Memorial Sloan Kettering Cancer Center: Sarcoma trials

The registry lists 58 Sarcoma studies with Memorial Sloan Kettering Cancer Center as lead sponsor. 8 are open to participants now and 15 have results posted.

Early Phase 1 1Phase 1 9Phase 2 34Phase 3 3No phase 14(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study of Pembrolizumab in People With Ultra-Rare SarcomasRecruitingNCT07089992Phase 2
• Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With SarcomaRecruitingNCT06129903Not applicable
• A Study Involving Collection of Samples and Data From Sarcoma Patients Receiving ImmunotherapyEnrolling by invitationNCT06113315
• A Study of CRD3874-SI in People With Solid TumorsRecruitingNCT06021626Phase 1
• A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft TissueRecruitingNCT05837767Not applicable
• Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue SarcomaRecruitingNCT04577014Phase 1/2
• A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or LegRecruitingNCT04332874Phase 2
• Novel Biochemical and Molecular Determinants for Soft Tissue SarcomaRecruitingNCT00579566
• A Study of XmAb23104 in People With SarcomaTerminatedNCT05879185Phase 2Results posted
• A Study of Epacadostat, an IDO1 Inhibitor, in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced SarcomaActive, not recruitingNCT03414229Phase 2Results posted
• A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced SarcomaActive, not recruitingNCT03069378Phase 2Results posted
• Whole Lung IMRT in Children and Adults With Synovial Sarcoma and Lung MetastasesCompletedNCT02181829Phase 2Results posted
• Cyclophosphamide, Topotecan, and Bevacizumab (CTB) in Patients With Relapsed/Refractory Ewing's Sarcoma and NeuroblastomaCompletedNCT01492673Phase 2Results posted
• Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS)TerminatedNCT01418001Phase 1/2Results posted
• Clinical Study of Vorinostat in Combination With Etoposide in Pediatric Patients < 21 Years at Diagnosis With Refractory Solid TumorsCompletedNCT01294670Phase 1/2Results posted
• Gemcitabine and Docetaxel With Bevacizumab in Selected Sarcoma SubtypesCompletedNCT00887809Phase 2Results posted
• Sorafenib and Dacarbazine in Soft Tissue SarcomaCompletedNCT00837148Phase 2Results posted
• Phase II Trial of Stereotactic Radiosurgery Boost Following Surgical Resection for Brain MetastasesCompletedNCT00587964Phase 2Results posted
• Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent SarcomasCompletedNCT00474994Phase 2Results posted
• Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal CancerCompletedNCT00445965Phase 2Results posted
• Busulfan, Melphalan, and Thiotepa Followed By a Donor Stem Cell Transplant in Treating Patients With High-Risk Ewing's TumorsCompletedNCT00357396Phase 2Results posted
• Valganciclovir in Treating Patients With Classic Non-HIV-Associated Kaposi's SarcomaCompletedNCT00096538Not applicableResults posted
• Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid TumorsCompletedNCT00024258Phase 2Results posted
• A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated LiposarcomaActive, not recruitingNCT05886634Phase 2
• A Study of Niraparib in People With Soft Tissue Sarcoma Who Have Changes in Their Tumor DNAActive, not recruitingNCT05515575Phase 2
• Dose Reduction of Postoperative Radiation for Soft Tissue Sarcoma of the Arms and LegsActive, not recruitingNCT04288375Phase 2
• Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic SarcomasCompletedNCT04242238Phase 1
• A Study of NKTR-214 in Combination With Nivolumab in Patients With Metastatic and/or Locally Advanced SarcomaActive, not recruitingNCT03282344Phase 2
• Study of Abemaciclib in Dedifferentiated LiposarcomaActive, not recruitingNCT02846987Phase 2
• Using a Patient-Centered mHealth Intervention to Improve Adherence to Oral Anticancer MedicationsCompletedNCT02833246Not applicable
• PET Imaging of Solid Tumors Using 124I-Humanized 3F8: A Pilot StudyActive, not recruitingNCT02307630Not applicable
• PET Imaging of Cancer Patients Using [18F]-SKI-249380, a Radiolabeled Dasatinib-DerivativeCompletedNCT01916135Phase 1
• Randomized Study Comparing Two Dosing Schedules for Hypofractionated Image-Guided Radiation TherapyActive, not recruitingNCT01223248Phase 3
• Irinotecan, Temozolomide and Bevacizumab in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Newly Diagnosed Patients With Desmoplastic Small Round Cell TumorActive, not recruitingNCT01189643Early Phase 1
• Genomic Structural Variation in Cancer SusceptibilityActive, not recruitingNCT00996710
• Application of Magnetic Resonance Fat-Free ImagingTerminatedNCT00944476
• Environmental Pollutants and the Risk of Soft Tissue Sarcoma: A Pilot StudyCompletedNCT00611078
• Dynamic Contrast Enhanced MRI(DCE-MRI)of Bone TumorsCompletedNCT00598741Not applicable
• AIDS and Cancer Specimen Bank (ACSB)CompletedNCT00587912
• Collection of Tissue & Blood From Patients w/ Benign & Malignant Tumors of the Soft Tissue & Gastrointestinal TractActive, not recruitingNCT00582647
• Spectroscopy With Surface Coils and DecouplingCompletedNCT00581815Phase 1
• Cytogenetic and Molecular Genetic Studies in Bone SarcomasCompletedNCT00579930
• Comparison of Gemcitabine v. Gemcitabine Plus Docetaxel in Unresectable Soft Tissue SarcomaCompletedNCT00142571Phase 3
• A Prospective Randomized Trial of Pre-Operative IMRT+Surgery Versus Surgery Alone For Primary Retroperitoneal SarcomaCompletedNCT00131898Phase 3
• Irinotecan and Carboplatin as Upfront Window Therapy in Treating Patients With Newly Diagnosed Intermediate-Risk or High-Risk RhabdomyosarcomaActive, not recruitingNCT00077285Phase 2
• Alanosine in Treating Patients With CancerCompletedNCT00062283Phase 2
• Doxorubicin and Bevacizumab in Treating Patients With Locally Recurrent or Metastatic Soft Tissue SarcomaCompletedNCT00052390Phase 2
• Bortezomib in Treating Patients With Advanced or Metastatic SarcomaCompletedNCT00027716Phase 2
• Ecteinascidin 743 in Treating Patients With Unresectable Advanced or Metastatic Soft Tissue SarcomaCompletedNCT00017030Phase 2
• Vaccine Therapy in Treating Patients With Recurrent Soft Tissue SarcomaCompletedNCT00005628Phase 2
• Trastuzumab in Treating Patients With Recurrent OsteosarcomaCompletedNCT00005033Phase 2
• Isolated Limb Infusion of Chemotherapy in Treating Patients With Melanoma or Soft Tissue Sarcoma of the Arm or Leg That Cannot Be Removed By SurgeryCompletedNCT00004250Phase 2
• Gemcitabine, Docetaxel, and Filgrastim in Treating Patients With Recurrent or Persistent Leiomyosarcoma or Soft Tissue SarcomaCompletedNCT00004066Phase 2
• Combination Chemotherapy and Biological Therapy in Treating Patients With High-Risk Ewing's SarcomaCompletedNCT00003667Phase 2
• Monoclonal Antibody A1G4 Plus BCG in Treating Patients With CancerCompletedNCT00003023Phase 1
• Monoclonal Antibody Therapy in Treating Patients With Leptomeningeal CancerCompletedNCT00003022Phase 1
• Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare CancerCompletedNCT00002515Phase 2
• Combination Chemotherapy and Radiation Therapy in Treating Patients With Peripheral Neuroectodermal Tumors, Ewing's Sarcoma, Wilms' Tumor, or Bone CancerCompletedNCT00002466Phase 2