Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: Leukemia trials

The registry lists 46 Leukemia studies with Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins as lead sponsor. 0 are open to participants now and 15 have results posted.

Phase 1 20Phase 2 24Phase 3 2No phase 3(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Study of Azacitidine in Combination With Pembrolizumab in R/R AML Patients and in Newly Diagnosed Older PatientsCompletedNCT02845297Phase 2Results posted
• Shorter Course Tacro After NMA, Related Donor PBSCT With High-dose Posttransplant Cy for Hard-to-Engraft MalignanciesCompletedNCT02556931Phase 2Results posted
• A Phase 1 Trial of TST of PD 0332991 Followed by Cytarabine and Mitoxantrone for Adults With Relapsed and Refractory Acute Leukemias and High-Risk MyelodysplasiaTerminatedNCT01701375Phase 1Results posted
• Phase II Study of Azacitidine and Sargramostim as Maintenance Treatment for Poor-Risk AML or MDSCompletedNCT01700673Phase 2Results posted
• Consolidation Therapy for Acute Myeloid Leukemia Guided by Leukemia Stem Cell BehaviorTerminatedNCT01588951Phase 2/3Results posted
• Reduced-intensity, Related-donor Bone Marrow Transplantation Followed by High-dose Cyclophosphamide for Hematologic CancersTerminatedNCT01135329Phase 2Results posted
• Allo BMT Using Matched Related/Unrelated Donors With FluBu and HiCYCompletedNCT00809276Phase 1/2Results posted
• Safety Study of Bone Marrow Transplant Using Mismatched Tissue Followed by ChemotherapyCompletedNCT00796562Phase 2Results posted
• Transplantation of Umbilical Cord Blood Following Chemotherapy for Blood CancersTerminatedNCT00539656Phase 1/2Results posted
• Bexarotene and GM-CSF in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid LeukemiaCompletedNCT00425477Phase 2Results posted
• Interferon and GM-CSF Compared With Imatinib Mesylate and Vaccine Therapy in Patients With Chronic Phase CML on a TKICompletedNCT00363649Phase 2Results posted
• Rituximab, Cyclophosphamide, and Pegfilgrastim in Treating Patients With Leukemia or Non-Hodgkin's LymphomaCompletedNCT00278161Phase 2Results posted
• Combination Chemotherapy, Bone Marrow Transplant, and Post Transplant Cyclophosphamide for Hematologic CancerCompletedNCT00134017Phase 2Results posted
• Fludarabine, Cyclophosphamide, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic CancerCompletedNCT00134004Phase 2Results posted
• Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed Burkitt's Lymphoma or LeukemiaCompletedNCT00133991Phase 2Results posted
• Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older PatientsActive, not recruitingNCT05823571Phase 1
• Resiliency in Older Adults Undergoing Bone Marrow TransplantCompletedNCT04188678
• Study of IRX5183 in Relapsed and Refractory Acute Myeloid Leukemia and High Risk Myelodysplastic SyndromeTerminatedNCT02749708Phase 1
• Red Cell Transfusion Goals in Patients With Acute LeukemiasCompletedNCT02086773Phase 1
• Endothelial Function, Arterial Stiffness and ComponentsCompletedNCT01439217
• Studying Fentanyl in Patients With CancerTerminatedNCT00899951
• Phase I Dose-Escalation Trial of Clofarabine Followed by Escalating Doses of Fractionated Cyclophosphamide in Children With Relapsed or Refractory Acute LeukemiasTerminatedNCT00852709Phase 1
• Vaccine Therapy With or Without Donor Lymphocyte Infusion in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Multiple Myeloma Undergoing Donor Stem Cell TransplantTerminatedNCT00469820Phase 1
• Cyclophosphamide Plus T-Cell Transplantation for Patients With Hematologic MalignanciesTerminatedNCT00356928Phase 1
• Cyclophosphamide and Rituximab Followed By Vaccine Therapy in Treating Patients With Chronic Lymphocytic LeukemiaWithdrawnNCT00343447Phase 2
• Clofarabine and Cyclophosphamide in Treating Patients With Relapsed or Refractory Acute Leukemia, Chronic Myelogenous Leukemia, or Myeloproliferative DisordersCompletedNCT00293410Phase 1
• Combination Chemotherapy in Treating Patients With Acute Promyelocytic LeukemiaCompletedNCT00276601Phase 2
• Rituximab and GM-CSF in Treating Patients With Chronic Lymphocytic LeukemiaTerminatedNCT00265915Phase 2
• Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic CancerCompletedNCT00265837Phase 3
• Cyclophosphamide and/or Mycophenolate Mofetil With or Without Tacrolimus in Treating Patients Who Are Undergoing a Donor Bone Marrow or Peripheral Stem Cell Transplant for Hematologic CancerCompletedNCT00255710Phase 1
• Ex Vivo Expansion of Mafosfamide Purged CD34+ Cells in Patients With Acute LeukemiaTerminatedNCT00245115Phase 1
• 3-AP Followed By Fludarabine In Treating Patients With Relapsed or Refractory Acute or Chronic Leukemia or High-Risk Myelodysplastic SyndromeCompletedNCT00077558Phase 1
• MS-275 in Treating Patients With Hematologic CancerCompletedNCT00015925Phase 1
• Bone Marrow Transplantation Plus Biological Therapy in Treating Patients With Chronic Myeloid LeukemiaCompletedNCT00011934Phase 2
• Phenylbutyrate and Tretinoin in Treating Patients With Hematologic CancerCompletedNCT00006239Phase 1
• Cyclophosphamide Plus Bone Marrow Transplantation in Treating Patients With Hematologic CancerCompletedNCT00006042Phase 1
• Azacitidine Plus Phenylbutyrate in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic SyndromeCompletedNCT00004871Phase 1
• Interleukin-2 Following Bone Marrow Transplantation in Treating Patients With Hematologic CancerCompletedNCT00003962Phase 1
• Sargramostim After Bone Marrow Transplantation in Treating Patients With Myelodysplastic SyndromeCompletedNCT00003961Phase 2
• Donor Bone Marrow Transplantation in Treating Patients With Hematologic CancerCompletedNCT00003960Phase 2
• Total-Body Irradiation, Tacrolimus, and Mycophenolate Mofetil Plus Bone Marrow Transplantation in Treating Patients With Hematologic CancersCompletedNCT00003572Phase 2
• Interferon Alfa Plus Sargramostim in Treating Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous LeukemiaTerminatedNCT00003561Phase 2
• Cyclophosphamide Plus Topotecan in Treating Patients With Refractory or Relapsed Acute Myelogenous LeukemiaCompletedNCT00003340Phase 2
• UCN-01 in Treating Patients With Advanced CancerCompletedNCT00003289Phase 1
• Combination Chemotherapy Plus Infusion of White Blood Cells in Treating Patients With Hematologic CancerCompletedNCT00003243Phase 1
• Sargramostim Following Allogeneic Bone Marrow Transplantation in Treating Patients With Chronic Myelogenous LeukemiaTerminatedNCT00002778Phase 2