Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: Astrocytoma trials

The registry lists 10 Astrocytoma studies with Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins as lead sponsor. 0 are open to participants now and 1 have results posted.

Early Phase 1 1Phase 1 5Phase 2 4No phase 2(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGGTerminatedNCT03973918Phase 2Results posted
• Determining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients With High Grade GliomasTerminatedNCT03971734Phase 1
• A Biospecimen Collection Study in BRAF-V600E Mutated Recurrent GliomasTerminatedNCT03593993
• Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain TumorsCompletedNCT02644291Phase 1
• A Safety Study of Fingolimod With Radiation and Temozolomide in Newly Diagnosed High Grade GliomaCompletedNCT02490930Early Phase 1
• Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant AstrocytomasTerminatedNCT01502605Phase 1
• Study of Blood Samples and Risk of Infection in Patients With Newly Diagnosed Malignant Supratentorial AstrocytomaCompletedNCT00999622
• Gefitinib in Treating Patients With Recurrent or Progressive CNS TumorsCompletedNCT00025675Phase 2
• Imatinib Mesylate in Treating Patients With Recurrent Malignant Glioma or MeningiomaCompletedNCT00010049Phase 1/2
• SU5416 in Treating Patients With Recurrent Astrocytoma or Mixed Glioma That Has Not Responded to Radiation TherapyCompletedNCT00004868Phase 1/2