Novartis: Anemia, Aplastic trials

The registry lists 14 Anemia, Aplastic studies with Novartis as lead sponsor. 2 are open to participants now and 7 have results posted.

Phase 2 7Phase 4 2No phase 5(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Revolade Tablets Specified Drug-use SurveyRecruitingNCT06287268
• Managed Access Programs for ETB115, EltrombopagAvailableNCT04837703
• Combination of Eltrombopag With Immunosuppressive Therapy in East-Asian Patients With Severe Aplastic AnemiaCompletedNCT04328727Phase 2Results posted
• Study Assessed the Safety and Efficacy of Eltrombopag in Chinese Refractory or Relapsed Severe Aplastic Anemia (SAA) Subjects.CompletedNCT03988608Phase 2Results posted
• A Phase II Dose-escalation Study Characterizing the PK of Eltrombopag in Pediatric Patients With Previously Untreated or Relapsed Severe Aplastic Anemia or Recurrent Aplastic AnemiaCompletedNCT03025698Phase 2Results posted
• Eltrombopag Combined With Cyclosporine as First Line Therapy in Patients With Severe Acquired Aplastic AnemiaCompletedNCT02998645Phase 2Results posted
• Eltrombopag in Combination With Rabbit Anti-thymocyte Globulin/Cyclosporine A in Naive Aplastic Anemia (AA) SubjectsCompletedNCT02404025Phase 2Results posted
• A Study to Assess the Safety and Efficacy of Eltrombopag in Japanese Subjects With Refractory, Moderate or More Severe Aplastic AnemiaCompletedNCT02148133Phase 2Results posted
• Safety and Efficacy of Exjade in the Treatment of Transfusion-dependent Iron Overload in Aplastic Anemia PatientsTerminatedNCT01818726Phase 4Results posted
• A Study of the Safety and Effectiveness of Eltrombopag in Combination With Immunosuppressive Therapy (IST) in Korean Pediatric Patients With Treatment Naïve Severe Aplastic AnemiaCompletedNCT07415083
• Real-world Outcomes of Aplastic Anemia Patients Treated With Eltrombopag: A Medical Claims Database StudyCompletedNCT06991894
• Effectiveness of Early Intervention in Transfusion Independent Aplastic Anemia: a Retrospective Medical Claims Database StudyCompletedNCT06669221
• Safety and Efficacy of Desferasirox in Chinese Patients With Iron Overload and Aplastic AnemiaCompletedNCT01546415Phase 4
• Study of Deferasirox in Iron Overload From Beta-thalassemia Unable to be Treated With Deferoxamine or Chronic AnemiasCompletedNCT00061763Phase 2