M.D. Anderson Cancer Center: Head and Neck Neoplasms trials

The registry lists 63 Head and Neck Neoplasms studies with M.D. Anderson Cancer Center as lead sponsor. 8 are open to participants now and 13 have results posted.

Early Phase 1 2Phase 1 13Phase 2 20Phase 3 1No phase 31(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Ph2, Colchicine For Inflammatory Carotid Injury And Disease Evolution After RadiotherapyNot yet recruitingNCT07856719Phase 2
• Understanding the Role of MyCareGorithm as a Visual Digital Platforms in Cancer Treatment Education and Patient Comprehension of Oncology Treatment PlansNot yet recruitingNCT07852949Not applicable
• Phase I Study of Preconditioning Radiation Therapy With IL-15 Transduced TGFBR2 KO CAR.TROP2-engineered Cord Blood-derived NK Cells in Patients With Advanced Head and Neck Cancer (RADIANCE-NK)RecruitingNCT07101432Phase 1
• Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose)RecruitingNCT06912763Phase 2
• Pilot Study of Management of Facial Paralysis in the Oncologic Patient: Nerve Transfer Techniques to Improve Facial Function and Quality of LifeRecruitingNCT06667427Not applicable
• Web-Based Program in Helping Patients With Head and Neck Cancer Adhere to Swallowing Exercises and Coping StrategiesRecruitingNCT04003051Phase 2
• Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Diagnosing Osteoradionecrosis in Patients With Head and Neck Cancer That Is Primary, Has Come Back, or Has Spread to Other Places in the BodyRecruitingNCT03145077Not applicable
• Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"RecruitingNCT01365169Not applicable
• Flexible Intubation Scope With or Without Video Laryngoscope in Supporting Endotracheal Tube Placement in Patients With Head and Neck Cancer Before SurgeryCompletedNCT03757091Not applicableResults posted
• Minocycline for Postsurgical Symptom Reduction in Head and Neck CancerTerminatedNCT02055963Phase 2Results posted
• Study of Chemotherapy With Cisplatin/Carboplatin, and Docetaxel With or Without Erlotinib in Patients With Head and Neck Squamous Cell Carcinomas Amenable for Surgical ResectionCompletedNCT01927744Phase 2Results posted
• Single Agent Armodafinil for Patient-Reported Fatigue Following Radiation Therapy for Head and Neck CancerCompletedNCT01330446Phase 1/2Results posted
• Symptom Burden in Head and Neck CancerTerminatedNCT01219673Phase 1/2Results posted
• Trial of RAD001 and Erlotinib With Recurrent Head and Neck Squamous Cell CarcinomaCompletedNCT00942734Phase 2Results posted
• Celecoxib as Adjuvant Biologic Therapy in Patients With Head and Neck and Lung CancerTerminatedNCT00527982Phase 2Results posted
• A Pilot Trial of Image-Guided Adaptive Radiotherapy for Head and Neck CancerCompletedNCT00490282Not applicableResults posted
• Imatinib Mesylate (Gleevec) and Docetaxel in Patients With Head and Neck Squamous Cell CancerCompletedNCT00485485Phase 2Results posted
• Amifostine With IMRT for Submandibular and Sublingual Salivary Sparing During Head and Neck Cancer TreatmentTerminatedNCT00409331Phase 2Results posted
• Cetuximab, Carboplatin, and Paclitaxel Followed by Radiation Therapy, With or Without Cisplatin, in Treating Patients With Metastatic Head and Neck CancerCompletedNCT00301028Phase 2Results posted
• Study of ABT-510 (Thrombospondin Analogue) in Patients With Advanced Head and Neck CancerCompletedNCT00113334Phase 1/2Results posted
• OSI-774/Cisplatin/Taxotere in Head & Neck Squamous Cell CancerCompletedNCT00076310Phase 2Results posted
• A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid TumorsActive, not recruitingNCT06237881Phase 1/2
• Non-randomized, Open-label Study of Intralesional Nivolumab for High Risk Oral Premalignant LesionsActive, not recruitingNCT05327270Phase 1
• 3D Printed Oral Stents for Patients With Head and Neck Cancer Receiving Radiation TherapyTerminatedNCT05126797Not applicable
• ProvoxLife Adoption Trends for Heat-Moisture ExchangerActive, not recruitingNCT05036330
• Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck CancerCompletedNCT04870840Phase 1
• Yoga Program for Improving the Quality of Life in Couples Coping With CancerActive, not recruitingNCT04607590Not applicable
• Magnetic Resonance (MR) Imaging & Blood Biomarkers for Head and Neck CancerActive, not recruitingNCT03491176
• Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal CancerActive, not recruitingNCT03224000Phase 2
• Dyadic Yoga Intervention for Patient With Head and Neck Cancer Undergoing Radiotherapy and Their Family CaregiversActive, not recruitingNCT03114501Not applicable
• Cough, Expiratory Training, and Chronic Aspiration After Head and Neck RadiotherapyActive, not recruitingNCT02662907Not applicable
• Neurological Effects of Acupuncture to Prevent Radiation-induced XerostomiaCompletedNCT02292368Not applicable
• Exploring the Neuro-Immune Basis of Cancer-Related Fatigue Using Behavioral MeasuresCompletedNCT02255773Not applicable
• Sensor-Assisted Prevention of Dehydration in Head and Neck Cancer PatientsActive, not recruitingNCT02253238Not applicable
• Ferumoxytol - Iron Oxide Nanoparticle Magnetic Resonance Dynamic Contrast Enhanced MRITerminatedNCT01895829Early Phase 1
• Neuropathic Pain in Head and Neck CancerStatus unknownNCT01846286
• Testing Accountability in Patient AdherenceStatus unknownNCT01844557
• Mirror Grant - Toward an Understanding of Body Image Adaptation Following Surgical Treatment for Head and Neck CancerCompletedNCT01432132
• TEST: Registry for Endoscopic Head and Neck SurgeryTerminatedNCT01412749
• Controlled Trial Of Acupuncture To Prevent Radiation-Induced XerostomiaActive, not recruitingNCT01266044Phase 3
• Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell CarcinomaActive, not recruitingNCT01154920Phase 2
• Smoking Cessation Treatment for Head & Neck Cancer PatientsActive, not recruitingNCT01098955Early Phase 1
• Chlorhexidine Gel Therapy for Cariogenic Oral MicrofloraCompletedNCT01036412Phase 1
• Detection of Cervical Lymph Node Metastases With a High-Resolution Positron Emission Tomography (PET) Imaging SystemCompletedNCT01030497
• Reflux Disease in Head and Neck Cancer Patients Undergoing Radiation TherapyWithdrawnNCT00928161Not applicable
• Xerostomia Pilot Fudan: Acupuncture for Prevention of Radiation-Induced XerostomiaStatus unknownNCT00862550Not applicable
• Topical Cyclosporine vs. Placebo for Epiphora Associated With DocetaxelWithdrawnNCT00824811Phase 2
• Spousal Support in Head and Neck CancerCompletedNCT00824252
• Body Image Functioning Among Surgically Treated Patients With Head and Neck CancerCompletedNCT00824174
• Adherence to Swallowing Exercises in Head and Neck CancerStatus unknownNCT00761397
• Sexual Behavior in Head and Neck Cancer PatientsStatus unknownNCT00662662
• Sexual Behavior in Oropharyngeal Patients Versus Head and Neck Cancer Patients, With or Without HPV InfectionCompletedNCT00508170
• Pemetrexed (Alimta) in Patients With Head and Neck Squamous Cell CancerCompletedNCT00507858Phase 1
• Depression and Adherence in Head and Neck CancerActive, not recruitingNCT00498875
• An Exploratory Study on Optical Assessment of Oral MucositisTerminatedNCT00488332
• Vanguard Study for Head and Neck Cancer or Non-Small Cell Lung Cancer (NSCLC) PatientsCompletedNCT00352391
• PEG-interferon Alfa-2b in Treating Patients With Stage II, Stage III, or Stage IV Head and Neck Cancer That Can Be Removed By SurgeryCompletedNCT00276523Phase 2
• Erlotinib and Docetaxel With Concomitant Boost Radiation Therapy (XRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)CompletedNCT00113347Phase 1
• 4-HPR and FTI in Head and Neck Squamous Cell Carcinoma (HNSCC)TerminatedNCT00102635Phase 1
• A Phase IB Study Of Oral SCH 66336 Preoperatively In Patients With Head And Neck Squamous Cell CancerCompletedNCT00038584Phase 1
• Assessment of Head and Neck Tumor Hypoxia Using 18F-FluoromisonidazoleWithdrawnNCT00038038Not applicable
• Fenretinide in Treating Patients With Recurrent or Metastatic Head and Neck CancerCompletedNCT00006471Phase 2
• Radiation Therapy Plus Fludarabine in Treating Patients With Locally Advanced Cancer of the Mouth, Pharynx, or LarynxCompletedNCT00004246Phase 1