Memorial Sloan Kettering Cancer Center: Neoplasm Metastasis trials

The registry lists 50 Neoplasm Metastasis studies with Memorial Sloan Kettering Cancer Center as lead sponsor. 10 are open to participants now and 10 have results posted.

Phase 1 20Phase 2 21Phase 3 1No phase 14(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• FORTRAS: A Study of MSK-TCR5 in People With Solid Tumor CancersRecruitingNCT07638371Phase 1
• A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With OsteosarcomaRecruitingNCT07477457Phase 2
• Trastuzumab Deruxtecan (T-DXd) for People With Brain CancerRecruitingNCT06058988Phase 2
• A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor CancerRecruitingNCT05859074Phase 1
• A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft TissueRecruitingNCT05837767Not applicable
• A Study of ZEN003694 in People With Squamous Cell Lung CancerRecruitingNCT05607108Phase 2
• A Study of 68Gallium PSMA-PET/CT Scans in People With Bladder Cancer or Skin CancerRecruitingNCT05562791Phase 1
• A Study of Reduced-dose Radiation in People With Metastatic Tumors With a Genetic ChangeRecruitingNCT05010031Phase 2
• A Study of Repotrectinib in Combination With Chemotherapy in Children and Young Adults With Solid Tumor CancerRecruitingNCT05004116Phase 1/2
• New MRI Biomarkers in Head and Neck CancersRecruitingNCT03483337
• Study of Palliative Radiation Therapy vs. no Palliative Radiation Therapy for Patients With High Risk Bone Metastases That Are Not Causing Significant PainCompletedNCT03523351Phase 1/2Results posted
• A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced SarcomaActive, not recruitingNCT03069378Phase 2Results posted
• Irreversible Electroporation Ablation for Colorectal Metastases to the LungCompletedNCT02461550Not applicableResults posted
• Randomized Study Comparing Local Tumor Control After Post-Operative Single-Fraction or Hypofractionated Stereotactic Radiosurgery in the Treatment of Spinal MetastasesCompletedNCT02320825Phase 3Results posted
• Buparlisib (BKM120) In Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Recurrent/Refractory Secondary Central Nervous System Lymphoma (SCNSL)CompletedNCT02301364Phase 2Results posted
• Can HER2 Targeted PET/CT Imaging Identify Unsuspected HER2 Positive Breast Cancer Metastases, Which Are Amenable to HER2 Targeted Therapy?CompletedNCT02286843Not applicableResults posted
• Whole Lung IMRT in Children and Adults With Synovial Sarcoma and Lung MetastasesCompletedNCT02181829Phase 2Results posted
• Assess the Feasibility of Cone Beam CT to Localize Liver Metastases Immediately Prior to RadiotherapyCompletedNCT00600613Not applicableResults posted
• Phase II Trial of Stereotactic Radiosurgery Boost Following Surgical Resection for Brain MetastasesCompletedNCT00587964Phase 2Results posted
• Study of Biweekly Capecitabine Dosing With Bevacizumab for the Treatment of Metastatic Breast Cancer Based Upon the Norton-Simon Mathematical ModelCompletedNCT00468585Phase 1/2Results posted
• COBRA: Cancer, Older Adults, Balance and Resistance ActivitiesActive, not recruitingNCT07011862Not applicable
• A Study of Lorlatinib in Combination With Ramucirumab in People With Lung CancerActive, not recruitingNCT06007937Phase 1/2
• A Study of AZD1390 and Stereotactic Body Radiotherapy (SBRT) for People With Metastatic Solid Tumor CancerActive, not recruitingNCT05678010Phase 1
• A Study of RP-3500 in Combination With Standard Radiation Therapy in People With Solid Tumor CancerActive, not recruitingNCT05566574Phase 1/2
• A Study of Amivantamab in People With Esophagogastric CancerActive, not recruitingNCT05117931Phase 2
• A Study of Stereotactic Body Radiotherapy (SBRT) and Surgical Stabilization for People With Cancer That Has Spread to the BoneCompletedNCT05038124Not applicable
• Study of Avelumab and/or Radiation Therapy in People With Advanced Merkel Cell CarcinomaActive, not recruitingNCT04792073Phase 2
• Chemoembolization for Lung TumorsCompletedNCT04200417Phase 1
• An Intervention to Help Patients and Caregivers Manage Stress and Improve Communication Skills When Talking About CancerActive, not recruitingNCT03794635Not applicable
• A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint InhibitorsActive, not recruitingNCT03693014Phase 2
• Study of Proton Radiation to the Brain and Spinal Cord for Patients With Leptomeningeal MetastasesCompletedNCT03520504Phase 1
• Utility of Intra-operative Image Guidance System for Missing MetastasesCompletedNCT02806037
• Intermittent High-Dose Lapatinib in Tandem With Capecitabine for HER2 Overexpressed/Amplified Metastatic Breast Cancer With Central Nervous System (CNS) MetastasesCompletedNCT02650752Phase 1
• Detection of Acid Sphingomyelinase/Ceramide Pathway Activation in Radiotherapy Patients Using Intravoxel Incoherent Motion (IVIM) Diffusion-weighted Magnetic Resonance Imaging and Serum BiomarkersWithdrawnNCT02465723Not applicable
• Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen MesothelinActive, not recruitingNCT02414269Phase 1/2
• 18F-Fluorocholine (18F-FCho) to Distinguish Necrosis From Recurrence in Brain MetastasesCompletedNCT02037945Not applicable
• Assessment of Early Treatment Response by Diffusion and Perfusion MRI in Patients With Brain MetastasisCompletedNCT01974804
• Whole Brain Radiotherapy (WBRT) With Sorafenib for Breast Cancer Brain Metastases (BCBM)CompletedNCT01724606Phase 1
• Use of a Video Decision Tool to Improve Informed Decision-Making in Hospitalized Patients Considering Palliative Radiation TherapyCompletedNCT01667965
• Lung Inflammation and Lung Metastases From Breast CancerCompletedNCT01182519
• Study Using High-Dose Single Fraction Image-Guided Radiotherapy for Metastatic Lesions to Soft Tissue Masses, Lymph Node, or BoneCompletedNCT00678158Phase 1
• Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the LiverActive, not recruitingNCT00492999Phase 2
• Xenogeneic HER2/Neu DNA Immunization for Patients With Metastatic and High Risk Breast Cancer: A Phase I Study to Assess Safety and ImmunogenicityActive, not recruitingNCT00393783Phase 1
• Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combination With Chemotherapy With/Without Bevacizumab for Hepatic Metastases From Colorectal CancerCompletedNCT00200200Phase 2
• Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal CancerCompletedNCT00059930Phase 1
• Portal Vein Embolization in Treating Patients With Liver Metastases From Primary Colorectal CancerCompletedNCT00028626Phase 2
• Gene Therapy in Treating Patients With Colon Cancer That Has Spread to the LiverCompletedNCT00012155Phase 1
• Combination Chemotherapy in Treating Patients With Unresectable Liver Metastases From Colorectal CancerCompletedNCT00008294Phase 1
• Oxaliplatin With Or Without Floxuridine and Leucovorin in Treating Patients With Metastatic Cancer of the PeritoneumCompletedNCT00005860Phase 1
• Floxuridine, Dexamethasone, and Irinotecan After Surgery in Treating Patients With Liver Metastases From Colorectal CancerCompletedNCT00003753Phase 2