Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: Carcinoma, Non-Small-Cell Lung trials

The registry lists 18 Carcinoma, Non-Small-Cell Lung studies with Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins as lead sponsor. 3 are open to participants now and 8 have results posted.

Early Phase 1 1Phase 1 4Phase 2 12No phase 2(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• DK222 Study at HopkinsRecruitingNCT07140315Phase 1
• Peptide Vaccine To Prevent Acquired Resistance In Patients With Advanced ALK+ NSCLCRecruitingNCT05950139Phase 1/2
• KRAS-Targeted Vaccine With Chemoimmunotherapy, Nivolumab and Ipilimumab for Patients With NSCLCRecruitingNCT05254184Phase 1
• Pathologic and Immunologic Response After Ablative Radiation in Lung CancerCompletedNCT03603002Not applicableResults posted
• Neoadjuvant Immunoradiation for Resectable Non-Small Cell Lung CancerTerminatedNCT03237377Phase 2Results posted
• Neoadjuvant Nivolumab, or Nivolumab in Combination With Ipilimumab, in Resectable NSCLCActive, not recruitingNCT02259621Phase 2Results posted
• Phase II Anti-PD1 Epigenetic Therapy Study in NSCLC.CompletedNCT01928576Phase 2Results posted
• A Randomized Phase II Study of SUBATM-itraconazole in Patients With Untreated Squamous NSCLC.TerminatedNCT01752023Phase 2Results posted
• Study of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Adenocarcinoma.TerminatedNCT01578551Phase 2Results posted
• Phase II Study of Itraconazole and Pemetrexed in Patients With Previously Treated Non-Squamous NSCLCTerminatedNCT00769600Phase 2Results posted
• Erlotinib, Paclitaxel, and Carboplatin in Treating Patients With Stage III, Stage IV, or Recurrent Non-Small Cell Lung CancerCompletedNCT00287989Phase 2Results posted
• PET Imaging With [18F]F-AraG in Advanced Non-small Cell Lung Cancer (NSCLC)TerminatedNCT04524195Phase 1
• Epidermal Growth Factor Receptor Mutations in the Blood of Patients With Advanced Non-Small Cell Lung CancerCompletedNCT00899756
• Laboratory Test in Predicting Response to Erlotinib in Patients With Relapsed Metastatic or Unresectable Non-Small Cell Lung Cancer That Did Not Respond to Previous TreatmentCompletedNCT00673569Phase 2
• Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial CancerTerminatedNCT00499733Early Phase 1
• Lomustine in Treating Patients With Stage III or Stage IV Non-Small Cell Lung CancerCompletedNCT00293280Phase 2
• Docetaxel and Cisplatin in Treating Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer That Has Been Completely Removed By SurgeryCompletedNCT00281970Phase 2
• Gemcitabine and Carboplatin Followed by Paclitaxel in Treating Patients With Stage III or Stage IV Non-Small Cell Lung CancerCompletedNCT00276588Phase 2