Radboud University Medical Center: Malaria trials

The registry lists 24 Malaria studies with Radboud University Medical Center as lead sponsor. 0 are open to participants now and 5 have results posted.

Phase 1 6Phase 2 5Phase 4 1No phase 16(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Safety and Efficacy of R0.6C VaccineCompletedNCT04862416Phase 1Results posted
• Safety, Tolerability, and Pharmacokinetics and Pharmacodynamics of TB31FCompletedNCT04238689Phase 1Results posted
• Safety and Efficacy of NF135 CPS ImmunizationTerminatedNCT03813108Not applicableResults posted
• Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2CompletedNCT03454048Not applicableResults posted
• Safety and Protective Efficacy of Pb(PfCS@UIS4)CompletedNCT03138096Phase 1/2Results posted
• Controlled Human Malaria Infection Model for Evaluation of Transmission-Blocking Interventions - Study 1CompletedNCT02836002Phase 1/2
• Safety and Protective Efficacy of BCG Vaccination Against Controlled Human Malaria InfectionCompletedNCT02692963Phase 2
• Controlled Human Malaria Infection After Bites From Mosquitoes Infected With Two Novel P. Falciparum StrainsCompletedNCT02149550Not applicable
• Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous InfectionCompletedNCT02098590Not applicable
• Target Antigens Induced by Plasmodium Falciparum Sporozoite Immunization Under ChemoprophylaxisCompletedNCT02080026Not applicable
• Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine or Chloroquine/Azithromycin ProphylaxisWithdrawnNCT01783340Phase 1/2
• Re-exposure of Human Volunteers to a Heterologous Strain of P. Falciparum SporozoitesCompletedNCT01660854Not applicable
• Comparison of Three Plasmodium Falciparum Isolates in a Controlled Human Malaria InfectionCompletedNCT01627951Not applicable
• Reducing the Burden of Malaria by Targeting Hotspots of Malaria TransmissionCompletedNCT01575613Not applicable
• Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Versus Mefloquine ProphylaxisCompletedNCT01422954Not applicable
• Experimental Human Malaria Infection After Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine ProphylaxisCompletedNCT01236612Not applicable
• Immunization With Different Doses of Plasmodium Falciparum Sporozoites Under Chloroquine ProphylaxisCompletedNCT01218893Not applicable
• Correlating Protection Against Malaria With Serum Profiles Against Plasmodium Falciparum Antigen RepertoiresCompletedNCT01214876
• Comparison of Three Plasmodium Falciparum Isolates in an Experimental Human Malaria InfectionCompletedNCT01002833Not applicable
• Treatment Efficacy and Malaria TRANSmission After Artemisinin Combination Therapy (TRANSACT)CompletedNCT00868465Not applicable
• Re-exposure of EHMI-8 Human Volunteers to Live Malaria SporozoitesCompletedNCT00757887Not applicable
• Safety and Efficacy Study of Plasmodium Falciparum LSA-3 Malaria VaccineCompletedNCT00509158Phase 1/2
• Study to Investigate the Induction of an Protective Immune Response to MalariaCompletedNCT00442377Not applicable
• Drug Interaction Study Between Atovaquone and Antiretroviral Agents in HIV-1 Infected PatientsCompletedNCT00421473Phase 4