Novartis: Dyslipidemias trials

The registry lists 27 Dyslipidemias studies with Novartis as lead sponsor. 5 are open to participants now and 4 have results posted.

Phase 1 2Phase 2 2Phase 3 8Phase 4 10No phase 5(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Real World Adherence of PCSK9 Targeted TherapyNot yet recruitingNCT07468500
• Study to Evaluate the Impact of a Targeted Lipid Optimization Program on LDL-C Control in At-risk Adult Patients With DyslipidemiaRecruitingNCT07034690Phase 4
• Leqvio rPMS (Regulatory Post-Marketing Surveillance in Korea)RecruitingNCT06770543
• Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial HypercholesterolemiaRecruitingNCT06597019Phase 3
• Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial HypercholesterolemiaRecruitingNCT06597006Phase 3
• Study of Efficacy, Safety, Tolerability and Quality of Life of Inclisiran (KJX839) vs Placebo, on Top of Ongoing Individually Optimized Lipid-lowering Therapy, in Participants With HypercholesterolemiaCompletedNCT05192941Phase 4Results posted
• Study of Efficacy and Safety of Inclisiran in Japanese Participants With High Cardiovascular Risk and Elevated LDL-CCompletedNCT04666298Phase 2Results posted
• Efficacy and Safety of Fluvastatin Sodium Extended Release Tablets 80 mg Once Daily in Chinese Patients With Primary Hypercholesterolemia or Mixed DyslipidemiaCompletedNCT01551173Phase 4Results posted
• Effects of Nateglinide vs Acarbose on Postprandial Glucose Fluctuation, Dyslipidemia, and Inflammatory FactorsCompletedNCT00928889Phase 4Results posted
• A Study of DII235 in Adults With Elevated Lipoprotein(a)Active, not recruitingNCT07235046Phase 2
• A Clinical Study to Evaluate the Safety and Effectiveness of Inclisiran Sodium in Indian Patients With Primary Hypercholesterolemia or Mixed DyslipidemiaCompletedNCT06386419Phase 4
• In Silico Study Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Patients With Established Cardiovascular DiseaseCompletedNCT05974345
• A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.Active, not recruitingNCT05739383Phase 3
• Study Evaluating LDL-C Change and Adherence to Inclisiran Lipid-lowering Therapy in ASCVDActive, not recruitingNCT05399992
• Study to Assess the Real World Effectiveness of Inclisiran in Chinese Adult Patients With Primary Hypercholesterolemia or Mixed DyslipidemiaCompletedNCT05118230
• Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular DiseaseActive, not recruitingNCT05030428Phase 3
• Study of Efficacy and Safety of Inclisiran in Asian Participants With Atherosclerotic Cardiovascular Disease (ASCVD) or ASCVD High Risk and Elevated Low Density Lipoprotein Cholesterol (LDL-C)Active, not recruitingNCT04765657Phase 3
• Safety and Pharmacokinetis of TAP311 in Dyslipidemic PatientsCompletedNCT01632358Phase 1
• Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TAP311 in Healthy Subjects and Dyslipidemic PatientsCompletedNCT01487460Phase 1
• Reducing the Overall Risk Level in Patients Suffering From Metabolic SyndromeCompletedNCT00821574Phase 4
• Efficacy and Safety of Valsartan and the Combination of Valsartan and SimvastatinCompletedNCT00385931Phase 3
• Efficacy of Fluvastatin and Fenofibrate in Comparison to Simvastatin and Ezetimibe in Patients With Metabolic SyndromeCompletedNCT00385658Phase 4
• Efficacy and Safety of Fluvastatin or Valsartan and Their Combination in Dyslipidemic Patients With Hypertension and Endothelial DysfunctionCompletedNCT00171327Phase 4
• Efficacy and Safety Study of Fluvastatin and Ezetimibe Combined Versus Fluvastatin AloneCompletedNCT00171288Phase 3
• Trial to Evaluate the Efficacy of Fluvastatin on Certain MarkersCompletedNCT00171262Phase 4
• Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial HypercholesterolemiaCompletedNCT00171236Phase 3
• Fluvastatin in Adults With Dislipidemia With History of Muscle ProblemsCompletedNCT00125125Phase 4