residual Disease After Neoadjuvant Pembrolizumab Plus ChemotherapyNot yet recruitingNCT07486687Phase 3
• Contrast-enhanced Ultrasound for Sentinel Node DetectionRecruitingNCT07310758Phase 2/3
• TAO-Towards Optimal (Neo)Adjuvant Systemic Therapy of Stage III Triple-negative Breast CancerRecruitingNCT06931769
• OPTImaL:Optimisation of Treatment for Patients With Low Stage Triple-negative Breast Cancer With High Stromal Tumor-infiltrating LymphocytesRecruitingNCT06476119
• Preoperative Accelerated Partial Breast Irradiation in Patients With Locally Recurrent or Second Primary Breast CancerRecruitingNCT06362616Not applicable
• NOvel Immunotherapy Strategies for Advanced Triple Negative Breast Cancer (TNBC) Patients: TONIC-3 TrialRecruitingNCT06342037Phase 2
• Chemosensitivity During Phases of the Menstrual Cycle in Breast Cancer PatientsRecruitingNCT06273800Not applicable
• Neoadjuvant Trastuzumab, Pertuzumab and Tucatinib Without Chemotherapy in HER2-positive Breast Cancer: the TRAIN-4 StudyRecruitingNCT06162559Phase 1
• Radioembolisation and Chemotherapy in Liver Metastatic Breast Cancer PatientsRecruitingNCT06142344Not applicable
• Avoiding Sentinel Lymph Node Biopsy in Breast Cancer Patients After Neoadjuvant ChemotherapyNot yet recruitingNCT04225858Not applicable
• Immune Induction Strategies to Improve Response to Immune Checkpoint Blockade in Triple Negative Breast Cancer (TNBC) PatientsRecruitingNCT04159818Phase 2
• Pre-operative Trial for Breast Cancer With Nivolumab in Combination With Novel IORecruitingNCT03815890Phase 2
• Ultrasound-guided Erector Spinae Plane Block Versus Paravertebral Block in Breast Cancer Patients Undergoing Mastectomy With Immediate Reconstruction - a Non-inferiority TrialStatus unknownNCT05590559Not applicable
• Monalizumab and Trastuzumab In Metastatic HER2-pOSitive breAst Cancer: MIMOSA-trialCompletedNCT04307329Phase 2
• The SONImage StudyActive, not recruitingNCT04125277Not applicable
• AssessinG Efficacy of Carboplatin and ATezOlizumab in Metastatic Lobular Breast CancerTerminatedNCT03147040Phase 2
• The Development of a Personalized Decision Aid: Perspectives of Patients and Health Care Professionals on Shared Decision Making and Informational Needs on Radiotherapy for Breast CancerCompletedNCT02934126
• Carboplatin-cyclophosphamide Combined With AtezolizumabCompletedNCT02914470Phase 1
• Pre- Versus Postoperative Accelerated Partial Breast IrradiationTerminatedNCT02913729Not applicable
• A Feasibility Study of Niraparib for Advanced, BRCA1-like, HER2-negative Breast Cancer PatientsTerminatedNCT02826512Phase 2
• Substantially Improving the Cure Rate of High-risk BRCA1-like Breast CancerActive, not recruitingNCT02810743Phase 3
• Internet-based Cognitive Behavioral Therapy for Breast Cancer Patients With Climacteric SymptomsCompletedNCT02672189Phase 3
• Nivolumab After Induction Treatment in Triple-negative Breast Cancer (TNBC) PatientsActive, not recruitingNCT02499367Phase 2
• Identifying Subgroups With High Cardiovascular Risk in Breast Cancer SurvivorsStatus unknownNCT02485626
• Phase I of Carboplatin-Olaparib Followed by Olaparib Monotherapy in Advanced CancerCompletedNCT02418624Phase 1
• Olaparib and Radiotherapy in Inoperable Breast CancerCompletedNCT02227082Phase 1
• RCT of an Internet-based CBT Program for Sexuality and Intimacy Problems in Women Treated for Breast CancerCompletedNCT02091765Phase 3
• Neoadjuvant Chemotherapy in HER2 Positive Breast Cancer, TRAIN-2Active, not recruitingNCT01996267Phase 3
• Triple-B Study;Carboplatin-cyclophosphamide Versus Paclitaxel With or Without Atezolizumab as First-line Treatment in Advanced Triple Negative Breast CancerActive, not recruitingNCT01898117Phase 2
• High Dose Chemotherapy in Oligo-metastatic Homologous Recombination Deficient Breast CancerActive, not recruitingNCT01646034Phase 3
• Neo Adjuvant Chemotherapy in Triple Negative Breast CancerActive, not recruitingNCT01057069Phase 2/3
• Radiation Therapy Followed by Surgery in Treating Patients With Early-Stage Breast CancerCompletedNCT01024582Not applicable
• Effects of Rapid Genetic Counseling and Testing in Newly Diagnosed Breast Cancer PatientsCompletedNCT00783822Not applicable
• Trastuzumab in a Neo-adjuvant Regimen for HER2+ Breast Cancer - the TRAIN StudyCompletedNCT00768859Phase 2
• Pre-operative Hormonal Treatment for Hormone Receptor Positive Breast CancerSuspendedNCT00738777Phase 2
• Second-line Endocrine Treatment Followed by Capecitabine Versus Capecitabine Followed by Endocrine Treatment in Patients With Metastatic ER Positive Breast CancerTerminatedNCT00684216Phase 2/3
• Cognitive Behavioral Therapy (CBT) and Physical Exercise for Climacteric Symptoms in Breast Cancer Patients Experiencing Treatment-Induced Menopause: a Multicenter Randomized TrialStatus unknownNCT00582244Phase 3
• Intensified IAA With PBPC Support in Breast Tumors With Evidence of a HRDTerminatedNCT00448266Phase 2/3
• Radiation Dose Intensity Study in Breast Cancer in Young WomenActive, not recruitingNCT00212121Phase 3