National Institute of Allergy and Infectious Diseases (NIAID): Asthma trials

The registry lists 35 Asthma studies with National Institute of Allergy and Infectious Diseases (NIAID) as lead sponsor. 6 are open to participants now and 10 have results posted.

Early Phase 1 1Phase 1 6Phase 2 9Phase 4 2No phase 20(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Firefighter's Longitudinal Airway and Respiratory Exposome/Multiome Study (FLARES)Enrolling by invitationNCT07867184
• Microbiome and Atopy in MaliRecruitingNCT07051902
• A Biorepository of Multiple Allergic Diseases (MADREP) With Longitudinal Follow-UpRecruitingNCT06732414
• Protocol CAUSE-03 / CHEETAHRecruitingNCT06136091
• Registry of Asthma Characterization and Recruitment 3 (RACR3)RecruitingNCT05272241
• Activation and Function of Eosinophils in Conditions With Blood or Tissue EosinophiliaRecruitingNCT00001406
• A Trial of Mepolizumab Adjunctive Therapy for the Prevention of Asthma Exacerbations in Urban ChildrenCompletedNCT03292588Phase 2Results posted
• Cockroach Nasal Allergen Challenge PilotCompletedNCT02710136Phase 1Results posted
• Subcutaneous Immunotherapy for Mouse in AdultsCompletedNCT02532179Phase 1/2Results posted
• Preventative Omalizumab or Step-up Therapy for Severe Fall ExacerbationsCompletedNCT01430403Phase 4Results posted
• Biomarkers of Cockroach Sublingual Immunotherapy 2CompletedNCT01380327Phase 1/2Results posted
• Development of Cockroach Immunotherapy by the Inner-City Asthma ConsortiumCompletedNCT01221285Phase 1Results posted
• Biomarker-based Cockroach Sublingual Immunotherapy Study (BioCSI)CompletedNCT00829985Phase 1/2Results posted
• Sublingual Cockroach Safety in Adults With Cockroach Allergy & Perennial Allergic Rhinitis With or Without AsthmaCompletedNCT00434421Phase 1Results posted
• Inner-City Anti-IgE Therapy for AsthmaCompletedNCT00377572Phase 4Results posted
• Promoting Tolerance to Common Allergens in High-Risk Children: Global Prevention of Asthma in Children (GPAC) StudyCompletedNCT00346398Phase 2Results posted
• Prevention of Asthma Exacerbations Using Dupilumab in Urban Children and AdolescentsActive, not recruitingNCT05347771Phase 2
• Vaginal Microbiome Exposure and Immune Responses in C-section InfantsActive, not recruitingNCT03567707Early Phase 1
• Registry for Asthma Characterization and Recruitment 2CompletedNCT02513264
• Mechanisms Underlying Asthma Exacerbations Prevented and Persistent With Immune-Based TherapyCompletedNCT02502890
• Human Rhinovirus Infection and Airway Remodeling MediatorsTerminatedNCT01847768Not applicable
• Asthma Phenotypes in the Inner CityCompletedNCT01383941
• The Role of Epigenetics in Inner City AsthmaCompletedNCT01382836
• ICATA Asthma Mechanistic StudyCompletedNCT00377390
• Treatment of Ragweed-Allergic Asthma With an Immunostimulatory DrugTerminatedNCT00318747Phase 2
• Methods of Determining Asthma Severity in ChildrenCompletedNCT00132834
• Urban Environmental Factors and Childhood AsthmaCompletedNCT00114881
• Evaluation of an Asthma Treatment Strategy Based on Exhaled Nitric Oxide Measurements in AdolescentsCompletedNCT00114413Not applicable
• Genetic Risk Factors for Severe AsthmaCompletedNCT00090740
• Exhaled Breath Condensate as a Measure of Airway Inflammation in Children With AsthmaCompletedNCT00078208
• Recombinant Human IL-4 Receptor Used in Treatment of AsthmaCompletedNCT00017693Phase 2
• Phase II Efficacy Study of Aerosolized Recombinant Human IL-4 Receptor in AsthmaCompletedNCT00001909Phase 2
• T Cell Cytokine Changes During IL-4 Receptor Treatment for AsthmaCompletedNCT00001908
• Assessment of Lung Inflammation in Patients With Atopic Asthma Using Positron Emission TomographyCompletedNCT00001759
• Role of T-Cells in AsthmaCompletedNCT00001408