National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): Hepatitis trials

The registry lists 39 Hepatitis studies with National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) as lead sponsor. 0 are open to participants now and 21 have results posted.

Phase 1 2Phase 2 19Phase 3 7Phase 4 4No phase 8(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Treatment of Chronic Delta Hepatitis With Lonafarnib, Ritonavir and Lambda InterferonCompletedNCT03600714Phase 2Results posted
• Treatment of Chronic Delta Hepatitis With Lonafarnib and RitonavirCompletedNCT02511431Phase 2Results posted
• Viral Kinetics, Interferon Stimulated Genes (ISGs) and mirRNA Among Subjects Infected With Different Hepatitis C Virus Genotypes During Therapy With Sofosbuvir and GS-5816CompletedNCT02468648Phase 2Results posted
• Add-on Peginterferon Following Nucleos(t)Ide Analogue TreatmentCompletedNCT02364336Phase 2Results posted
• Evaluation of Safety, Tolerability, and Antiviral Activity of Chlorcyclizine HCl in Patients With Chronic Hepatitis CCompletedNCT02118012Phase 1/2Results posted
• New Treatment Response in People With and Without Cirrhosis From Chronic Hepatitis CCompletedNCT01888900Phase 2Results posted
• Lonafarnib for Chronic Hepatitis DCompletedNCT01495585Phase 2Results posted
• Combination Therapy of Pegylated Interferon Alfa-2a and Tenofovir Versus Tenofovir Monotherapy in Chronic Hepatitis BCompletedNCT01369212Phase 3Results posted
• Combination Entecavir and Peginterferon Therapy in HBeAg-Positive Immune-Tolerant Adults With Chronic Hepatitis BTerminatedNCT01369199Phase 3Results posted
• Entecavir/Pegylated Interferon in Immune Tolerant Children With Chronic Hepatitis B Virus (HBV) InfectionCompletedNCT01368497Phase 3Results posted
• High-Dose Ribavirin and Peginterferon to Treat Chronic Hepatitis C Genotype 1CompletedNCT00735969Phase 2Results posted
• Tenofovir Alone Versus Tenofovir With Emtricitabine to Treat Chronic Hepatitis BTerminatedNCT00524173Phase 2Results posted
• S-Adenosyl Methionine (SAMe) to Treat Patients With Chronic Hepatitis CCompletedNCT00475176Phase 2Results posted
• PEDS-C: Pegylated Interferon +/- Ribavirin for Children With Hepatitis CCompletedNCT00100659Phase 3Results posted
• Treating Nonalcoholic Steatohepatitis (NASH) With MetforminCompletedNCT00063232Phase 2Results posted
• Treating Nonalcoholic Steatohepatitis With PioglitazoneCompletedNCT00062764Phase 2Results posted
• Low-Dose Peginterferon and Ribavirin to Treat Chronic Hepatitis C in Patients Infected With HCV Genotype 2 or 3CompletedNCT00056862Phase 4Results posted
• Pegylated Interferon and Ribavirin to Treat Chronic Hepatitis C With and Without Kidney DiseaseCompletedNCT00028093Phase 4Results posted
• Pegylated Interferon to Treat Chronic Hepatitis DCompletedNCT00023322Phase 2Results posted
• Lamivudine and Adefovir to Treat Chronic Hepatitis BCompletedNCT00023309Phase 2Results posted
• Long Term Interferon for Patients Who Did Not Clear Hepatitis C Virus With Standard TreatmentCompletedNCT00006164Phase 3Results posted
• Peginterferon Lambda and Lonafarnib Boosted With Ritonavir 48-Week Combination Therapy for Delta HepatitisWithdrawnNCT05953545Phase 2
• Hepatitis B Immune Globulin (HBIg) to Restore Immune Control in People With Chronic Hepatitis BWithdrawnNCT03575208Phase 2
• Hepatitis B Reactivation During Treatment With Direct-Acting Antiviral Agents for Chronic Hepatitis C InfectionCompletedNCT03248622
• Duration of Long-term Immunity After Hepatitis B Virus ImmunizationCompletedNCT01182311
• Viral Kinetics and Liver Gene Expression in Response to Ribavirin and Peginterferon Therapy of Chronic Hepatitis CCompletedNCT00718172Phase 1
• Hepatitis C Treatment and AtherosclerosisCompletedNCT00659256
• Long-Term Lamivudine Therapy for Chronic Hepatitis BCompletedNCT00120354Phase 4
• Hepatitis C: Grading and Staging by MRCompletedNCT00059397
• Prevention of Recurrent Hepatitis B After Liver TransplantationCompletedNCT00059267
• Treatment of Cholestatic Pruritus With SertralineCompletedNCT00058903Phase 2
• Hepatitis C Antiviral Resistance in African-AmericansCompletedNCT00038974Phase 3
• Gamma Interferon Therapy for Chronic Hepatitis CCompletedNCT00028275Phase 2
• Immune Response to Hepatitis C VirusCompletedNCT00006301
• Genetics of Hepatitis C Virus InfectionCompletedNCT00005657
• History of Hepatitis C in Volunteer Blood DonorsCompletedNCT00001982
• Long-Term Therapy With Ribavirin for Chronic Hepatitis CCompletedNCT00001854Phase 4
• Combination Drug Therapy for Patients With Hepatitis CCompletedNCT00001729Phase 3
• Lamivudine for Chronic Hepatitis BCompletedNCT00001457Phase 2