National Cancer Institute, Naples: Colorectal Neoplasms trials

The registry lists 15 Colorectal Neoplasms studies with National Cancer Institute, Naples as lead sponsor. 5 are open to participants now and 1 have results posted.

Phase 2 8Phase 3 2No phase 5(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• STREAM-2: Second-line Treatment With REgorafenib in Advanced RAS-Mutant Colorectal CancerRecruitingNCT07213570Phase 2
• ValproIc Acid to Potentiate Anti-EGFR Treatment Efficacy and Prevent/Revert Resistance in Colorectal CancerRecruitingNCT06714357Phase 2
• Intermittent or Continuous Panitumumab Plus FOLFIRI for Left Sided RAS/B-RAF Wild-type Metastatic Colorectal CancerRecruitingNCT06509126Phase 3
• PRELUDE-1 (Prospective Evaluation of Radiotherapy-induced Biologic Effects in Colorectal Cancer Oligometastatic Patients with LUng-limited Disease: Evolution of Cancer Genetics and Regulatory Immune Cells)RecruitingNCT04854213Not applicable
• Study of Folfiri/Cetuximab in FcGammaRIIIa V/V Stage IV Colorectal Cancer PatientsRecruitingNCT03874026Phase 2
• Optimization of Bevacizumab Scheduling With Chemotherapy for Metastatic Colorectal CancerCompletedNCT01718873Phase 3Results posted
• Intermittent or Continuous Panitumumab Plus FOLFIRI for RAS/B-RAF Wild-type Metastatic Colorectal CancerCompletedNCT04425239Phase 2
• Aflibercept or Bevacizumab as Second-line Treatment of RAS Mutated Metastatic Colorectal CancerStatus unknownNCT04397601
• Valproic Acid in Combination With Bevacizumab and Oxaliplatin/Fluoropyrimidine Regimens in Patients With Ras-mutated Metastatic Colorectal CancerStatus unknownNCT04310176Phase 2
• REINFORCEMENT ANASTOMOSIS WITH Modified Cyanacrylate IN Patients Undergoing to Oncologic Colorectal Surgery With Colorectal AnastomosisStatus unknownNCT03380858
• Regorafenib Monotherapy as Second-line Treatment of Patients With RAS-mutant Advanced Colorectal CancerStatus unknownNCT02619435Phase 2
• PET/CT Scan as a Tool to Rationalize the Treatment of Patients With Advanced ColoRectal Cancer Undergoing First-line Medical TreatmentStatus unknownNCT02618850Not applicable
• A Phase 2 Study of Panitumumab in Patients With Cetuximab-refractory Metastatic Colorectal CancerStatus unknownNCT01801904Phase 2
• Observational Study on Treatment of Metastatic Colorectal Cancer and the Role of K-RasStatus unknownNCT01651013
• Second Look Laparoscopy in Colorectal CancerStatus unknownNCT01628211Phase 2