Massachusetts General Hospital: Alzheimer Disease trials

The registry lists 27 Alzheimer Disease studies with Massachusetts General Hospital as lead sponsor. 8 are open to participants now and 9 have results posted.

Early Phase 1 1Phase 1 4Phase 2 6Phase 4 1No phase 18(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Biomarker-based Trial of NPC-1 for Alzheimer's PathologyRecruitingNCT07236190Phase 2
• Transcranial Magnetic Stimulation Treatment for Alzheimer's DiseaseRecruitingNCT06538311Early Phase 1
• The Care for America's Aging StudyNot yet recruitingNCT06021704Not applicable
• Individual Closed-Loop Neuromodulation Therapy for Alzheimer's DiseaseRecruitingNCT05904132Not applicable
• Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical ADRecruitingNCT05881239
• Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's DiseaseRecruitingNCT05776641Not applicable
• Assess Fibrin in Brains With AD/ADRDRecruitingNCT05336695Phase 1/2
• Care Planning for a Loved One With Dementia: Knowledge, Preparing for Decisions, and EmotionsRecruitingNCT05165186Not applicable
• Supporting Our Caregivers In ADRD Learning (SOCIAL)CompletedNCT06276023Not applicableResults posted
• MASC: Reducing Stress for CaregiversCompletedNCT05847153Not applicableResults posted
• Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket TrialCompletedNCT05189106Phase 1/2Results posted
• A Pilot Study of the Effects of BCG Immunization on CSF and Blood-based Biomarkers in Older Adults.CompletedNCT04507126Phase 2Results posted
• Acupuncture to Reduce Anxiety in Alzheimer's Disease (AD) and AD Related DementiasTerminatedNCT03814382Not applicableResults posted
• A Pilot of Methylphenidate in Mild Cognitive Impairment and Dementia Participants.CompletedNCT03811847Phase 4Results posted
• Effect of Modulating Gamma Oscillations Using tACSCompletedNCT03412604Not applicableResults posted
• tACS for Amyloid-β Reduction in Alzheimer's DiseaseCompletedNCT03290326Not applicableResults posted
• Zolpidem CR and Hospitalized Patients With DementiaCompletedNCT00814502Not applicableResults posted
• Pilot Study of a Brain Health Program in Senior CentersCompletedNCT07424443Not applicable
• Toolkit for Experiential Well-beiNg in Dementia (TEND)WithdrawnNCT06257563Not applicable
• TMS as a Treatment for Apathy in Alzheimer's DiseaseTerminatedNCT05389644Not applicable
• Olfactory Deficits in Neurologic DiseaseCompletedNCT05019014
• Exploring the Utility of [18F]3F4AP for Demyelination Imaging in Controls, Neurodegeneration and Traumatic Brian InjuryActive, not recruitingNCT04710550Phase 1
• TMS in Preclinical and Prodromal AD: Modulation of Brain Networks and MemoryTerminatedNCT04294888Not applicable
• A Pilot Open Labeled Study of Tacrolimus in Alzheimer's Disease.WithdrawnNCT04263519Phase 2
• Gamma Induction for Alzheimer's DiseaseCompletedNCT03880240Phase 1/2
• Chromatic Pupillometry to Assess the Melanopsin-Light Pathway in Progressive Supranuclear PalsyStatus unknownNCT03330353
• Differential Effects of Various Anesthetic Agents on Cognitive Function in Patients With Alzheimer's DiseaseWithdrawnNCT01870453