Pfizer: Migraine Disorders trials

The registry lists 47 Migraine Disorders studies with Pfizer as lead sponsor. 10 are open to participants now and 24 have results posted.

Phase 1 7Phase 2 6Phase 3 23Phase 4 6No phase 10(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study to Learn About the Study Medicine Called Rimegepant in Adults When Used for the Prevention of Chronic MigraineRecruitingNCT07729462Phase 3
• A Study to Find Out if the Medicine Called Rimegepant is Safe for Adults in IndiaRecruitingNCT07685769Phase 4
• A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With MigraineRecruitingNCT07609914Phase 4
• A Study to Learn About the Study Medicine NURTEC® ODT 75 mg After it is Released Into the Markets in KoreaNot yet recruitingNCT07497854
• A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of MigraineRecruitingNCT06995729Phase 1
• A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual MigraineRecruitingNCT06641466Phase 3
• Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric SubjectsRecruitingNCT05156398Phase 3
• Observational Study to Assess Maternal, Fetal and Infant Outcomes Following Exposure to RimegepantRecruitingNCT05046613
• Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of MigraineRecruitingNCT04743141Phase 3
• Randomized Study in Children and Adolescents With Migraine: Acute TreatmentRecruitingNCT04649242Phase 3
• Comparison of Patient-reported Outcomes for Rimegepant and Triptans in the 2023 US National Health and Wellness SurveyCompletedNCT06680206Results posted
• A Study to Learn About the Benefit of Rimegepant Versus Triptans in Migraine Buddy App Users.CompletedNCT06532357Results posted
• Reliability of Rimegepant or Triptans for the Acute Treatment of MigraineCompletedNCT06412965Results posted
• A Study to Learn About Zavegepant as the Acute Treatment of Migraine in Asian AdultsCompletedNCT05989048Phase 3Results posted
• A Study to Compare Zavegepant Concentration Using Samples Collected From the Vein Versus Patient-Centric MicrosamplingCompletedNCT05948085Phase 1Results posted
• A Study to Learn About the Safety and Effects of Rimegepant to Prevent Migraine in Chinese Subjects.CompletedNCT05810038Phase 3Results posted
• Efficacy and Tolerability of Rimegepant for the Prevention of Migraine in Adults With History of Inadequate Response to Oral Preventive MedicationsCompletedNCT05518123Phase 4Results posted
• Efficacy and Tolerability of Rimegepant for the Acute Treatment of Migraine in Adults Unsuitable for Triptan UseCompletedNCT05509400Phase 4Results posted
• Efficacy and Safety Study of Rimegepant for Migraine Prevention in Japanese Subjects (Japan Only)CompletedNCT05399485Phase 3Results posted
• Efficacy and Safety Study of Rimegepant for the Acute Treatment of Migraine in Japanese Subjects (Japan Only)CompletedNCT05399459Phase 3Results posted
• A Study to Learn About the Long-term Safety of Rimegepant for the Acute Treatment of Migraine in Chinese ParticipantsCompletedNCT05371652Phase 3Results posted
• Efficacy and Safety Study of Rimegepant in Episodic Migraine Prevention With Multiple Dosing RegimensCompletedNCT05217927Phase 4Results posted
• Safety and Tolerability Study of Daily Dosing Rimegepant in Episodic Migraine PreventionCompletedNCT05207865Phase 4Results posted
• A Study to Evaluate the Efficacy and Safety of Oral Zavegepant in Migraine PreventionTerminatedNCT04804033Phase 2/3Results posted
• Safety and Efficacy Trial of BHV3000 (Rimegepant) 75 mg for the Acute Treatment of MigraineCompletedNCT04574362Phase 3Results posted
• Randomized Trial in Adult Participants With Acute MigrainesCompletedNCT04571060Phase 3Results posted
• Long-term Safety Study of BHV-3500 (Zavegepant*) for the Acute Treatment of MigraineCompletedNCT04408794Phase 2/3Results posted
• Acute Treatment Trial in Adult Subjects With MigrainesCompletedNCT03872453Phase 2/3Results posted
• Efficacy and Safety Trial of Rimegepant for Migraine Prevention in AdultsCompletedNCT03732638Phase 2/3Results posted
• Trial in Adult Subjects With Acute MigrainesCompletedNCT03461757Phase 3Results posted
• Open Label Safety Study in Acute Treatment of MigraineCompletedNCT03266588Phase 2/3Results posted
• Safety and Efficacy in Adult Subjects With Acute MigrainesCompletedNCT03237845Phase 3Results posted
• Safety and Efficacy Study in Adult Subjects With Acute MigrainesCompletedNCT03235479Phase 3Results posted
• Dose Ranging Study of Rimegepant (BMS-927711) for the Acute Treatment of MigraineCompletedNCT01430442Phase 2Results posted
• Efficacy of Rimegepant 75 mg for the Acute Treatment of Migraine: a Bayesian Individual Participant Data Meta-analysis Standardized to Defined Target PopulationsActive, not recruitingNCT07906262
• A Study to Compare the Blood Levels of Two Dosage Formulations of the Study Medicine in Healthy AdultsCompletedNCT07594769Phase 1
• Consistency of Response With Rimegepant in Acute Treatment of MigraineActive, not recruitingNCT06898047
• A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent MigraineActive, not recruitingNCT06616194Phase 3
• A Real-world, Prospective Observational Study of Rimegepant ODT for the Acute Treatment of Migraine Attacks in Adults.CompletedNCT06467370
• A Study to Learn About Zavegepant as a Treatment for Multiple Migraine Attacks in Adult ParticipantsWithdrawnNCT06103734Phase 3
• Study of Pregnancy Outcomes in Women Exposed to Rimegepant During PregnancyActive, not recruitingNCT05198245
• An Open-label, Intermediate Size, Expanded Access Study of BHV-3000 in the Acute Treatment of MigraineNo longer availableNCT03934086
• A Study of the Safety, Tolerability, Pharmacokinetics, And Effects On Histamine-Induced Wheal Of PF-05180999 In Healthy AdultsTerminatedNCT01981499Phase 1
• A Study Of The Safety, Tolerability, And Pharmacokinetics Of Multiple Doses Of PF-05180999 In Healthy AdultsWithdrawnNCT01981486Phase 1
• Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study Of PF-04427429 In Healthy Women VolunteersCompletedNCT01511497Phase 1
• Study to Evaluate the PK of BMS-927711 in Patient With Migraine During Acute Migraine and Non-migraine ConditionCompletedNCT01445067Phase 1
• A Study to Assess an Auto-injector Being Used to Treat a Migraine AttackCompletedNCT00510419Phase 3