National Institute of Allergy and Infectious Diseases (NIAID): Lyme Disease trials

The registry lists 12 Lyme Disease studies with National Institute of Allergy and Infectious Diseases (NIAID) as lead sponsor. 3 are open to participants now and 1 have results posted.

Early Phase 1 1Phase 1 1Phase 2 1Phase 3 3No phase 7(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Human Immune Response to Ixodes Scapularis Tick BitesRecruitingNCT05036707Phase 1/2
• Evaluation, Treatment, and Follow-up of Patients With Lyme DiseaseRecruitingNCT00028080
• A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients With Suspected Post Treatment Lyme Disease Syndrome and Selected Control PopulationsRecruitingNCT00001539
• Xenodiagnosis After Antibiotic Treatment for Lyme DiseaseCompletedNCT02446626Not applicableResults posted
• Evaluation and Follow-up of People With Tick-borne DiseasesWithdrawnNCT04318925
• CD8 Reactivity to Microorganisms in Blood and Breast MilkTerminatedNCT03084614
• Searching for Persistence of Infection in Lyme DiseaseCompletedNCT01143558Early Phase 1
• Investigation of Southern Tick-Associated Rash Illness (STARI)TerminatedNCT00358761
• Analysis of Lyme Disease LesionsCompletedNCT00132327
• A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of the Safety and Efficacy of Ceftriaxone and Doxycycline in the Treatment of Patients With Seropositive Chronic Lyme DiseaseCompletedNCT00001101Phase 3
• A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of the Safety and Efficacy of Ceftriaxone and Doxycycline in the Treatment of Patients With Seronegative Chronic Lyme DiseaseCompletedNCT00000938Phase 3
• Study and Treatment of Post Lyme Disease (STOP-LD)CompletedNCT00000937Phase 3