Otsuka Pharmaceutical Co., Ltd. clinical trials

A subsidiary of Otsuka Holdings Co., Ltd.

The registry lists 143 studies whose lead sponsor is Otsuka Pharmaceutical Co., Ltd.. 11 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 23, 2026.

Studies

Recruiting first, then most recently updated. Showing 50 of 143. List all 143 → · All Otsuka Holdings Co., Ltd. studies →

• A Long-term Trial of EB-1020 in Adult Patients With ADHDRecruitingNCT06926829Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Evaluation of the Efficacy and Safety of EB-1020 in Adult ADHD PatientsRecruitingNCT06931080Phase 2/3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• REXULTI General Use Results Survey in Patients With Hyperactivity, or Aggressive Behavior Associated With Alzheimer's DementiaRecruitingNCT06875986

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• LUPKYNIS Drug-use Results SurveyRecruitingNCT07053891

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Trial of Brexpiprazole Once-weekly (QW) Formulation in Patients With Acute SchizophreniaRecruitingNCT05325645Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Specified Drug Use Survey on AJOVY Subcutaneous Injection for Long-term UseRecruitingNCT05342493

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Long-term Administration Trial of SEP-363856 in Patients With SchizophreniaRecruitingNCT07225712Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Long-term Trial of EB-1020 in Pediatric Patients With ADHDRecruitingNCT07087327Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Trial to Evaluate the Efficacy and Safety of EB-1020 in Pediatric Patients With ADHDRecruitingNCT07086313Phase 2/3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Phase 3 Trial of OPA-15406 Foam in Children and Infants With Atopic DermatitisNot yet recruitingNCT07184645Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Phase 3 Trial to Demonstrate the Superiority of 1% OPA-15406 Foam to the Vehicle in Adult Patients With Atopic DermatitisNot yet recruitingNCT07173478Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Safety and Efficacy Study of OPC-415 in Patients With Relapsed and/or Refractory Multiple MyelomaTerminatedNCT04649073Phase 1/2

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Long-term Administration Trial of Brexpiprazole Once-weekly (QW) Formulation in Patients With SchizophreniaCompletedNCT05326347Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Samtasu Post-marketing General Drug Use-results Survey in Patients With Volume Overload in Heart Failure.Active, not recruitingNCT05712746

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Samsca Post-marketing General Drug Use-results Survey in Patients With Hyponatremia in SIADHActive, not recruitingNCT04790175

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Phase 1 Trial of OPB-111077 in Combination With Bendamustine and Rituximab in Patients With r/r DLBCLCompletedNCT04049825Phase 1

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Phase I/II Study of ASTX660 in Patients With Relapsed or Refractory T-cell LymphomaTerminatedNCT04362007Phase 1/2

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Long-term Trial of ETC-1002 in Patients With Hyper-LDL CholesterolemiaCompletedNCT05687071Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Food Effect Study of Brexpiprazole Once-weekly (QW) Formulation in Patients With SchizophreniaCompletedNCT06036108Phase 1

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Post-Marketing Surveillance Study of Tolvaptan in Patients With ADPKDCompletedNCT02847624

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Dose-ranging Trial of OPC-131461 in Cardiac Edema (Congestive Heart Failure [CHF])CompletedNCT05615363Phase 2

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Long-term Trial of OPA-15406 in Infants With Atopic DermatitisCompletedNCT05372653Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Specified Drug-use Survey on Abilify Prolonged Release Aqueous Suspension for IM Injection (Prevention of Relapse of Mood Episodes in BP)CompletedNCT04812379

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Post-Marketing Surveillance Study of Nalmefene Hydrochloride Hydrate in Patients with Alcohol DependenceCompletedNCT04107051

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Phase 1 Trial of ASTX727 in Subjects With Lower-risk Myelodysplastic SyndromesActive, not recruitingNCT03906695Phase 1

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Confirmatory Trial of ETC-1002 in Patients With Hyper-LDL CholesterolemiaCompletedNCT05683340Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Brexpiprazole for the Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's TypeCompletedNCT03620981Phase 2/3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Brexpiprazole for the Long-term Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's TypeCompletedNCT03724942Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Phase 2 Trial of OPC-64005 for Major Depressive DisorderCompletedNCT04244253Phase 2

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics Study of Tolvaptan in Pediatric Congestive Heart Failure (CHF) Patients With Volume OverloadCompletedNCT03255226Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Study of Brexpiprazole in Patients With Major Depressive DisorderCompletedNCT03697603Phase 2/3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Long-term, Extended Treatment Study of Aripiprazole in Pediatric Patients With Autistic DisorderCompletedNCT01617460Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Clinical Pharmacology Trial of Brexpiprazole Once-weekly (QW) Formulation Administered as Single and Multiple Oral DosesCompletedNCT04118127Phase 1

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Dose-finding Trial of ETC-1002(Bempedoic Acid) in Patients With HypercholesterolemiaCompletedNCT04784442Phase 2

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Long-Term Study of Brexpiprazole in Patients With Major Depressive DisorderCompletedNCT03737474Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Long-term Safety and Tolerability of Subcutaneous Administration of TEV-48125 for the Preventive Treatment of MigraineCompletedNCT03303105Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Clinical Pharmacology Trial of Brexpiprazole Long Acting Injectable (LAI) Administered as a Single Dose in Patients With SchizophreniaWithdrawnNCT05119894Phase 1

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Long-term Trial of OPA-15406 Ointment in Adult and Pediatric Patients With Atopic DermatitisCompletedNCT03961529Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Safety Evaluation Trial of TEV-48125 Self-administered in Migraine PatientsCompletedNCT04355117Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Phase 2 Trial of Rebamipide Liquid to Determine the Effective Dose for Prevention of Chemoradiotherapy-induced Oral Mucositis in Patients With Head and Neck CancerCompletedNCT02085460Phase 2

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Pharmacodynamic Study of Cilostazol in Healthy VolunteersCompletedNCT02554721Phase 1

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• A Phase I, Open-Label Trial to Assess the Absorption, Metabolism, and Excretion of (14C)-OPC-61815 in Healthy Male Japanese SubjectsCompletedNCT04182958Phase 1

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Post-Marketing Surveillance Study of Aripiprazole in Patients With AutismCompletedNCT03179787

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Safety Trial of OPC-61815 Injection in Patients With Congestive Heart Failure Who Have Difficulty With or Are Incapable of Oral IntakeCompletedNCT03962101Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Efficacy and Safety Trial of OPC-61815 Injection Compared With Tolvaptan 15-mg Tablet in Patients With Congestive Heart FailureCompletedNCT03772041Phase 3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Efficacy and Safety of Subcutaneous Administration of TEV-48125 for the Preventive Treatment of Episodic MigraineCompletedNCT03303092Phase 2/3

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Clinical Pharmacology Trial to Investigate the Dose of OPC-61815 Injection Equivalent to Tolvaptan 15-mg Tablet in Patients With Congestive Heart FailureCompletedNCT03254108Not applicable

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Bioequivalence Study of Brexpiprazole Orally Disintegrating Tablets (ODT) 2mgCompletedNCT03902574Phase 1

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• An Exploratory Study of Rebamipide in Patients With Active Ulcerative ColitisCompletedNCT00463151Phase 2

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.

• Safety Study of OPC-12759 Ophthalmic SolutionCompletedNCT01471093Phase 1

  Sponsor listed in the registry: Otsuka Pharmaceutical Co., Ltd.