Mclean Hospital: Schizophrenia trials

The registry lists 14 Schizophrenia studies with Mclean Hospital as lead sponsor. 4 are open to participants now and 8 have results posted.

Early Phase 1 1Phase 1 1Phase 2 3Phase 3 2Phase 4 1No phase 8(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial DysfunctionRecruitingNCT06191965Phase 2/3
• Cerebellar Modulation of Cognition in PsychosisRecruitingNCT06107764Not applicable
• Enhanced Coordinated Specialty Care for Early PsychosisRecruitingNCT06071858Not applicable
• Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in SchizophreniaRecruitingNCT05343598Not applicable
• Community Reinforcement and Family Training for Early Psychosis (CRAFT-EP) and Substance Use: A Pilot StudyCompletedNCT05380583Not applicableResults posted
• Families With Substance Use and Psychosis: A Pilot StudyCompletedNCT04284813Not applicableResults posted
• Effects of Intranasal Insulin on Neuroimaging Markers and Cognition in Patients With Psychotic DisordersCompletedNCT03943537Phase 2Results posted
• Targeting Cerebellum to Treat Psychosis: a Transcranial Magnetic Stimulation (TMS) StudyCompletedNCT02642029Not applicableResults posted
• Targeting a Genetic Mutation in Glycine Metabolism With D-cycloserineCompletedNCT02304432Early Phase 1Results posted
• Fixed Dose Intervention Trial of New England Enhancing Survival in SMI PatientsCompletedNCT02188121Phase 4Results posted
• Acute Glycine Pharmacodynamic StudyCompletedNCT01610011Not applicableResults posted
• Combination of Dronabinol and Clonidine for Cannabis Dependence in Patients With SchizophreniaTerminatedNCT01598896Phase 2/3Results posted
• Change in Brain Bioenergetics in Bipolar Disorder in Response to Photic StimulationWithdrawnNCT00801567Not applicable
• Augmenting Zyprexa With Naltrexone to Ameliorate Metabolic Side-EffectsCompletedNCT00567034Phase 1