St. Jude Children's Research Hospital: Anemia, Sickle Cell trials

The registry lists 42 Anemia, Sickle Cell studies with St. Jude Children's Research Hospital as lead sponsor. 15 are open to participants now and 6 have results posted.

Phase 1 5Phase 2 9Phase 3 1No phase 27(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Universal Newborn Screening For Sickle Cell Disease In MozambiqueNot yet recruitingNCT07719972Not applicable
• Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell DiseaseRecruitingNCT07616154Phase 2
• Functional Ovarian Reserve in Sickle Cell DiseaseRecruitingNCT07392216
• Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell DiseaseRecruitingNCT07226219Phase 1
• Transcranial Photobiomodulation Treatment in Patients With Sickle Cell DiseaseNot yet recruitingNCT06797583Not applicable
• Gene Editing For Sickle Cell DiseaseRecruitingNCT06506461Phase 1
• Peripheral Arterial Tonometry and Neurocognition in Sickle Cell DiseaseRecruitingNCT06477289
• SCD Stem Cell Mobilization and Apheresis Using MotixafortideRecruitingNCT06442761Phase 1
• School Readiness Intervention for Preschool Children With Sickle Cell DiseaseRecruitingNCT06367192Not applicable
• Gene Therapy Communication: Use of a Needs Assessment to Drive Decision-AIDS for Gene Therapy for Rare Diseases (GENETX)RecruitingNCT05810181
• Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PETRecruitingNCT05583721Phase 2
• Sickle Cell Disease and the Genomic and Gene Therapy Needs of StakeholdersRecruitingNCT04416178
• Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell DiseaseRecruitingNCT03353584Not applicable
• Investigation of the Genetics of Hematologic DiseasesRecruitingNCT02720679
• Sickle Cell Clinical Research and Intervention ProgramRecruitingNCT02098863
• Integration of mHEALTH Into the Care of Patients With Sickle Cell Disease to Increase Hydroxyurea UtilizationCompletedNCT04080167Not applicableResults posted
• Hydroxyurea Therapy: Optimizing Access in Pediatric Populations EverywhereTerminatedNCT03825341Phase 2Results posted
• Hydroxyurea Management in Kids: Intensive Versus Stable Dosage StrategiesCompletedNCT03020615Phase 2Results posted
• Pain Management in Children and Young Adults With Sickle Cell DiseaseCompletedNCT01954927Phase 2Results posted
• Trial of Oral Glutamine in Patients With Sickle Cell AnemiaTerminatedNCT00131508Phase 2Results posted
• Stroke With Transfusions Changing to HydroxyureaTerminatedNCT00122980Phase 3Results posted
• Peripheral Blood Stem Cell Collection From Patients With Sickle Cell Disease (SCD) Using PlerixaforWithdrawnNCT04817345Phase 2
• Reduced Intensity Transplantation for Severe Sickle Cell DiseaseActive, not recruitingNCT04362293Phase 2
• Exploring Adherence Monitoring in Sickle Cell DiseaseActive, not recruitingNCT03708731
• Predictors and Outcomes in Patients With Sickle Cell DiseaseCompletedNCT03431935
• Re-Aiming at Hydroxyurea Adherence for Sickle Cell With mHealthCompletedNCT03344900
• A New Reagent Assay Examining Natural Parvovirus B19 Infection in Sickle Cell DiseaseCompletedNCT02261480
• Working Memory and School Readiness in Preschool-Aged Children With Sickle Cell DiseaseCompletedNCT02227472
• Medication Adherence in Youth With Sickle Cell Disease (SCD)CompletedNCT02143076
• Evaluation of Nocturnal Enuresis and Barriers to Treatment Among Pediatric Patients With Sickle Cell DiseaseCompletedNCT01959958
• Parent Willingness to Participate in Tobacco Trials in the Pediatric Clinical SettingCompletedNCT01673243
• The Feasibility of Text Messaging to Assess Secondhand Smoke Exposure Among Youngsters With Cancer or Sickle Cell DiseaseCompletedNCT01591187
• Adolescent, Caregiver, and Young Adult Perspectives of the Transition From Pediatric to Adult Care for Sickle Cell Disease: A Preliminary Evaluation of the Sickle Cell Disease Transition ProgramCompletedNCT01569971
• Genes Influencing Iron Overload StateCompletedNCT01158794
• State Of The Art Functional Imaging In Sickle Cell DiseaseCompletedNCT01137721
• The Brigance Assessment Of Individual Neurodevelopment In Young Children With Sickle Cell Disease- 2CompletedNCT01123863
• Long Term Effects of Erythrocyte LysisCompletedNCT00842621
• Bone Marrow for Hemoglobinopathy ResearchCompletedNCT00669305
• Long Term Effects of Hydroxyurea Therapy in Children With Sickle Cell DiseaseCompletedNCT00305175
• Stem Cell Transplantation With Identical Donors for Patients With Sickle Cell DiseaseCompletedNCT00186810Phase 2
• Haploidentical Stem Cell Transplant for Patients With Sickle Cell Disease and Prior Stroke or Abnormal Transcranial UltrasoundCompletedNCT00152113Phase 1
• Use of Hydroxyurea and Magnesium Pidolate for Treatment of Sickle Cell DiseaseCompletedNCT00143572Phase 1