Otsuka Holdings Co., Ltd.: Bipolar Disorder trials

The registry lists 28 Bipolar Disorder studies with Otsuka Holdings Co., Ltd. as lead sponsor. 1 are open to participants now and 12 have results posted.

Phase 1 3Phase 3 18Phase 4 5No phase 2(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study of Abilify® Tablet(Aripiprazole) as an Adjunctive Treatment in the Bipolar DepressionRecruitingNCT03423680Phase 3
• A Trial to Assess Brexpiprazole Versus Placebo for the Treatment of Acute Manic Episodes Associated With Bipolar I DisorderCompletedNCT03259555Phase 3Results posted
• A Trial to Assess Brexpiprazole Versus Placebo for the Treatment of Acute Manic Episodes, Associated With Bipolar I DisorderCompletedNCT03257865Phase 3Results posted
• Safety and Tolerability of Aripiprazole in Adolescents With Schizophrenia or Children and Adolescents With Bipolar I Disorder, Manic or Mixed Episode With or Without Psychotic Features.TerminatedNCT01122927Phase 3Results posted
• Study to Evaluate the Efficacy and Safety of Aripiprazole Administered With Lithium or Valproate Over 12 Weeks in the Treatment of Mania in Bipolar I DisorderCompletedNCT00665366Phase 3Results posted
• A Multicenter, Investigative Study of the Safety and Efficacy of Extended Administration of Aripiprazole in Combination With Mood Stabilizer for the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed EpisodeCompletedNCT00606320Phase 3Results posted
• A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group-comparison Trial of Aripiprazole in the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed EpisodeCompletedNCT00606281Phase 3Results posted
• A Multicenter Investigative Study of the Safety and Efficacy of Long-term Administration of Aripiprazole in Combination With Mood Stabilizer for the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed EpisodeCompletedNCT00606229Phase 3Results posted
• A Multicenter, Placebo-controlled, Double-blind Investigative Extension Trial of the Safety and Efficacy of Aripiprazole in the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed EpisodeCompletedNCT00606177Phase 3Results posted
• A Phase IV Study of the Safety and Efficacy of Aripiprazole in Combination With Lamotrigine in the Long-Term Maintenance Treatment of Patients With Bipolar I Disorder With A Recent Manic or Mixed EpisodeCompletedNCT00277212Phase 4Results posted
• A Study of Aripiprazole (Abilify) in Patients With Bipolar ManiaCompletedNCT00261443Phase 4Results posted
• Aripiprazole in Children and Adolescents With Bipolar I DisorderCompletedNCT00110461Phase 3Results posted
• Aripiprazole Open-Label, Safety and Tolerability StudyCompletedNCT00102518Phase 3Results posted
• A Study of SEP-380135 in Adults With Schizophrenia or Major Depressive EpisodeCompletedNCT07549581Phase 1
• Specified Drug-use Survey on Abilify Prolonged Release Aqueous Suspension for IM Injection (Prevention of Relapse of Mood Episodes in BP)CompletedNCT04812379
• Trial to Assess the Bioavailability of Quetiapine Versus Seroquel® in Subjects With Schizophrenia or Bipolar DisorderCompletedNCT03872596Phase 1
• Abilify in Bipolar Disorder for 24 Weeks Treatment EffectivenessCompletedNCT00545675Phase 4
• Abilify in Bipolar Disorder for 6 Weeks Treatment EffectivenessCompletedNCT00545142Phase 4
• ABLE: Abilify in Bipolar Disorder for Long-term EffectivenessCompletedNCT00484471Phase 4
• A Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depressive EpisodeWithdrawnNCT00338273Phase 3
• Drug-drug Interaction Study of Aripiprazole and Lamotrigine in Patients With Bipolar Type I DisorderCompletedNCT00321516Phase 1
• Study of Aripiprazole in Patients With Bipolar I DisorderCompletedNCT00257972Phase 3
• Efficacy and Safety of Aripiprazole in Patients With Schizophrenia or Bipolar DisorderCompletedNCT00216723
• Study of Aripiprazole in Patients With Acute Bipolar ManiaCompletedNCT00097266Phase 3
• Aripiprazole in Patients With Acute ManiaCompletedNCT00095511Phase 3
• Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depression EpisodeCompletedNCT00080314Phase 3
• Study of Aripiprazole in Patients With a History of Bipolar DisorderCompletedNCT00036348Phase 3
• Study of Aripiprazole in the Treatment of Patients With Acute Symptoms in Bipolar DisorderCompletedNCT00036101Phase 3