Mclean Hospital: Depressive Disorder trials

The registry lists 39 Depressive Disorder studies with Mclean Hospital as lead sponsor. 0 are open to participants now and 19 have results posted.

Phase 1 6Phase 2 2Phase 3 2Phase 4 4No phase 26(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• LFMS: Initial Trial in Geriatric Bipolar DepressionTerminatedNCT02707276Not applicableResults posted
• Fixed Dose Intervention Trial of New England Enhancing Survival in SMI PatientsCompletedNCT02188121Phase 4Results posted
• Brain Mechanisms of Human MotivationCompletedNCT01976975Results posted
• Multiple Treatment Study Using Low Field Magnetic Stimulation for Bipolar DepressionCompletedNCT01929681Not applicableResults posted
• An Investigation of Early Life Stress and DepressionCompletedNCT01701258Phase 1Results posted
• Internet Based Cognitive Behavioral Therapy Effects on Depressive Cognitions and Brain FunctionCompletedNCT01598922Not applicableResults posted
• Glutamatergic and GABAergic Mediators of Antidepressant Response in Major DepressionCompletedNCT01557946Phase 4Results posted
• Exploring the Effects of Coenzyme Q10 on Bioenergetics Metabolism in Geriatric Bipolar DepressionCompletedNCT01390389Not applicableResults posted
• The Effects of Dopamine on Reward ProcessingCompletedNCT01253421Phase 1Results posted
• Lisdexamfetamine Dimesylate in Residual Symptoms and Cognitive Impairment in Major Depressive Disorder.CompletedNCT01148979Phase 4Results posted
• A Trial of SAMe for Treatment-Resistant Bipolar DepressionCompletedNCT00762268Not applicableResults posted
• Lamotrigine Therapy in Geriatric Bipolar DepressionCompletedNCT00720473Not applicableResults posted
• CoQ10 in Geriatric Bipolar DepressionCompletedNCT00720369Not applicableResults posted
• The Use of a Mitochondrial Enhancement Treatment in Bipolar DisorderCompletedNCT00719706Phase 2Results posted
• Low Field Magnetic Stimulation in Mood Disorders Using the LFMS DeviceCompletedNCT00578383Not applicableResults posted
• Riluzole in the Treatment of Bipolar DepressionCompletedNCT00544544Not applicableResults posted
• AndroGel in Men With Major Depression and Incomplete Response to Antidepressant TreatmentCompletedNCT00304746Phase 4Results posted
• Magnetic Resonance Imaging Study of Geriatric DepressionCompletedNCT00245557Not applicableResults posted
• The Effects of Wellbutrin (Bupropion) on Residual and Cognitive Symptoms in SSRI-treated DepressionCompletedNCT00125957Phase 3Results posted
• Effectiveness of HabitWorks and Symptom Tracking for Anxiety and DepressionCompletedNCT07025486Not applicable
• Feasibility of Collateral Information Review and Its Impact on Clinical Decision-MakingCompletedNCT04635748
• Behavioral and Electrophysiological Effects of Ketamine in Treatment-Resistant DepressionCompletedNCT04239963
• Effects of Attention Training Interventions on DepressionTerminatedNCT04184206Not applicable
• Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious DepressionTerminatedNCT03999736Phase 1/2
• Electrophysiological Correlates of Cognition in DepressionTerminatedNCT03998748Not applicable
• Study of Dronabinol Treatment for Depression and/or Anxiety in Older PatientsWithdrawnNCT03369639
• McLean and Genomind Prospective StudyCompletedNCT03113890Not applicable
• Sex, Hormones and Gamma-Aminobutyric Acid (GABA) in Stress Induced Anhedonia in DepressionCompletedNCT03031665
• Neuroimaging Studies of Reward Processing in DepressionCompletedNCT03026036
• Effect of Nicotine on Brain Reward PathwaysCompletedNCT02346539Phase 1
• Functional Brain Imaging Study of Response to Repetitive TMS (rTMS) Treatment of Major DepressionStatus unknownNCT01768052
• Neural Components Underlying the Treatment of Adolescent DepressionCompletedNCT01717508Not applicable
• Depression and Dopamine Transporter Function Study Using C-11 AltropaneCompletedNCT01701141
• Dopamine Neurotransmission in Major DepressionCompletedNCT01659814
• Functional and Neurochemical Correlates of Treatment Response in Major Depressive DisorderTerminatedNCT01598324
• Low Field Magnetic Stimulation (LFMS) in Mood Disorders: 6 TreatmentsSuspendedNCT01557192Phase 1
• Treatment Resistant Geriatric Depression in Primary CareCompletedNCT01392287Phase 1
• Low Field Magnetic Stimulation Treatment for Bipolar DepressionTerminatedNCT00217217Phase 3
• Understanding Brain Reward Responses in Individuals With Major Depressive DisorderCompletedNCT00183755