National Institute of Allergy and Infectious Diseases (NIAID): Gonorrhea trials

The registry lists 15 Gonorrhea studies with National Institute of Allergy and Infectious Diseases (NIAID) as lead sponsor. 1 are open to participants now and 10 have results posted.

Phase 1 7Phase 2 3Phase 3 1Phase 4 1No phase 3(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African WomenNot yet recruitingNCT07884240Phase 3
• Experimental Human Infection With Neisseria Gonorrhoeae (LptA Trial)CompletedNCT04870138Phase 1Results posted
• Mucosal Immunity Against Neisseria Gonorrhoeae After 4CMenB VaccinationCompletedNCT04722003Phase 2Results posted
• Clinical Study of a Diagnostic Device for NG, TV and CT in WomenCompletedNCT03852316Not applicableResults posted
• Experimental Human Infection With Neisseria GonorrhoeaeCompletedNCT03840811Phase 1Results posted
• Thorough QT/QTC (TQT) Clinical Trial to Evaluate the Effect of Zoliflodacin on Cardiac Repolarization in Healthy Male and Female SubjectsCompletedNCT03613649Phase 1Results posted
• Clinical Study of a Single-Use, Point-of-Care Molecular Diagnostic Device for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) Utilizing Vaginal SwabsTerminatedNCT03596151Not applicableResults posted
• A Study to Evaluate the Safety, Tolerability and Plasma PK of a Single Oral Dose of Zoliflodacin in Healthy Male and Female VolunteersCompletedNCT03404167Phase 1Results posted
• Clinical Validation of a Molecular Test for Ciprofloxacin-Susceptibility in Neisseria GonorrhoeaeCompletedNCT02961751Not applicableResults posted
• Randomized, Open-label Phase 2 Study of Oral AZD0914 in the Treatment of GonorrheaCompletedNCT02257918Phase 2Results posted
• Efficacy of Combination Therapies for Gonorrhea TreatmentCompletedNCT00926796Phase 4Results posted
• Safety and Efficacy Study of Meningococcal Group B Vaccine rMenB+OMV NZ (Bexsero) to Prevent Gonococcal InfectionCompletedNCT04350138Phase 2
• Cefixime / Azithromycin pK StudyCompletedNCT02708992Phase 1
• Genitourinary and Pharyngeal Pharmacokinetics of SolithromycinCompletedNCT02348424Phase 1
• The Pharmacokinetics of Extended Duration High-dose Cefixime for the Decreased Susceptibility of Neisseria Gonorrhoeae: A Phase I Pilot StudyCompletedNCT01949363Phase 1