Medtronic Cardiac Ablation Solutions clinical trials

A division of Medtronic

The registry lists 37 studies whose lead sponsor is Medtronic Cardiac Ablation Solutions. 9 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 26, 2026.

Studies

Recruiting first, then most recently updated. Showing 37 of 37. All Medtronic studies →

• Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere VT)RecruitingNCT07585968Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)RecruitingNCT07298473Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• PulseSelect™ PFA Global RegistryRecruitingNCT06393920

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Outcomes of an Optimized Workflow With PulseSelect Pulsed Field Ablation (PFA) System in Paroxysmal and Persistent Atrial FibrillationNot yet recruitingNCT07575828Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• PULSED AF Post-Approval StudyRecruitingNCT06578104

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Safety and Performance of the Affera SpherePVI™ Multi-Ablation System to Treat Paroxysmal Atrial FibrillationRecruitingNCT05115214Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Safety and Performance of the SpherePVI™ Catheter to Treat Paroxysmal Atrial FibrillationRecruitingNCT05144503Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)RecruitingNCT06703489Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Sphere-9 PAF China StudyNot yet recruitingNCT07789925Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• STOP Persistent AF PASActive, not recruitingNCT05005949

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• STOP AF First Post-Approval StudyCompletedNCT05227053

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Affera Global RegistryActive, not recruitingNCT06026345

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mapping and Ablation System (Horizon 360)Active, not recruitingNCT07308847Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• DIAMOND AF Post-Approval StudyTerminatedNCT05230524

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• SPHERE Per-AF Post-Approval StudyActive, not recruitingNCT06858306

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• DiamondTemp Global RegistryActive, not recruitingNCT04735016

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• FIRE AND ICE: Comparative Study of Two Ablation Procedures in Patients With Atrial FibrillationCompletedNCT01490814Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• DiamondTemp™ System for the Treatment of Persistent Atrial FibrillationCompletedNCT03643224Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Cryo Global RegistryCompletedNCT02752737

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• An Initial Assessment of the Sphere-9™ Catheter and Affera Mapping and Ablation SystemCompletedNCT04210622

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Assessment of the Sphere-9™ Catheter and Affera Mapping and Ablation System for Treatment of Atrial and Ventricular ArrhythmiasCompletedNCT04211441Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Treatment of Persistent Atrial Fibrillation With Sphere-9 Catheter and Affera Mapping and Ablation SystemCompletedNCT05120193Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Spanish Registry of Cryoballoon AblationCompletedNCT02785991

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Evaluation of the Phased Radio Frequency Ablation SystemTerminatedNCT01693120Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Cryoballoon Ablation for Early Persistent Atrial Fibrillation (Cryo4 Persistent AF)CompletedNCT02213731Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• DiamondTemp™ Ablation System for the Treatment of Paroxysmal Atrial FibrillationCompletedNCT03334630Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AFCompletedNCT04198701Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• ArcticLine Feasibility StudyCompletedNCT03604263Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Intracardiac CrYoablation for AtrioVentricular Nodal Reentrant TachycardiaCompletedNCT01426425Phase 3

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Catheter Cryoablation Versus Antiarrhythmic Drug as First-Line Therapy of Paroxysmal Atrial FibrillationCompletedNCT01803438Phase 4

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• STOP Persistent AFCompletedNCT03012841Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Sustained Treatment of Paroxysmal Atrial Fibrillation Post-Approval Study (STOP AF PAS)CompletedNCT01456949Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Postmarket Evaluation of the Phased Radio Frequency Ablation System (GOLD AF Registry)CompletedNCT02433613

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• STOP AF First: Cryoballoon Catheter Ablation in an Antiarrhythmic Drug Naive Paroxysmal Atrial FibrillationCompletedNCT03118518Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• Study for Atrial Fibrillation Reduction (SAFARI)CompletedNCT00267137Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• ACT DiamondTemp TempeRAture-Controlled and Contact Sensing RF Ablation Clinical Trial for Atrial FibrillationCompletedNCT02821351Not applicable

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions

• FIRE AND ICE Re-Ablations (Retrospective Data Collection)CompletedNCT03314753

  Sponsor listed in the registry: Medtronic Cardiac Ablation Solutions