Novo Nordisk A/S: Heart Failure trials

The registry lists 14 Heart Failure studies with Novo Nordisk A/S as lead sponsor. 5 are open to participants now and 1 have results posted.

Phase 1 4Phase 2 4Phase 3 3No phase 3(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study Understanding How Much CDR132L Enters the Bloodstream After Injection Under the Skin Compared to Injection Into a Vein in Healthy ParticipantsRecruitingNCT07656454Phase 1
• A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and ObesityRecruitingNCT07567001Phase 3
• A Research Study on the Effects of NNC0537-1482 in Participants With Heart FailureRecruitingNCT07218627Phase 1
• A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular HypertrophyRecruitingNCT06979375Phase 2
• A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular HypertrophyRecruitingNCT06979362Phase 2
• Study to Assess Efficacy and Safety of CDR132L in Patients With Reduced Left Ventricular Ejection Fraction After Myocardial InfarctionCompletedNCT05350969Phase 2Results posted
• Focus on Levels of Awareness and Perceptions Regarding hsCRP in Identifying Systemic Inflammation in ASCVD, CKD and Heart Failure ManagementCompletedNCT07160829
• A Master Protocol for Semaglutide Effects on Cardiovascular and Obesity-related Outcomes in People With Overweight or Obesity in the Real WorldCompletedNCT07141914
• A Research Study on the Effects of NNC0537-1482 in Healthy Individuals When Injected Under the SkinCompletedNCT06625307Phase 1
• A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and InflammationActive, not recruitingNCT06200207Phase 3
• Levels of Inflammation in People With Cardiovascular Disease (POSEIDON)CompletedNCT06122961
• Reverse Remodeling Effects of CDR132L in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction and Cardiac HypertrophyWithdrawnNCT05953831Phase 2
• A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and InflammationTerminatedNCT05636176Phase 3
• Clinical Study to Assess Safety, PK and PD Parameters of CDR132LCompletedNCT04045405Phase 1