M.D. Anderson Cancer Center: all 3,044 studies

Page 15 of 31. Open to participants first (578), then studies with results posted, then the rest; newest registration first within each.

• STRIVE: A Single-arm Phase 2 Study on Treatment of Lung Squamous Cell Carcinoma by Tiragolumab Plus Ivonescimab for Patients Who Progressed on Platinum Doublets and Anti-PD-1/PD-L1WithdrawnNCT07038915Phase 2
• 177Lu-PSMA-617 in Metastatic Castration Resistant Prostate Cancer (mCRPC) With Bone Marrow Involvement and CytopeniaWithdrawnNCT07025512Phase 2
• Study of Lenvatinib Plus Pembrolizumab in IO Refractory mRCC Patients With Brain MetastasesWithdrawnNCT07011849Phase 2
• Phase 2, Single-arm Trial of BMS-986340 in Association With Nivolumab, Trifluridine/Tipiracil and Bevacizumab for Patients Refractory to Standard of Care Treatment and With Microsatellite-stable Colorectal CancerSuspendedNCT07011550Phase 2
• A Phase Ib Study of Novel Combination (New) of Low Dose Oral CyclophoSphamide (s) to Potentiate Axatilimab (A) + Retifanlimab (R) in Treating Metastatic Triple Negative Breast Cancer (TNBC)SuspendedNCT06959537Phase 1
• Supporting Informed Decision Making About Multi-cancer Early Detection TestingSuspendedNCT06870916
• The Effect of the Prostate Cancer Foundation Screening Guidelines for Black Men on Intention to Screen in Faith-based CommunitiesCompletedNCT06838325Not applicable
• Phase II Study of Atezolizumab and Tiragolumab With ctDNA for HPV-positive SCCWithdrawnNCT06762808Phase 2
• Phase I/Ib Trial of TIraGolumab, AtEzolizumab, and RadScopal Radiation in Patients With Advanced Solid Malignancies (TIGER)Active, not recruitingNCT06760481Phase 1
• A Phase 2 Clinical Trial Evaluating the Efficacy and Safety of Dual Immune Checkpoint Inhibition With Anti-PD-L1 (Atezolizumab) and Anti-TIGIT (Tiragolumab) in Cancer of Unknown PrimaryActive, not recruitingNCT06754501Phase 2
• Impact of Diaphragmatic Breathing Coaching on Deep Inspiration Breath Hold Reproducibility and Organ ProtectionActive, not recruitingNCT06747533Not applicable
• Patient-identified Values as Outcome Targets (PIVOT) Feasibility Pilot TrialCompletedNCT06736600Not applicable
• A Randomized Phase 2 Trial of Nivolumab, Relatlimab Plus Ipilimumab vs. Nivolumab Plus Ipilimumab in First-line Advanced Renal Cell Carcinoma (RCC)Active, not recruitingNCT06708949Phase 2
• A Phase 2 Trial of Glofitamab for Minimal Residual Disease in Patients With Large B-cell LymphomaWithdrawnNCT06670105Phase 2
• ALLG AMLM26 INTERCEPT (Investigating Novel Therapy to Target Early Relapse and Clonal Evolution as Pre-emptive Therapy in AML): A Multi-arm, Precision-based, Recursive, Platform TrialActive, not recruitingNCT06664879Phase 1/2
• Symptom Burden and Health Related Quality of Life of Cancer Patients With Concurrent Heart FailureActive, not recruitingNCT06656715
• A Phase 2 Study of INCB57643 (BET Inhibitor) in Combination With Ruxolitinib in JAK Inhibitor-naïve Patients With MyelofibrosisWithdrawnNCT06619522Phase 2
• Closed Loop Spinal Cord Stimulation for Chemotherapy Induced Peripheral Neuropathy, a Pilot Study.SuspendedNCT06616649Not applicable
• A Phase 2 Study Evaluating Olutasidenib in Combination With Hypomethylating Agents in Patients With IDH1-mutated Higher-risk Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Advanced Myeloproliferative NeoplasmWithdrawnNCT06597734Phase 2
• Feasibility of the Use of Weighted Blankets to Improve Sleep Among Patients With Hematological MalignanciesActive, not recruitingNCT06584955Not applicable
• Evaluating Mechanical Properties of Post-Mastectomy Skin Flaps to Estimate Reconstruction Risks, the EMPOWER StudyActive, not recruitingNCT06584396
• 18F-FSPG PET/CT as a Non-Invasive Imaging Biomarker for Treatment Response to Chemoradiation in Esophageal CancerTerminatedNCT06549413
• ACT-Together (Acting on Cancer Testing-Together)Active, not recruitingNCT06549153Not applicable
• Establishing Daily Applicable Parameters for Using Magnetic Resonance Spectroscopy of Spinal CordCompletedNCT06548776Not applicable
• Opiophobia in Postsurgical Adults With CancerActive, not recruitingNCT06536283
• Impact of Perioperative Anesthetic Management on Renal Cancer Progression.WithdrawnNCT06536244
• AIM4 AI and Mechanistic Modeling in Molecular MedicineWithdrawnNCT06535828
• GATE1: A Multicenter Phase II Study of Pirtobrutinib, Rituximab and Venetoclax Combination Therapy for Patients With Previously Untreated Mantle Cell LymphomaActive, not recruitingNCT06522386Phase 2
• Phase I Trial of MT-0169 in CD38+ Acute Leukemia With Relapsed/Refractory or Measurable Residual DiseaseWithdrawnNCT06522373Phase 1
• Brigatinib Plus Chemotherapy or Local Consolidation Therapy in ALK Positive Advanced Non-small Cell Lung Cancer (BrightStar-2)WithdrawnNCT06522360Phase 2
• A Phase I Study Investigating the Combination of Cladribine, Low Dose Cytarabine and Sorafenib Alternating With Decitabine in Pediatric Relapsed and Refractory Acute LeukemiasWithdrawnNCT06474663Phase 1
• Phase I Study of Q702 With Azacitidine and Venetoclax for Relapsed or Refractory Acute Myeloid LeukemiaActive, not recruitingNCT06445907Phase 1
• Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient MalignanciesActive, not recruitingNCT06444880Phase 2
• A Virtual, Group-Based, Expressive Writing Intervention for Survivors of Adolescent and Young Adult CancerActive, not recruitingNCT06434402Not applicable
• Phase II Study of REPotrectinib With or Without Fulvestrant in Patients With Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Who Received a Prior Endocrine Therapy in Combination With Cyclin-dependent Kinase 4 and 6 Inhibitor (REPLOT Trial)TerminatedNCT06408168Phase 2
• Health Benefits of Writing Therapy Among Asian American Cancer SurvivorsActive, not recruitingNCT06367959Not applicable
• Study of VG2025 Delivered Intraperitoneally in Patients With Advanced Solid Tumors With CarcinomatosisWithdrawnNCT06365918Phase 1
• Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)Active, not recruitingNCT06358430Phase 1
• A Phase II Study of Rivoceranib for Patients With Recurrent or Metastatic Olfactory NeuroblastomaWithdrawnNCT06308575Phase 2
• A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or DeletionsActive, not recruitingNCT06308419Phase 1
• A Phase I/II Trial to Assess the Efficacy and Toxicity of ASTX727 (Oral Decitabine/Cedazuridine) for the Treatment of Hematological Neoplasms After Allogeneic Stem Cell TransplantationWithdrawnNCT06297629Phase 2
• A Phase II Study Bolstering Outcomes by Optimizing Immunotherapy Strategies With Evolocumab and Nivolumab in Patients With Metastatic Renal Cell Carcinoma (BOOST-RCC)Active, not recruitingNCT06284564Phase 2
• Phase I/II Study of a Combination of Decitabine and Cedazuridine (ASTX727) and ASTX029, an ERK Inhibitor, for Patients With RAS Pathway Mutant Myelodysplastic Syndromes and Myelodysplastic/Myeloproliferative NeoplasmsWithdrawnNCT06284460Phase 1/2
• Understanding Patient Experience Among Asians at MD AndersonActive, not recruitingNCT06259253
• Impact of a Prebiotic Food-enriched Diet (PreFED) in Combination With Ipilimumab/Nivolumab Combination Immune Checkpoint Blockade (ICB) in ICB-refractory Melanoma PatientsActive, not recruitingNCT06250335Phase 2
• A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid TumorsActive, not recruitingNCT06237881Phase 1/2
• 5x-Multiplier vs 3-Tier Model for Discharge Opioid Prescriptions After Intra-abdominal Cancer Surgery: A Randomized Clinical TrialCompletedNCT06232577Phase 2
• Effect of Olanzapine on Opioid Craving and Misuse Among Patients Receiving Opioids for Cancer-related Pain: A Pilot Double-Blind, Randomized Control TrialActive, not recruitingNCT06200181Phase 3
• A Trial of YL-13027 in Combination With Gemcitabine and Nab-paclitaxel in Patients With Refractory Metastatic Pancreatic CancerTerminatedNCT06199466Phase 1
• Phase II Randomized-registry Embedded Study of Lymphoscintigraphy for Oropharyngeal Neoplasms to Enable Risk-adapted Nodal Guidance for Robotic Surgery and/or Radiotherapy (LONE-RANGR2)Active, not recruitingNCT06167291Phase 2
• Evaluation of Hereditary Cancer Educational VideosActive, not recruitingNCT06157801
• Phase Ib Trial of the KRAS G12C Inhibitor Adagrasib (MRTX849) in Combination With the PARP Inhibitor Olaparib in Patients With KRAS G12C Mutated Advanced Solid Tumors, With a Focus on Gynecological, Breast, Pancreatic and KEAP1 Mutated Non-small Cell Lung CancersTerminatedNCT06130254Phase 1
• A Digital Art Activity to Enhance Self-Disclosure and the Detection of Psycho-social Distress in Adult Cancer PatientsActive, not recruitingNCT06127121
• A Pilot, Open-Label Study of Luspatercept for Patients With Lower Risk Myelodysplastic Syndromes (MDS)Active, not recruitingNCT06113302Phase 2
• A Phase 1B/2A Trial of Combination of ASTX727 With ASTX029 in Acute Myeloid LeukemiaWithdrawnNCT06113289Phase 1/2
• Phase 2 Study to Evaluate the Efficacy of Regorafenib in Specific GIST Mutation Subsets (KIT Exon 17, 18, or 14 Mutation and SDHB Deficient GIST) in the Post-imatinib Second-line Setting.Active, not recruitingNCT06087263Phase 2
• Phase I/II Study of SY-1425 (Tamibarotene) in Combination With Azacitidine and Venetoclax for Patients With Chronic Myelomonocytic LeukemiaWithdrawnNCT06085638Phase 1/2
• PhI/II Study of Amivantamab and Tepotinib Combo in MET-altered Non-small Cell Lung CancerActive, not recruitingNCT06083857Phase 1/2
• Immunogenicity and Clinical Efficacy of 20-valent Pneumococcal Conjugate Vaccine (PCV20) in Lymphoma Survivors After Treatment With Anti-CD20 TherapyActive, not recruitingNCT06049134Phase 4
• A Phase 1, Open-Label, Sequential Cross-over, Bioavailability/Bioequivalence Study to Compare the Pharmacokinetics of Oral Cladribine With the Reference Listed Drug, Intravenous CladribineTerminatedNCT06021600Phase 1
• A Pilot Study to Assess the Clinical Utility of 18F-Fluciclovine (Axumin) PET-CT for Detecting True-versus Pseudo-Progression of Brain Metastases on ImmunotherapyTerminatedNCT06015295Not applicable
• A Study Evaluating Atezolizumab and Bevacizumab Plus ADI-PEG 20 in Patients With Locally Advanced / Metastatic Hepatocellular CarcinomaWithdrawnNCT06006286Phase 1/2
• The Phoenix Trial: Phase II Trial of Cemiplimab for the Non-operative Management of Localized dMMR Colon CancerActive, not recruitingNCT05961709Phase 2
• A Phase I Study of Mosunetuzumab for Relapsed or Refractory B-Cell Acute Lymphoblastic LeukemiaWithdrawnNCT05961696Phase 1
• Reminder Messages for Lung Cancer ScreeningActive, not recruitingNCT05952778
• A Pilot Clinical Trial to Determine the Feasibility of Administering an Electronic Tool to Assess Postoperative pAin, Nausea, and Vomiting in English or Spanish-Speaking Pediatric Patients With Neoplastic Conditions.CompletedNCT05933252Not applicable
• An Open-Label, Single Center Phase 2 Study of Magrolimab, Rituximab and Radiation as Bridging Strategy Before CAR T-Cell Therapy in Patients With Relapsed or Refractory Large B-cell LymphomaWithdrawnNCT05929716Phase 2
• Geriatric Care Survivorship Intervention for Improving the Overall Health of Older Adults With Stage I-III Breast Cancer Who Have Completed Curative TreatmentActive, not recruitingNCT05928325Not applicable
• Harmony & Health: A Culturally Adapted Mindbody Intervention to Reduce Sitting Time and Improve Psychosocial Wellbeing in Black AdultsActive, not recruitingNCT05922943Not applicable
• Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic CancerActive, not recruitingNCT05922930Phase 1/2
• PET Adapted Brentuximab Vedotin and Pembrolizumab in Combination With Doxorubicin and Dacarbazine in Classic Hodgkin LymphomaActive, not recruitingNCT05922904Phase 2
• An Evaluation of the Implementation of the Care and Monitoring at Home Program- A New Paradigm for Acute Care Management of Cancer PatientsSuspendedNCT05904899
• Regorafenib and XmAb20717 in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy (RX-CROME)WithdrawnNCT05900648Phase 2
• Accelerated Recovery After MIS Hepatectomy (ARAMIS Hep) to Support Early Discharge for Patients Undergoing Minimally Invasive Liver ResectionActive, not recruitingNCT05879159Not applicable
• HEALTH4CLL2: A Randomized Waitlist Control Trial of Behavioral Interventions in Patients With Chronic Lymphocytic LeukemiaActive, not recruitingNCT05879133Not applicable
• Randomized Study of Neo-adjuvant and Adjuvant Pembrolizumab With and Without Targeted Blood Brain Barrier Opening Using Exablate MRI-guided Focused Ultrasound (Exablate MRgFUS) for Recurrent GlioblastomaWithdrawnNCT05879120Phase 2
• Study Using Hyperpolarized 13C-Pyruvate Magnetic Resonance Spectroscopic Imaging in Patients With Pancreatic Cysts Undergoing Surgical ResectionSuspendedNCT05873699Phase 1
• Early Assessment of Ovarian Cancer Aggressiveness by Metabolic ImagingSuspendedNCT05866679Phase 1
• A Phase I Study of Adagrasib and Durvalumab for Treatment of Advanced Non-small Cell Lung Cancers and Gastro-intestinal Cancers Harboring KRAS G12C MutationsWithdrawnNCT05848843Phase 1
• Randomized Pre-surgical Window-of-Opportunity Trial of TTI-101 in Patients With Stage II-IV Resectable HPV-negative Squamous Cell Carcinoma of the Head and NeckWithdrawnNCT05845307Early Phase 1
• Assessment of Patient Experience and Needs for Patients Undergoing Invasive Inguinal Lymph Node Procedures for Penile CancerSuspendedNCT05842031
• Sexual Dysfunction in Palliative Care Patients: An Assessment of Patient's PerspectiveCompletedNCT05837117
• Tele-PancFit: A Multi-site Trial of Video-based Strengthening Exercise Prehabilitation for Patients With Resectable Pancreatic CancerActive, not recruitingNCT05836870Phase 3
• The Use of Cannabis (Marijuana) and Cannabidiol (CBD) Among Cancer Patients: A Pilot StudyActive, not recruitingNCT05836857
• Phase I Study of TH1 Dendritic Cell Immunotherapy for the Treatment of Cutaneous AngiosarcomaWithdrawnNCT05799612Phase 1
• Multi-site Feasibility and Acceptability of a Faith-based Mind-body Intervention for Black AdultsActive, not recruitingNCT05791981Not applicable
• Developing a Culturally Relevant Supportive Care Program for Black Patients Dealing With Advanced CancerActive, not recruitingNCT05763797Not applicable
• Smartphone-delivered Scheduled Smoking With Compliance Facilitation as an Adjunct Cessation Therapy: a Feasibility StudyActive, not recruitingNCT05763771Not applicable
• Harmony & Health: Feasibility of a Movement Intervention to Improve Psychosocial Wellbeing in Black Adults in Northeast TexasActive, not recruitingNCT05761964Not applicable
• Phase 2 Study Evaluating the Efficacy of the Combination of DKN-01 (DKK1 Inhibitor, Leap Therapeutics) and Pembrolizumab in the Treatment of Advanced or Recurrent Endometrial CancerActive, not recruitingNCT05761951Phase 2
• 3D Printed Breast Models in the Surgical Management of Breast CancerActive, not recruitingNCT05755984Not applicable
• Vapocoolant Analgesia for Breast LymphoscintigraphyTerminatedNCT05744557Not applicable
• TriNav Infusion System for the Evaluation of Fidelity Between 99mTc-MAA and Y90-Microspheres Hepatic Distribution for Dosimetry Treatment PlanningActive, not recruitingNCT05743842Not applicable
• Phase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal CancerActive, not recruitingNCT05722327Phase 1
• A Randomized Trial Comparing a Ventilatory Strategy To Prevent Atelectasis Versus a Lateral Decubitus Strategy During Robotic Bronchoscopy (VESPA vs. LADS Trial)CompletedNCT05714033Not applicable
• A Phase Ib Study to Evaluate the Safety and Preliminary Efficacy of IL6-receptor Antibody Sarilumab in Combination With antiPD1 Antibody Cemiplimab for Patients With Non-small Cell Lung Cancer.Active, not recruitingNCT05704634Phase 1
• Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and OsteosarcomaSuspendedNCT05703854Phase 1/2
• A Phase 1/2, Open-label Study of Valemetostat in Combination With Rituximab and Lenalidomide in Relapsed or Refractory Follicular LymphomaActive, not recruitingNCT05683171Phase 1/2
• Phase 2 Trial of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab in Patients With Newly Diagnosed PD-L1 CPS Positive Resectable Stage 3-4 Oral Cavity Squamous Cell Carcinoma (OCSCC).Active, not recruitingNCT05681039Phase 2
• Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) InterventionActive, not recruitingNCT05677048Not applicable

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