National Institute of Allergy and Infectious Diseases (NIAID): Mycobacterium Infections trials

The registry lists 24 Mycobacterium Infections studies with National Institute of Allergy and Infectious Diseases (NIAID) as lead sponsor. 2 are open to participants now and 0 have results posted.

Phase 1 4Phase 2 7Phase 3 2No phase 12(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Training Protocol on the Natural History of TuberculosisRecruitingNCT01212003
• Study of Mycobacterial InfectionsRecruitingNCT00018044
• Immune Responses to Mycobacterium Tuberculosis (Mtb) in People With Latent Tuberculosis Infection With or Without Concomitant Helminth InfectionTerminatedNCT02225158
• Sildenafil for PNTM InfectionCompletedNCT01853540Phase 1/2
• Effect of Filarial Infection on Immune Responses in Latent TuberculosisCompletedNCT01547884
• A Cluster-Randomized Trial of DOTS vs DOTS Plus Active Case FindingCompletedNCT00414882
• Immune Responses to Mycobacterium TuberculosisCompletedNCT00340990
• Adjuvant Cytokine Therapy to Treat Pulmonary Mycobacterium Avium Complex InfectionCompletedNCT00111397Phase 1
• A Randomized, Double-Blinded, Placebo-Controlled, Phase II Inhaled Interferon Gamma-1b and Antimycobacterials to Treat Pulmonary Mycobacterium Avium Complex InfectionsCompletedNCT00021567Phase 2
• Interleukin-12 in the Treatment of Severe Nontuberculous Mycobacterial InfectionsCompletedNCT00001911Phase 1
• Subcutaneously Administered Interleukin-12 Therapy in HIV-Infected Patients With Disseminated Mycobacterium Avium Complex InfectionCompletedNCT00001763Phase 1
• Treatment of Non-Tuberculous Mycobacterial Infections With Interferon GammaCompletedNCT00001318Phase 2
• A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients With AIDSCompletedNCT00001058Phase 2
• Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium Avium Complex Disease (MAC) Plus AIDSCompletedNCT00001047Phase 3
• Evaluation of Treatment for Mycobacterium Avium Complex (MAC) Infection in HIV-Infected PatientsCompletedNCT00001039Phase 2
• The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected PatientsCompletedNCT00001030Phase 3
• The Safety and Effectiveness of Rifabutin, Combined With Clarithromycin or Azithromycin, in HIV-Infected PatientsCompletedNCT00001023Not applicable
• A Study to Evaluate the Effects of Azithromycin on MAC Disease Prevention in HIV-Positive PatientsCompletedNCT00000947Not applicable
• Effects of MAC Preventive Therapy on Disease-Causing Bacteria in HIV-Infected Patients: A Substudy of CPCRA 048CompletedNCT00000933
• A Study to Learn More About MAC Disease and the Use of Anti-HIV Drugs in Patients With Advanced HIV InfectionCompletedNCT00000895Not applicable
• Long-Term Assessment for Metabolic, Cardiovascular and Neurologic Problems in HIV-Infected Patients With Increased CD4 Cells Counts Following Anti-HIV TherapyCompletedNCT00000883Not applicable
• The Effects of Treatment for Mycobacterium Avium Complex (MAC) on the Cells of HIV-Infected PatientsCompletedNCT00000860
• A Phase II Safety and Efficacy Study of Clarithromycin in the Treatment of Disseminated M. Avium Complex (MAC) Infections in Patients With AIDSCompletedNCT00000644Phase 2
• A Phase II/III Trial of Rifampin, Ciprofloxacin, Clofazimine, Ethambutol, and Amikacin in the Treatment of Disseminated Mycobacterium Avium Infection in HIV-Infected Individuals.CompletedNCT00000641Phase 2