Second Affiliated Hospital, School of Medicine, Zhejiang University: Colorectal Neoplasms trials

The registry lists 30 Colorectal Neoplasms studies with Second Affiliated Hospital, School of Medicine, Zhejiang University as lead sponsor. 17 are open to participants now and 0 have results posted.

Phase 1 6Phase 2 13Phase 3 4No phase 10(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Colorectal Adenoma CohortNot yet recruitingNCT07523035
• Everolimus in CDK12-Deficient Metastatic Colorectal Cancer (EVER-RECODE)Not yet recruitingNCT07435584Phase 1/2
• Neoadjuvant Chemotherapy, Anti-PD-1 Antibody and Sitagliptin for Locally Advanced pMMR CRCRecruitingNCT07365592Phase 1/2
• A Prospective, Safety, and Efficacy Clinical Trial of Pressurized Intraperitoneal Aerosol Therapy for Peritoneal Metastasis of Colorectal CancerRecruitingNCT07349043Phase 1
• Efficacy and Safety of AK104 Combined With Chemotherapy and Cetuximab or BevacizumabRecruitingNCT07253896Phase 2
• Trifluridine/Tipiracil Plus Regorafenib vs Trifluridine/Tipiracil Plus Bevacizumab for Refractory Metastatic Colorectal CancerRecruitingNCT06992648Phase 3
• Exploratory Clinical Study of Claudin18.2-Targeted CAR-DC and CAR-T Therapy in Advanced Colorectal CancerRecruitingNCT06946615Phase 1
• Efficacy and Safety of Trifluridine/Tipiracil (TAS-102) Combined With Bevacizumab and Serplulimab in Patients With Metastatic Colorectal Cancer Undergoing Cytoreductive Surgery: A Single-Arm, Single-Center Clinical StudyNot yet recruitingNCT06882915Phase 1
• The Study on the Efficacy and Safety of Lactobacillus Johnsonii in Combination with CapeOX and Pembrolizumab for the Treatment of MSS/pMMR Metastatic Colorectal Cancer.Not yet recruitingNCT06823323Not applicable
• Raman Spectroscopy-Based Deep Learning Model for Early Pan-Cancer Early DiagnosisRecruitingNCT06822413
• A Real-world Study of Trifluridine/Tipiracil Containing Regimen for the Treatment of Patients With mCRC (REFLECT Study)Not yet recruitingNCT06195111
• Bemalenograstim Alfa for the Prevention in Patients With Colorectal Cancer/Pancreatic CancerNot yet recruitingNCT06134765Phase 2
• Serplulimab+Regorafenib +Hepatic Artery Bicarbonate Infusion in Patients With Colorectal Cancer and Liver MetastasesNot yet recruitingNCT05894837Phase 2
• Explore Biomarkers Associated With Prognosis of Recurrent and Metastatic CRC After Surgery by Multi-omics MethodsRecruitingNCT05501353
• SALIRI Based Regimen as First-line Treatment for Advanced Metastatic Colorectal CancerRecruitingNCT05160896Phase 2
• Study of the Safety and Effectiveness of HIFU Combined With REGOTORI for Metastatic Colorectal CancerRecruitingNCT04819516Phase 1
• Probiotics Combined With Standard Chemotherapy Plus Targeted Therapy in Patients With Metastatic Colorectal CancerNot yet recruitingNCT04131803Not applicable
• Exploratory Study of a Novel Based rbcDNA Liquid Biopsy Technique for Colorectal Cancer Early DetectionCompletedNCT05875584
• RC48-ADC Combined With Bevacizumab in HER2-positive Advanced Colorectal CancerStatus unknownNCT05785325Phase 2
• Hyperthermic Intraperitoneal Treatment of rmhTNF for CRCPM: Phase II Clinical TrialStatus unknownNCT05755685Phase 2
• Exploratory Study on Combined Conversion Immunotherapy for Liver Metastasis of MSS Type Initial Unresectable Colorectal Cancer Based on Gene StatusStatus unknownNCT05409417Phase 2/3
• mFOLXOX6 Versus FOLFIRI for Colorectal Patients Recurrence After Oxaplatin Based Adjuvant ChemotherapyStatus unknownNCT05362617Phase 3
• Combination With Sintilimab and XELOX+Bevacizumab as 1st Line Therapy in RAS-mutant Metastatic Colorectal CancerActive, not recruitingNCT05171660Phase 3
• Multicenter Study on the Pathogenic Germline Gene Variants of Colorectal Polyposis in ChinaStatus unknownNCT04961125
• Multi-center Application of Quantitative FIT Technology in Colorectal Cancer ScreeningStatus unknownNCT04959617
• Establishment and Clinical Validation of New Technologies for Accurate Screening of Colorectal Cancer Based on Multi-omicsStatus unknownNCT04913233
• Fruquintinib Plus Capecitabine Versus Bevacizumab Plus Capecitabine as Maintenance Therapy Following First-line Treatment for Metastatic Colorectal CancerStatus unknownNCT04733963Phase 2
• QL1101 in Combination With JS001 in Patients With pMMR/MSS Refractory Metastatic Colorectal CancerStatus unknownNCT04527068Phase 2
• A Clinical Study of Pyrotinib in Patients With HER2-positive Advanced Colorectal CancerStatus unknownNCT04380012Phase 2
• Sintilimab (IBI308) Combined With Bevacizumab + XELOX Regimen in Metastatic Colorectal CancerStatus unknownNCT04194359Phase 2