Memorial Sloan Kettering Cancer Center: Carcinoma, Non-Small-Cell Lung trials

The registry lists 51 Carcinoma, Non-Small-Cell Lung studies with Memorial Sloan Kettering Cancer Center as lead sponsor. 13 are open to participants now and 10 have results posted.

Phase 1 18Phase 2 32No phase 9(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study of Tepotinib and Ivonescimab in People With Non-Small Cell Lung CancerRecruitingNCT07619339Phase 1
• A Study of Ivonescimab in People With Non-Small Cell Lung CancerRecruitingNCT07594522Phase 1/2
• A Study of Ivonescimab, Chemotherapy, and Stereotactic Radiosurgery for People With Non-Small Cell Lung CancerRecruitingNCT07535463Phase 1/2
• A Study of Ivonescimab in Combination With Dato-DXd or Osimertinib in People With Non-Small Cell Lung CancerRecruitingNCT07535437Phase 1/2
• A Study of BIO 300 and Thoracic Radiation Therapy in People With Non-Small Cell Lung Cancer and Interstitial Lung DiseaseRecruitingNCT07323732Phase 2
• Using E-Nose Technology to Track Treatment Response in People With Non-Small Cell Lung CancerRecruitingNCT07218601Phase 2
• Using Urine Samples to Identify Lung CancerRecruitingNCT06033248
• A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft TissueRecruitingNCT05837767Not applicable
• A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC)RecruitingNCT05657873Phase 2
• Extracellular Vesicles and Particles (EVP) as Biomarkers of Recurrence in Non-Small Cell Lung CancerRecruitingNCT05424029
• Osimertinib Alone or With Chemotherapy for EGFR-Mutant Lung CancersRecruitingNCT04410796Phase 2
• Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of DiseaseRecruitingNCT03808337Phase 2
• Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL ActivityRecruitingNCT01639508Phase 2
• Trial of Trametinib and Ponatinib in Patients With KRAS Mutant Advanced Non-Small Cell Lung CancerCompletedNCT03704688Phase 1/2Results posted
• Evaluate the Mediators of Sensitivity and Resistance to Nivolumab Plus Ipilimumab in Patients With Advanced NSCLCsCompletedNCT02350764Phase 2Results posted
• Calypso-based Deep Inspiration Breath Hold (DIBH) Radiation Treatments of Lung CancerCompletedNCT02111681Not applicableResults posted
• Prognostic Value of Tumor Hypoxia, as Measured by 18F-FMISO Breath Hold PET/CT, in Non-Small-Cell-Lung Cancer (NSCLC) PatientsCompletedNCT02016872Not applicableResults posted
• Bortezomib in KRAS-Mutant Non-Small Cell Lung Cancer in Never Smokers or Those With KRAS G12DCompletedNCT01833143Phase 2Results posted
• Neoadjuvant Platinum-based Chemotherapy for Patients With Resectable , Non-small Cell Lung Cancer With Switch to Chemotherapy Alternative in Nonresponders (NEOSCAN)CompletedNCT01443078Phase 2Results posted
• Ph II OSI-774 (Erlotinib,Tarceva) In Advanced Bronchioloalveolar Cell Lung CancerCompletedNCT00590902Phase 2Results posted
• Phase II Trial to Correlate Radiographic Response Induced By Gefitinib With Mutations in the Protein-Tyrosine Kinase Domain of the EGF Receptor GeneCompletedNCT00588445Phase 2Results posted
• Multimodality Treatment for Patients With Resectable Non-Small Cell Lung Cancer (NSCLC) - BEACON Study: Bevacizumab and Chemotherapy for Operable NSCLCCompletedNCT00130780Phase 2Results posted
• Gefitinib and Everolimus in Treating Patients With Stage IIIB or Stage IV or Recurrent Non-Small Cell Lung CancerCompletedNCT00096486Phase 1/2Results posted
• A Study of Trastuzumab Deruxtecan in People With Non-Small Cell Lung CancerWithdrawnNCT07428044Phase 2
• A Study of CD8+ T Cell Imaging During Treatment in People With Non-Small Cell Lung CancerCompletedNCT06863233Phase 1
• A Study Comparing Sotorasib With Durvalumab in People With Non-Small Cell Lung Cancer (NSCLC)TerminatedNCT06333678Phase 2
• A Study of Lorlatinib in Combination With Ramucirumab in People With Lung CancerActive, not recruitingNCT06007937Phase 1/2
• A Study of Local Ablative Therapy (LAT) in People With Non-Small Cell Lung Cancer (NSCLC)CompletedNCT05429320Phase 2
• A Study of Amivantamab and Lazertinib in People With Non-Small Cell Lung Cancer (NSCLC)CompletedNCT04965090Phase 2
• A Study of Canakinumab With Chemotherapy, Radiation Therapy, and Durvalumab in People With Lung CancerCompletedNCT04905316Phase 2
• Treating Early-stage Non-Small Cell Lung Cancer With Durvalumab and Radiation TherapyActive, not recruitingNCT04716946Phase 2
• Radiation Therapy to Relieve Symptoms in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)CompletedNCT04384146Phase 1
• Determining Whether Durvalumab in Combination With Radiation Therapy Can Prevent the Progression of Non-Small Cell Lung CancerActive, not recruitingNCT03999710Phase 2
• Analysis of Biopsy Specimens to Study Responses to PD-1 or PD-L1 TherapiesWithdrawnNCT03877250
• Study of Dacomitinib and Osimertinib for Patients With Advanced EGFR Mutant Lung CancerCompletedNCT03810807Phase 1
• Randomized Study of Stereotactic Body Radiation Therapy (SBRT) in Patients With Oligoprogressive Metastatic Cancers of the Breast and LungActive, not recruitingNCT03808662Phase 2
• Continued Access to RXDX-105CompletedNCT03784378Phase 1
• Stereotactic Body Radiation Therapy for Inoperable Locally-advanced Non-small Cell Lung CancerCompletedNCT01899989Phase 1
• Changes in Brain Structure Related to Systemic Chemotherapy Treatment: A Prospective Study in Individuals Diagnosed With Non-small Cell Lung Cancer Utilizing High-resolution Structural Magnetic Resonance ImagingTerminatedNCT01473693
• Molecular Determinants of Acquired Clinical Resistance to Crizotinib in Non-small Cell Lung Cancer Harboring a Translocation or Inversion Event Involving the ALK Gene LocusCompletedNCT01300429
• Registry for Patients With Acquired Resistance to Small Molecule Kinase Inhibitors in Non-Small-Cell Lung CancerCompletedNCT00579683
• Safety and Pharmacokinetics of Jin Fu Kang in Comb w/Docetaxel for Patients w/Non-Small Cell Lung CancerCompletedNCT00260026Phase 2
• Ph I:Bevacizumab + Chemotherapy in Pts w/Malig Pleural Effusion Due to Adv NSCLCCompletedNCT00250978Phase 1
• Epothilone D in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer That Has Not Responded to Platinum-Based ChemotherapyCompletedNCT00081107Phase 2
• ABI-007 in Treating Patients With Chemotherapy-Naïve Stage IV Non-Small Cell Lung CancerCompletedNCT00077246Phase 1/2
• TLK286 in Treating Patients With Advanced Non-Small Cell Lung CancerCompletedNCT00036920Phase 2
• Combination Chemotherapy in Treating Patients With Advanced Non-Small Cell Lung CancerCompletedNCT00005806Phase 1
• Vaccine Therapy and Sargramostim in Treating Patients With Non-small Cell Lung CancerCompletedNCT00005630Phase 1
• 10-Propargyl-10-Deazaaminopterin in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung CancerCompletedNCT00004238Phase 2
• Combination Chemotherapy as Induction Therapy in Treating Patients With Stage III Non-small Cell Lung CancerCompletedNCT00003037Phase 1/2
• Radiation Therapy Using 3-Dimensional Treatment Planning in Patients With Non-small Cell Lung CancerCompletedNCT00002484Phase 1