St. Jude Children's Research Hospital: Glioma trials

The registry lists 12 Glioma studies with St. Jude Children's Research Hospital as lead sponsor. 1 are open to participants now and 1 have results posted.

Phase 1 8Phase 2 2No phase 3(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS TumorsRecruitingNCT06528691Phase 2
• Erlotinib and Radiation Therapy in Treating Young Patients With Newly Diagnosed GliomaCompletedNCT00124657Phase 1/2Results posted
• Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS TumorsActive, not recruitingNCT05835687Phase 1
• Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade GliomaActive, not recruitingNCT04065776Not applicable
• Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline GliomasCompletedNCT03696355Phase 1
• SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain TumorsCompletedNCT03434262Phase 1
• Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)CompletedNCT01644773Phase 1
• PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade GliomaCompletedNCT01393912Phase 1
• Clinical Trial Evaluating the Combination of Vandetanib and Dasatinib During and After Radiation Therapy (RT) in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG)CompletedNCT00996723Phase 1
• DNA Analysis of Tumor Tissue Samples From Patients With Diffuse Brain Stem GliomaCompletedNCT00899834
• Study of Stored Tumor Samples in Young Patients With Brain TumorsTerminatedNCT00897286
• Vandetanib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Diffuse Brainstem GliomaCompletedNCT00472017Phase 1