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Mighty Therapeutics clinical trials
Also known as Stealth BioTherapeutics.
Part of Morningside Venture (I) Investments Limited, which holds 66.8% as of 2022-05-31. Source
The registry lists 29 studies whose lead sponsor is Mighty Therapeutics. 2 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 16, 2026.
Keep track of what changes. Save the Mighty Therapeutics studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesRegistry sponsor names on this page
Each name exactly as ClinicalTrials.gov lists it, and how it relates to Mighty Therapeutics.
- Stealth BioTherapeutics Inc.29 studiesSame company
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Studies
Recruiting first, then most recently updated. Showing 29 of 29.
- An Intermediate Size Expanded Access Protocol of ElamipretideAvailableNCT04689360
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- Clinical Trial in Patients With Barth Syndrome- 4TAZPowerRecruitingNCT07531251Phase 4
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD)Active, not recruitingNCT06373731Phase 3
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD)CompletedNCT05162768Phase 3
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- ReCLAIM-2 Study to Evaluate Safety,Efficacy & Pharmacokinetics of Elamipretide in Subjects With AMD With Non-central GACompletedNCT03891875Phase 2
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- A Trial to Evaluate Safety, Tolerability and Efficacy of Elamipretide in Subjects With Barth SyndromeCompletedNCT03098797Phase 2/3
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- A Trial to Evaluate Safety and Efficacy of Elamipretide Primary Mitochondrial Myopathy Followed by Open-Label ExtensionTerminatedNCT03323749Phase 3
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM)TerminatedNCT02976038Phase 2
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic NeuropathyCompletedNCT02693119Phase 2
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for the Treatment of Fuchs' Corneal Endothelial Dystrophy (FCED)CompletedNCT02653391Phase 1/2
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects With Intermediate Age-Related Macular DegenerationCompletedNCT02848313Phase 1
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- Effects of Intravenous Bendavia™ on Reperfusion Injury in Patients Undergoing Angioplasty of the Renal ArteryTerminatedNCT01755858Phase 1/2
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- A Phase 2 Study to Evaluate the Cardiac and Renal Effects of Short Term Treatment With Elamipretide in Patients Hospitalized With Congestion Due to Heart FailureCompletedNCT02914665Phase 2
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- Safety, Tolerability, Efficacy of MTP-131 for Treatment of Mitochondrial Disease in Subjects From the MMPOWER StudyCompletedNCT02805790Phase 2
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- A Phase 2 Study to Evaluate the Impact of MTP-131 (Bendavia™) on Skeletal Muscle Function in ElderlyCompletedNCT02245620Phase 2
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- Evaluation of Myocardial Effects of MTP-131 for Reducing Reperfusion Injury in Patients With Acute Coronary EventsCompletedNCT01572909Phase 2
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- Effect of Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Reduced Ejection FractionCompletedNCT02788747Phase 2
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- Safety, Tolerability, and Efficacy of MTP-131 for the Treatment of Mitochondrial MyopathyCompletedNCT02367014Phase 1/2
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- An Observational Study of Patients With Primary Mitochondrial Disease (SPIMM-300)CompletedNCT03048617
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- A Study to Evaluate the Effects of 4 Weeks Treatment With Subcutaneous Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Preserved Ejection FractionCompletedNCT02814097Phase 2
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal FunctionCompletedNCT02436447Phase 1
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- A Study of MTP-131 Topical Ophthalmic Solution in Subjects With Diabetic Macular Edema and Non-Exudative Intermediate Age-related Macular DegenerationCompletedNCT02314299Phase 1/2
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- A Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of Bendavia™ (MTP-131) in Patients With Heart FailureWithdrawnNCT02388529Phase 1
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- A Study Investigating the Safety, Tolerability, and Pharmacokinetics of MTP-131 in Subjects With Congestive Heart FailureCompletedNCT02388464Phase 1
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- Safety and Pharmacokinetic (PK) Study of Oral Bendavia Administered for 7 DaysCompletedNCT01786915Phase 1
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- A Phase 1 Study Examining the Pharmacokinetics and Tolerability of a Single Oral Dose of Bendavia (MTP-131)CompletedNCT01754818Phase 1
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- Study to Assess the Pharmacodynamic Effects of Unfractionated Heparin (UFH) in Healthy Volunteers With and Without BendaviaCompletedNCT01513200Phase 1
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- The Impact of Intravenous Bendavia™ on Endothelial Reactivity Dysfunction in Cigarette SmokingCompletedNCT01518985Phase 1
Sponsor listed in the registry: Stealth BioTherapeutics Inc.
- Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of Intravenous (IV) Infusion of MTP-131 (Bendavia™) in Healthy AdultsCompletedNCT01115920Phase 1
Sponsor listed in the registry: Stealth BioTherapeutics Inc.