National Institute of Allergy and Infectious Diseases (NIAID): Hepatitis C trials

The registry lists 36 Hepatitis C studies with National Institute of Allergy and Infectious Diseases (NIAID) as lead sponsor. 1 are open to participants now and 15 have results posted.

Phase 1 9Phase 2 18Phase 3 1Phase 4 2No phase 10(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIVRecruitingNCT07040319Phase 1/2
• Evaluating the Safety and Effectiveness of Interferon-Free Treatment of Hepatitis C Virus Infection in HIV-Coinfected Adults on Antiretroviral TherapyTerminatedNCT02194998Phase 2Results posted
• Study of A Combination Pill With GS-7977 and GS-5885 for Hepatitis C in People With HIVCompletedNCT01878799Phase 2Results posted
• Combination Therapy for Chronic Hepatitis C InfectionCompletedNCT01805882Phase 2Results posted
• Evaluating the Effectiveness of Boceprevir, Pegylated-Interferon Alfa 2b and Ribavirin in Treating Hepatitis C Virus (HCV) Infection in Adults With HIV and HCV InfectionCompletedNCT01482767Phase 3Results posted
• GS-7977 With Ribavirin for Hepatitis C (SPARE)CompletedNCT01441180Phase 1/2Results posted
• Staged Phase I/II Hepatitis C Prophylactic VaccineCompletedNCT01436357Phase 1/2Results posted
• Open Label Study to Evaluate Chronic Hepatitis C Treatment in Latino Subjects With and Without HIV Co-infectionTerminatedNCT01182298Results posted
• Nitazoxanide Plus Ribavirin and Peginterferon for Therapy of Treatment Naive HCV Genotype 1 and HIV Coinfected SubjectsCompletedNCT00991289Phase 2Results posted
• Pioglitazone to Treat Fatty Liver in Patients With HIV and Hepatitis C InfectionsTerminatedNCT00742326Phase 4Results posted
• Anti-D for Treating Thrombocytopenia in Adults Infected With Hepatitis C Virus With or Without HIV Co-InfectionTerminatedNCT00239733Phase 4Results posted
• Gradual Withdrawal of Immune System Suppressing Drugs in Patients Receiving a Liver TransplantCompletedNCT00135694Phase 2Results posted
• Peginterferon Alpha-2a and Ribavirin to Treat Hepatitis C in HIV-infected PatientsCompletedNCT00085917Phase 2Results posted
• Pegylated Interferon Alfa-2a Maintenance Therapy and Liver Disease Progression in People Infected With Both HIV and Hepatitis C Virus (HCV)CompletedNCT00078403Phase 2Results posted
• Rituximab to Treat Hepatitis C-Associated Cryoglobulinemic VasculitisCompletedNCT00029107Phase 2Results posted
• Peginterferon Alpha-2b And Ribavirin to Treat Hepatitis C in HIV-Infected PatientsCompletedNCT00018031Phase 2Results posted
• Evaluating the Safety of ITX 5061 in Treatment-Naive Hepatitis C (HCV)-Infected AdultsCompletedNCT01165359Phase 1
• Chiron Corp HCV E1/E2 VaccineCompletedNCT00500747Phase 1
• TG4040 in Patients With Chronic HCVWithdrawnNCT00449124Phase 1
• Determining Responses to Two Different Vaccines in HIV and HCV Infected IndividualsCompletedNCT00393276Phase 1
• Interferon-Induced Gene Expression in Liver Cells and Peripheral Blood LymphocytesCompletedNCT00324389Phase 2
• Effects of Anti-HIV Therapy on Treatment for Hepatitis C in HCV/HIV Infected AdultsCompletedNCT00100581Not applicable
• Leukapheresis for Research on HCV-Coinfected PatientsCompletedNCT00076427
• Racial Difference in HCV/Host InteractionsCompletedNCT00071916
• Zidovudine Levels in HIV Infected Patients Being Treated for HCVCompletedNCT00059358Phase 1/2
• Treatment of Hepatitis C in Hemophilic Patients With HIVCompletedNCT00055341Phase 2
• Treatment of Hepatitis in Patients Who Are Triple-Infected With HIV, Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV)WithdrawnNCT00051077Phase 2
• Prevalence of Hepatitis C Virus Infection in HIV-Infected ChildrenCompletedNCT00037076
• The Impact of HAART on Response to Hepatitis C Treatment in Patients Taking Peginterferon Alpha-2b and RibavirinCompletedNCT00031343Phase 2
• Effect of a Change in HIV Therapy on Liver Steatosis, Inflammation, and FibrosisWithdrawnNCT00023218Not applicable
• Effects of Ribavirin on Zidovudine or StavudineCompletedNCT00021632
• Interleukin-2 (IL-2), Pegylated Interferon (PEG-IFN Alfa-2b), and Ribavirin (RBV) Treatment in Patients With Hepatitis C and HIV CoinfectionCompletedNCT00015652Not applicable
• A Comparison of the Effectiveness, Safety, and Tolerability of Two Different Hepatitis C Treatments in Patients Infected With Both HIV and Hepatitis C Virus (HCV)CompletedNCT00008463Phase 2
• Comparing Single Photon Emission Computed Tomography (SPECT) and Liver Biopsy to Evaluate the Liver in Patients With HIV and Hepatitis C VirusCompletedNCT00006643
• A Study to Evaluate the Effects of Anti-HIV Drugs in HIV-Positive Patients Who Also Have Hepatitis C InfectionCompletedNCT00001117
• The Safety and Effectiveness of a Two-Drug Combination in the Treatment of Patients With Hepatitis C Plus Advanced HIV InfectionsCompletedNCT00001035Phase 1