Otsuka Holdings Co., Ltd.: Inappropriate ADH Syndrome trials

The registry lists 10 Inappropriate ADH Syndrome studies with Otsuka Holdings Co., Ltd. as lead sponsor. 0 are open to participants now and 5 have results posted.

Phase 1 1Phase 2 1Phase 3 4No phase 5(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Multicenter Trial to Investigate the Efficacy and Safety of Tolvaptan in Patients With Hyponatremia in SIADHCompletedNCT03048747Phase 3Results posted
• An Observational Study to Describe the Adherence to the SEOM Algorithm for the Treatment of Hyponatraemia in SpainCompletedNCT02548845Results posted
• An Observational Study on Real-world Use and Outcomes of Patients Treated With Tolvaptan for Hyponatraemia Due to SIADHCompletedNCT02545101Results posted
• A PK Study of 3 Dosages of Tolvaptan in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)CompletedNCT02009878Phase 1/2Results posted
• Effects of Tolvaptan vs Fluid Restriction in Hospitalized Subjects With Dilutional HyponatremiaTerminatedNCT01227512Phase 3Results posted
• Samsca Post-marketing General Drug Use-results Survey in Patients With Hyponatremia in SIADHActive, not recruitingNCT04790175
• An Observational Study Measuring Outcomes in Cancer Patients Treated for Moderate to Severe Hyponatremia in ItalyCompletedNCT02573077
• Post-Authorisation Safety Study of Samsca (Tolvaptan) Used in Routine Medical PracticeStatus unknownNCT01228682
• Study of Ascending Levels of Tolvaptan in HyponatremiaCompletedNCT00201994Phase 3
• "SALT Trial" Study of Ascending Levels of Tolvaptan in HyponatremiaCompletedNCT00072683Phase 3