Massachusetts General Hospital: Obesity trials

The registry lists 44 Obesity studies with Massachusetts General Hospital as lead sponsor. 12 are open to participants now and 14 have results posted.

Early Phase 1 2Phase 1 2Phase 2 6Phase 4 2No phase 32(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Switching to Oral Weight Management Pharmacotherapy to Prevent Weight Regain After GLP-1 Therapy DiscontinuationNot yet recruitingNCT07729332Phase 4
• The Effects of Lumateperone on Obesity and Physiologic Aging and Their Association With Antidepressant Response in Bipolar DepressionRecruitingNCT07699445Phase 4
• Setmelanotide to Treat Obesity in a Patient With Pseudohypoparathyroidism Type 1a (PHP1a)Enrolling by invitationNCT07496463Phase 2
• Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist TreatmentRecruitingNCT07226947Not applicable
• BILe Acid-gut Microbiome Axis MODification Through Diet Education for Colorectal Cancer PreventionRecruitingNCT07162337Not applicable
• Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal TumorsRecruitingNCT07095517Phase 1
• Building ConnectionsRecruitingNCT07091032Not applicable
• Risk Informed Obesity Care Plan PilotEnrolling by invitationNCT07028814
• Inhaled Nitric Oxide in Severe ObesityNot yet recruitingNCT06675435Not applicable
• Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic ConditionsRecruitingNCT06557005Not applicable
• Effect of Tirzepatide and Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With ObesityRecruitingNCT05933499Phase 2
• Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income PopulationRecruitingNCT05799222
• First Heroes: Engaging Fathers in the First 1000 DaysCompletedNCT04477577Not applicableResults posted
• Relative Sarcopenia and Cardiometabolic Risk in Young Adults With ObesityCompletedNCT04195061Results posted
• PREMIER: PREvention of Metabolic Illness Through prEcision nutRitionCompletedNCT04148482Not applicableResults posted
• Implementation and Evaluation of a Before School Physical Activity Program in Revere, MACompletedNCT03805295Not applicableResults posted
• Growth Hormone Releasing Hormone Analog to Improve Nonalcoholic Fatty Liver Disease and Associated Cardiovascular RiskCompletedNCT03375788Phase 2Results posted
• Connect 4 Health: An Intervention to Improve Childhood Obesity OutcomesCompletedNCT02124460Not applicableResults posted
• Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in HumansCompletedNCT01762046Phase 1Results posted
• Study of Growth Hormone and Bone in ObesityCompletedNCT01724489Not applicableResults posted
• Characterization of Transient Alterations of Cutaneous Sensory Nerve Function by CryolipolysisCompletedNCT01673113Not applicableResults posted
• Effects of Acipimox on Mitochondrial Function in ObesityCompletedNCT01488409Phase 2Results posted
• Growth Hormone Treatment on Phosphocreatine Recovery in ObesityCompletedNCT01421589Not applicableResults posted
• Effect of Recombinant Human Growth Hormone (rhGH) on Abdominal Fat and Cardiovascular Risk in Obese GirlsCompletedNCT01169103Phase 2Results posted
• Effectiveness of Growth Hormone Releasing Hormone in Reducing Abdominal Fat in People Who Are ObeseCompletedNCT00675506Phase 2Results posted
• Growth Hormone, Cardiovascular Risk, and Visceral AdiposityCompletedNCT00131378Not applicableResults posted
• WeighT LOSS Surgery and Comprehensive Cardiometabolic Responses to to EXerciseCompletedNCT06576050
• Pediatric Healthy Weight ClinicCompletedNCT05020314Not applicable
• Connect for Health Pediatric Weight Management ProgramCompletedNCT04042493Not applicable
• The First 1,000 Days Program: Maternal-Child Obesity Prevention in Early LifeCompletedNCT03191591Not applicable
• Nasal Continuous Positive Airway Pressure and Airway Patency in Obese PatientCompletedNCT03024723
• Clinical & Community Approaches to Weight ManagementCompletedNCT03012126Not applicable
• An Integrated Closed-loop Feedback System for Pediatric Cardiometabolic DiseaseStatus unknownNCT02659163Early Phase 1
• Effects of Weight Loss Surgery on Bone Health in AdolescentsActive, not recruitingNCT02557438
• Effects of PEEP on Heart and Lungs in Obese SubjectsStatus unknownNCT02523352Not applicable
• Effects of Different PEEP Levels on Work of Breathing in Morbidly Obese Patients Prior to and After ExtubationWithdrawnNCT02492113Not applicable
• Oxytocin Effects on Food Motivation PathwaysCompletedNCT02276677Early Phase 1
• Mass in Motion Kids in the Clinical SettingCompletedNCT02110615Not applicable
• Randomized Trial of Financial Incentives to Reduce Sugar-sweetened Beverage Purchases by Low-income, Latino FamiliesCompletedNCT01990508Not applicable
• Effect of Body Positioning on Upper Airway Patency During Induction of Anesthesia in Obese PatientsCompletedNCT01811069
• Abdominal Obesity, Cardiovascular Inflammation, and Effects of Growth Hormone Releasing Hormone AnalogueWithdrawnNCT01632592Not applicable
• Intensive Exercise to Improve Mitochondrial Dysfunction in Pediatric ObesityStatus unknownNCT00962806Not applicable
• Mitochondrial Function in Pediatric ObesityStatus unknownNCT00577174
• Prevalence and Cardiovascular Effects of Growth Hormone Deficiency in Abdominal ObesityCompletedNCT00562796