Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: Adenocarcinoma trials

The registry lists 23 Adenocarcinoma studies with Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins as lead sponsor. 4 are open to participants now and 17 have results posted.

Early Phase 1 1Phase 1 4Phase 2 15Phase 3 1No phase 4(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal CancerRecruitingNCT07281768Phase 2
• Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic CancerRecruitingNCT06782932Phase 1/2
• Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients With Metastatic Prostate CancerRecruitingNCT06616597Phase 2
• Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal CancerRecruitingNCT06205836Phase 2
• Study of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic CancerCompletedNCT05014776Phase 2Results posted
• Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal CancerCompletedNCT03642067Phase 2Results posted
• Muscadine Plus (MPX) In Men With Prostate CancerTerminatedNCT03535675Phase 3Results posted
• Radiopaque Hydrogel in Patients Undergoing Radiotherapy for Pancreatic CancerCompletedNCT03307564Not applicableResults posted
• A Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable or Metastatic Cholangiocarcinoma and Pancreatic AdenocarcinomaCompletedNCT03250273Phase 2Results posted
• Pilot Study With CY, Pembrolizumab, GVAX, and IMC-CS4 (LY3022855) in Patients With Borderline Resectable Adenocarcinoma of the PancreasCompletedNCT03153410Early Phase 1Results posted
• Pilot Study of 18F-DCFPyL PET/CT in the Evaluation of Men With an Elevated PSA Following Radical ProstatectomyCompletedNCT02523924Not applicableResults posted
• GVAX Pancreas Vaccine (With CY) and CRS-207 With or Without NivolumabCompletedNCT02243371Phase 2Results posted
• Intraoperative Dosimetry for Prostate Brachytherapy Using Fluoroscopy and UltrasoundCompletedNCT02225925Not applicableResults posted
• Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Metastatic Colorectal AdenocarcinomaTerminatedNCT01639131Phase 2Results posted
• Pancreatic Tumor Cell Vaccine (GVAX), Cyclophosphamide, SBRT, and FOLFIRINOX in Patients With Resected Adenocarcinoma of the PancreasCompletedNCT01595321Phase 2Results posted
• Study of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Adenocarcinoma.TerminatedNCT01578551Phase 2Results posted
• Gemcitabine + Nab-paclitaxel With LDE-225 (Hedgehog Inhibitor) as Neoadjuvant Therapy for Pancreatic AdenocarcinomaTerminatedNCT01431794Phase 1/2Results posted
• Hedgehog Inhibitors for Metastatic Adenocarcinoma of the PancreasCompletedNCT01088815Phase 2Results posted
• Boost GVAX Pancreas Vaccine With or Without CY in Patients With Pancreas CancerActive, not recruitingNCT01088789Phase 2Results posted
• Spect Analysis of Cardiac Perfusion Changes After Whole Breast/Chest Wall Radiation Therapy With ABCCompletedNCT00321048Not applicableResults posted
• Vaccine Therapy Combined With Adjuvant Chemoradiotherapy in Treating Patients With Resected Stage I or Stage II Adenocarcinoma (Cancer) of the PancreasCompletedNCT00084383Phase 2Results posted
• A Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic CancerCompletedNCT02048384Phase 1
• Study of Image-guided Dosimetry for Interstitial Prostate BrachytherapyCompletedNCT00426959Phase 1