SWOG Cancer Research Network: Multiple Myeloma trials

The registry lists 17 Multiple Myeloma studies with SWOG Cancer Research Network as lead sponsor. 1 are open to participants now and 5 have results posted.

Phase 2 8Phase 3 5No phase 4(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable TreatmentRecruitingNCT05561387Phase 3
• S1304, Carfilzomib and Dexamethasone for Treating Patients With Relapsed or Refractory MyelomaCompletedNCT01903811Phase 2Results posted
• S0417 Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple MyelomaTerminatedNCT00124579Phase 2Results posted
• S0115, High-Dose Melphalan and Autologous Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma or Primary Systemic AmyloidosisCompletedNCT00064337Phase 2Results posted
• S0232 Dexamethasone With or Without Lenalidomide in Treating Patients With Previously Untreated Stage I, Stage II, or Stage III Multiple MyelomaCompletedNCT00064038Phase 3Results posted
• S0204 Thalidomide, Chemotherapy, and Peripheral Stem Cell Transplant in Treating Patients With Multiple MyelomaCompletedNCT00040937Phase 2Results posted
• S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy DurationActive, not recruitingNCT04071457Phase 3
• S0833, Bortezomib, Thalidomide, Lenalidomide, Combination Chemotherapy, and Autologous Stem Cell Transplant in Treating Patients With Newly Diagnosed Multiple MyelomaWithdrawnNCT01055301Phase 2
• S0309, Repository: Blood/Bone Marrow From Pts. With Myeloma, WM, Amyloidosis, or MGUS.CompletedNCT00919139
• S0120, Studying Blood and Bone Marrow Samples From Patients With Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, or PlasmacytomaCompletedNCT00900263
• S0334 Analyzing Chromosomes in Patients With Newly Diagnosed Multiple Myeloma or Other Blood DiseaseCompletedNCT00898066
• S0702: Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid for Bone MetastasesCompletedNCT00874211
• S0340 MRI and Fludeoxyglucose F18 PET in Diagnosing Solitary PlasmacytomaTerminatedNCT00109889Phase 2
• S9922 Combination Chemo Plus Filgrastim With or Without Thalidomide in Refractory Multiple MyelomaTerminatedNCT00005834Phase 3
• S9628 Dexamethasone Plus Interferon Alfa in Treating Patients With Primary Systemic AmyloidosisCompletedNCT00002849Phase 2
• SWOG-9239 Reduction of Immunosuppression Plus Interferon Alfa and Combination Chemotherapy in Treating Patients With Malignant Tumors That Develop After Organ TransplantCompletedNCT00002657Phase 2
• SWOG-9321 Melphalan, TBI, and Transplant vs Combo Chemo in Untreated MyelomaCompletedNCT00002548Phase 3